{"title":"Organoboron Compounds","description":"\u003cdiv style=\"max-width:700px;font-family:Georgia,serif;color:#222;margin-bottom:32px;\"\u003e\n\n  \u003cdiv style=\"background:#002147;border:1px solid #002147;border-radius:8px;padding:16px 20px;margin-bottom:20px;\"\u003e\n    \u003cp style=\"margin:0 0 6px 0;font-size:13px;letter-spacing:0.08em;text-transform:uppercase;color:#7fa8cc;\"\u003eCatalogue\u003c\/p\u003e\n    \u003cp style=\"margin:0 0 12px 0;font-size:22px;font-weight:bold;color:#ffffff;\"\u003eOrganoboron Compounds\u003c\/p\u003e\n    \u003cp style=\"margin:0;font-size:15px;line-height:1.7;color:#ffffff;\"\u003eHigh-purity organoboron reagents for synthetic chemistry and advanced R\u0026amp;D. Essential building blocks for Suzuki–Miyaura cross-coupling, Miyaura borylation, medicinal chemistry, and materials science applications.\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv style=\"display:grid;grid-template-columns:1fr 1fr;gap:12px;margin-bottom:20px;\"\u003e\n    \u003cdiv style=\"background:#e8e7e2;border:1px solid #c8c7c2;border-radius:8px;padding:16px;\"\u003e\n      \u003cp style=\"margin:0 0 6px 0;font-size:11px;letter-spacing:0.08em;text-transform:uppercase;color:#999;\"\u003eWhat we supply\u003c\/p\u003e\n      \u003cp style=\"margin:0;font-size:13px;color:#555;line-height:1.9;\"\u003eBoronic acids\u003cbr\u003eBoronic acid pinacol esters\u003cbr\u003ePotassium trifluoroborates\u003cbr\u003eMIDA boronates\u003cbr\u003eHeteroaryl boron reagents\u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003cdiv style=\"background:#e8e7e2;border:1px solid #c8c7c2;border-radius:8px;padding:16px;\"\u003e\n      \u003cp style=\"margin:0 0 6px 0;font-size:11px;letter-spacing:0.08em;text-transform:uppercase;color:#999;\"\u003eEvery shipment includes\u003c\/p\u003e\n      \u003cp style=\"margin:0;font-size:13px;color:#555;line-height:1.9;\"\u003eBatch-specific CoA\u003cbr\u003eSDS — EU CLP\/GHS compliant\u003cbr\u003eCommercial invoice\u003cbr\u003eDDP service available worldwide\u003cbr\u003eShipped from Helsinki, Finland\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\n\u003c\/div\u003e","products":[{"product_id":"phenylboronic-acid-cas-98-80-6","title":"Phenylboronic Acid | CAS 98-80-6 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e98-80-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e202-701-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00002103\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eRTECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eCY8575000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=CC=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H7BO2\/c8-7(9)6-4-2-1-3-5-6\/h1-5,8-9H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eHXITXNWTGFUOAU-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e66827\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₇BO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e121.93 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e216–219 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in common polar organic reaction solvents. Solubility increases under basic aqueous conditions through boronate formation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog P\u003csub\u003eow\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1.58 (XLogP3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature in a tightly sealed container in a dry place\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top;\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePhenylboronic acid\u003c\/strong\u003e (benzeneboronic acid, PhB(OH)₂) is the unsubstituted parent of the arylboronic acid family. It serves two main roles: introducing the phenyl group through transition-metal-catalysed C–C and C–heteroatom bond formation, and reversibly binding diols for saccharide recognition, sensing, and boronate protection in carbohydrate and polyol synthesis.\u003c\/p\u003e\n\u003cp\u003eIn the solid state it may contain variable amounts of its cyclic anhydride, phenylboroxine. The acid and boroxine forms re-equilibrate under aqueous\/basic coupling conditions, but batch composition can affect assay, effective stoichiometry, and reproducibility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e Parent arylboronic partner for installing the phenyl group into aryl, heteroaryl, and alkenyl scaffolds; a baseline reagent for evaluating catalyst, ligand, base, solvent, electrophile, boronic-acid speciation, and protodeboronation effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e Transfers the phenyl group to heteroatom nucleophiles under copper-mediated aerobic conditions, giving N-phenyl amines, amides, sulfonamides, carbamates, and N-phenyl heterocycles, plus selected O- and S-phenylated products where the nucleophile and copper system are compatible.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed conjugate addition:\u003c\/strong\u003e 1,4-addition transferring the phenyl group to the β-position of enones, enoates, enamides, and related Michael acceptors; chiral ligands give enantioenriched β-aryl carbonyl products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e Multicomponent reaction with an amine and a carbonyl giving amines bearing phenyl α to nitrogen; glyoxylic acid\/glyoxylates and α-hydroxy aldehydes access α-aryl-α-amino acid derivatives and β-amino-alcohol scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol recognition and saccharide sensing:\u003c\/strong\u003e Reversibly binds cis-1,2- and 1,3-diols in aqueous or mixed solvent to form cyclic boronate esters, used to recognise glucose, fructose, sialic acid, and other cis-diol analytes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoronate ester formation:\u003c\/strong\u003e Forms cyclic esters with 1,2- and 1,3-diols to temporarily mask paired hydroxyls in carbohydrate, polyol, and natural-product synthesis; cleaved by hydrolysis, transesterification, or oxidation where compatible.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e Replaces the boronic acid group with chlorine, bromine, or iodine using electrophilic halogen sources to access phenyl halides or halogenated intermediates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate ester preparation:\u003c\/strong\u003e Precursor to pinacol, neopentyl glycol, and MIDA phenylboronates when a more stable or chromatographically tractable boron building block is needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaterials and functional-molecule synthesis:\u003c\/strong\u003e Phenyl-transfer building block for biaryl and arylated intermediates in materials and functional-molecule R\u0026amp;D.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e Benchmark substrate for boronic acid → phenol conversion under aerobic photoredox, peroxide-mediated, or copper-catalysed conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor further reading: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eBoron reagent selection for Suzuki–Miyaura coupling\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53408011878737,"sku":"NOR-98806-5g","price":19.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53408011911505,"sku":"NOR-98806-10g","price":29.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53408011944273,"sku":"NOR-98806-25g","price":39.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53408011977041,"sku":"NOR-98806-50g","price":64.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53408012009809,"sku":"NOR-98806-100g","price":94.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53408012042577,"sku":"NOR-98806-250g","price":149.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53408012075345,"sku":"NOR-98806-500g","price":269.95,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53408012108113,"sku":"NOR-98806-1000g","price":449.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Phenylboronic_Acid.png?v=1782683270"},{"product_id":"4-methylphenylboronic-acid-cas-5720-05-8","title":"4-Methylphenylboronic Acid | CAS 5720-05-8 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e5720-05-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e611-480-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00039138\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eRTECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eXS7400000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)C)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H9BO2\/c1-6-2-4-7(5-3-6)8(9)10\/h2-5,9-10H,1H3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eBIWQNIMLAISTBV-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e79799\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₉BO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e135.96 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e256–263 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in common polar organic reaction solvents. Solubility increases under basic aqueous conditions through boronate formation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature in a tightly sealed container in a dry place\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Methylphenylboronic Acid\u003c\/strong\u003e (4-tolylboronic acid, p-tolylboronic acid, 4-methylbenzeneboronic acid) contains a para-methyl group, which confers a mildly electron-rich character on the molecule without adding coordination sites, ionisable functionality, or significant steric bulk.\u003c\/p\u003e\n\u003cp\u003eLike many arylboronic acids, 4-methylphenylboronic acid may contain small amounts of the corresponding cyclic anhydride, 4-methylphenylboroxine, in the solid state. Under aqueous\/basic coupling conditions, boronic acid and boroxine forms usually re-equilibrate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e Used as a p-tolyl-transfer reagent for installing the p-tolyl group into aryl, heteroaryl, and alkenyl scaffolds. The methyl substituent gives a compact lipophilic aryl group useful in SAR, materials, and synthetic-methodology work.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e Common partner in copper-mediated C–N, C–O, and selected C–S arylation. It transfers the p-tolyl group to amines, amides, sulfonamides, carbamates, N–H heterocycles, compatible phenols, selected alcohols, and selected sulfur nucleophiles.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed conjugate addition:\u003c\/strong\u003e Participates in 1,4-addition to α,β-unsaturated carbonyl substrates, transferring the p-tolyl group to the β-position of enones, enoates, enamides, nitroalkenes, and related Michael acceptors. Under suitable chiral ligand systems, the reaction can deliver enantioenriched β-(p-tolyl) carbonyl and β-(p-tolyl)nitro products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e Combines with an amine and a carbonyl component in a multicomponent reaction to give substituted amines bearing the p-tolyl group at the α-position to nitrogen. Glyoxylic acid\/glyoxylates and suitable α-hydroxy aldehydes give access to α-(p-tolyl)-α-amino acid derivatives and β-amino-alcohol scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaterials and functional-molecule synthesis:\u003c\/strong\u003e Practical p-tolyl-transfer building block for biaryl and arylated small-molecule intermediates used in materials, ligand, dye, and functional-molecule R\u0026amp;D.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate ester preparation:\u003c\/strong\u003e Precursor for protected 4-methylphenylboronate esters such as pinacol, neopentyl glycol, and MIDA derivatives when a more stable or chromatographically tractable p-tolyl-boron building block is required.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e Can be converted to 4-bromotoluene, 4-chlorotoluene, or 4-iodotoluene under suitable electrophilic halogenation conditions where the boronic acid has served as a directing or coupling handle in earlier steps.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e Substrate for conversion to p-cresol under aerobic photoredox, peroxide-mediated, or copper-catalysed boronic acid → phenol conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol recognition studies:\u003c\/strong\u003e Secondary cis-diol recognition motif in boronate-ester binding studies, with weaker practical sensing value than more acidic or amine-appended boronic acid receptors.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor a broader discussion of boronic acids, boronic esters, protodeboronation risk, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53408896057681,"sku":"NOR-5720058-5g","price":24.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53408896090449,"sku":"NOR-5720058-10g","price":34.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53408896123217,"sku":"NOR-5720058-25g","price":49.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53408896155985,"sku":"NOR-5720058-50g","price":79.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53408896188753,"sku":"NOR-5720058-100g","price":109.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53408896221521,"sku":"NOR-5720058-250g","price":174.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53408896254289,"sku":"NOR-5720058-500g","price":299.95,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53408896287057,"sku":"NOR-5720058-1000g","price":499.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Methylphenylboronic_Acid.png?v=1782683270"},{"product_id":"4-methoxyphenylboronic-acid-cas-5720-07-0","title":"4-Methoxyphenylboronic Acid | CAS 5720-07-0 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border-width: medium 1px 1px; border-style: none solid solid; border-color: currentcolor rgb(228, 232, 240) rgb(228, 232, 240); font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; height: 428.016px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e5720-07-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e611-482-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eMFCD00039139\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eRTECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eCY8975000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); word-break: break-all; height: 18.6094px;\"\u003eB(C1=CC=C(C=C1)OC)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 37.2188px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 37.2188px;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); word-break: break-all; height: 37.2188px;\"\u003eInChI=1S\/C7H9BO3\/c1-11-7-4-2-6(3-5-7)8(9)10\/h2-5,9-10H,1H3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); word-break: break-all; height: 18.6094px;\"\u003eVOAAEKKFGLPLLU-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e201262\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eC₇H₉BO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e151.96 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e204-206 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 37.2188px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 37.2188px;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 37.2188px;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 37.2188px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 37.2188px;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 37.2188px;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 55.8281px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 55.8281px;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 55.8281px;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); height: 18.6094px;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Methoxyphenylboronic Acid\u003c\/strong\u003e (4-anisylboronic acid, p-anisylboronic acid, 4-methoxybenzeneboronic acid) bears a para-methoxy group, a strong resonance donor (+M effect; σp ≈ −0.27). It is used in medicinal-chemistry, agrochemical, natural-product-analogue, and π-conjugated materials synthesis.\u003c\/p\u003e\n\u003cp\u003eLike many arylboronic acids, 4-methoxyphenylboronic acid may contain small amounts of the corresponding cyclic anhydride, 4-methoxyphenylboroxine, in the solid state. Under aqueous\/basic coupling conditions, boronic acid and boroxine forms usually re-equilibrate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e Used with aryl, heteroaryl, or alkenyl electrophiles to prepare p-anisyl-substituted biaryls, heterobiaryls, and aryl–alkene products. The methoxy group gives an electron-rich aryl unit useful in SAR, materials, and synthetic-methodology work.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e Common partner in copper-mediated C–N and C–O arylation. It transfers the p-anisyl group to amines, amides, sulfonamides, carbamates, N–H heterocycles, compatible phenols, and selected alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed conjugate addition:\u003c\/strong\u003e Participates in 1,4-addition to α,β-unsaturated carbonyl substrates, transferring the p-anisyl group to the β-position of enones, enoates, enamides, nitroalkenes, and related Michael acceptors. Suitable chiral ligand systems can give enantioenriched β-(p-anisyl) carbonyl and β-(p-anisyl)nitro products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e Combines with an amine and a carbonyl component in a multicomponent reaction to give substituted amines bearing the p-anisyl group at the α-position to nitrogen. Glyoxylic acid\/glyoxylates and suitable α-hydroxy aldehydes give access to α-(p-anisyl)-α-amino acid derivatives and β-amino-alcohol scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectron-rich materials and functional-molecule synthesis:\u003c\/strong\u003e Practical p-anisyl source for biaryl, aryl-heteroaryl, and arylated small-molecule intermediates used in materials, ligand, dye, natural-product-analogue, and functional-molecule R\u0026amp;D. The p-anisyl unit is a recurring donor fragment in push-pull chromophores, electron-rich π-conjugated systems, and arylated heterocycles.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLatent phenol handle:\u003c\/strong\u003e The methoxy group can undergo demethylation (e.g. BBr3, etc) to generate the corresponding phenol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate ester preparation:\u003c\/strong\u003e Precursor for protected 4-methoxyphenylboronate esters such as pinacol, neopentyl glycol, and MIDA derivatives when a more stable p-anisyl-boron building block s required.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e Can be converted to 4-bromoanisole, 4-chloroanisole, or 4-iodoanisole under suitable electrophilic halogenation conditions where the boronic acid has served as a directing or coupling handle in earlier steps.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e Substrate for conversion to 4-methoxyphenol (mequinol) under aerobic photoredox, peroxide-mediated, or copper-catalysed boronic acid → phenol conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol recognition studies:\u003c\/strong\u003e Secondary cis-diol recognition motif in boronate-ester binding studies. The electron-donating methoxy group tends to raise boronic-acid pKa, so practical glucose\/saccharide sensing is usually weaker than with more acidic or amine-appended boronic acid receptors.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53412078813521,"sku":"NOR-5720070-1g","price":19.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53412078846289,"sku":"NOR-5720070-5g","price":29.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53412078879057,"sku":"NOR-5720070-10g","price":39.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53412078911825,"sku":"NOR-5720070-25g","price":54.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53412078944593,"sku":"NOR-5720070-50g","price":84.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53412078977361,"sku":"NOR-5720070-100g","price":124.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53412079010129,"sku":"NOR-5720070-250g","price":199.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53412079042897,"sku":"NOR-5720070-500g","price":349.95,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53412079075665,"sku":"NOR-5720070-1000g","price":599.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Methoxyphenylboronic_Acid.png?v=1782683270"},{"product_id":"4-fluorophenylboronic-acid-powder-cas-1765-93-1-purity-98","title":"4-Fluorophenylboronic Acid | CAS 1765-93-1 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1765-93-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e605-778-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00039136\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BFO2\/c8-6-3-1-5(2-4-6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eLBUNNMJLXWQQBY-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e285645\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BFO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e139.92 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e262-265 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top;\"\u003e\u003c\/td\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; color: rgb(51, 51, 51);\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Fluorophenylboronic Acid\u003c\/strong\u003e (4-fluorobenzeneboronic acid, \u003cem\u003ep\u003c\/em\u003e-fluorophenylboronic acid) carries a para-fluorine with a modest net electron-withdrawing effect (σp ≈ +0.06): strong −I withdrawal is partly offset by weak +M donation from the fluorine lone pairs. In products derived from this reagent, the aryl C–F tunes lipophilicity, metabolic stability, dipole, conformational preference, π-stacking, and molecular recognition, and provides a built-in 19F NMR handle for tracking the boronic acid, its esters, and its binding partners in solution. It is used as a building block in medicinal chemistry, agrochemicals, natural-product analogues, fluorinated π-conjugated materials, and liquid-crystal precursors.\u003c\/p\u003e\n\u003cp\u003eLike many arylboronic acids, this material may contain small amounts of the corresponding cyclic anhydride, 4-fluorophenylboroxine. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling: \u003c\/strong\u003ewith aryl, heteroaryl, or alkenyl electrophiles to give 4-fluorophenyl-substituted biaryls, heterobiaryls, terphenyls, and styrenyl products. Widely used in SAR work and materials synthesis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated C–N and C–O arylation, transferring the 4-fluorophenyl group to amines, amides, sulfonamides, carbamates, N–H heterocycles, phenols, and selected alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed 1,4-addition:\u003c\/strong\u003e conjugate addition to α,β-unsaturated carbonyls and related activated alkenes. Chiral ligand systems give enantioenriched β-(4-fluorophenyl) carbonyl products; chromone-type acceptors have been reported in good yield and high ee.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component condensation with an amine and a carbonyl partner to give α-aryl amines bearing the 4-fluorophenyl group, under metal-free C–C\/C–N bond-forming conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol recognition and saccharide sensing:\u003c\/strong\u003e forms reversible boronate esters with \u003cem\u003ecis\u003c\/em\u003e-1,2- and 1,3-diols. The mildly electron-withdrawing fluorine lowers the boronic-acid p\u003cem\u003eK\u003c\/em\u003ea relative to phenylboronic acid, improving boronate formation under near-neutral aqueous conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e19F NMR studies: \u003c\/strong\u003ethe aryl fluorine gives distinct 19F chemical shifts for the free boronic acid, the boronate, and the diol ester, allowing each form to be followed directly in solution.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaterials and liquid-crystal precursors:\u003c\/strong\u003e 4-fluorophenyl source for fluorinated biaryl, terphenyl, aryl–heteroaryl, chromophore, ligand, liquid-crystal, and functional-molecule intermediates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation: \u003c\/strong\u003ecoupling with arenediazonium tetrafluoroborates, diaryliodonium salts, and other hypervalent iodine reagents for installation of the 4-fluorophenyl group.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate ester synthesis: \u003c\/strong\u003eprecursor to pinacol (Bpin), neopentyl glycol, and MIDA esters when a more robust 4-fluoroaryl-boron building block is required.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eIpso\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e-halodeboronation:\u003c\/strong\u003e conversion to 1-bromo-4-fluorobenzene, 1-chloro-4-fluorobenzene, or 1-fluoro-4-iodobenzene under appropriate electrophilic halogenation conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e conversion to 4-fluorophenol under aerobic photoredox, peroxide-mediated, or copper-catalysed conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53413207703889,"sku":"NOR-1765931-5g","price":24.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53413207736657,"sku":"NOR-1765931-10g","price":39.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53413207769425,"sku":"NOR-1765931-25g","price":54.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53413207802193,"sku":"NOR-1765931-50g","price":84.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53413207834961,"sku":"NOR-1765931-100g","price":124.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53413207867729,"sku":"NOR-1765931-250g","price":199.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53413207900497,"sku":"NOR-1765931-500g","price":359.95,"currency_code":"EUR","in_stock":true},{"title":"1000 g","offer_id":53413207933265,"sku":"NOR-1765931-1000g","price":599.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Fluorophenylboronic_Acid.png?v=1782683270"},{"product_id":"3-fluorophenylboronic-acid-powder-cas-768-35-4-purity-98","title":"3-Fluorophenylboronic Acid | CAS 768-35-4 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e768-35-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e616-400-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00236042\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC=C1)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BFO2\/c8-6-3-1-2-5(4-6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eKNXQDJCZSVHEIW-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2733986\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BFO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e139.92 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e214-218 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Fluorophenylboronic Acid\u003c\/strong\u003e (3-fluorobenzeneboronic acid, \u003cem\u003em\u003c\/em\u003e-fluorophenylboronic acid) carries a meta-fluorine that is more strongly electron-withdrawing than the para isomer (σm +0.34 vs σp +0.06). The aryl C–F tunes lipophilicity, metabolic stability, dipole, and π-stacking in derived products, and acts as a built-in 19F NMR tracer. Used as a 3-fluorophenyl building block in medicinal chemistry, agrochemicals, fluorinated π-conjugated materials, and liquid-crystal precursors.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 3-fluorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 3-fluorophenyl biaryls, heterobiaryls, terphenyls, and styrenyl products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated C–N and C–O arylation onto amines, amides, sulfonamides, N–H heterocycles, and phenols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed 1,4-addition:\u003c\/strong\u003e conjugate addition to α,β-unsaturated carbonyls; chiral ligands give enantioenriched β-(3-fluorophenyl) products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component coupling with an amine and a carbonyl (glyoxylates, α-hydroxy aldehydes) to give α-aryl amines, α-amino acids, or β-amino alcohols, metal-free.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol recognition and saccharide sensing:\u003c\/strong\u003e reversible boronate esters with \u003cem\u003ecis\u003c\/em\u003e-1,2- and 1,3-diols; lower p\u003cem\u003eK\u003c\/em\u003ea improves binding to saccharides, catechols, and phosphates near neutral pH.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e with arenediazonium salts, diaryliodonium salts, and hypervalent iodine reagents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e19F NMR tracer:\u003c\/strong\u003e the installed 3-fluorophenyl group serves as a 19F reporter for tracking the target molecule in binding studies, metabolism, and complex mixtures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaterials and liquid-crystal precursors:\u003c\/strong\u003e 3-fluorophenyl source for biaryl, terphenyl, chromophore, ligand, and liquid-crystal intermediates, regioisomerically distinct from para-fluoro analogues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, and MIDA esters for iterative cross-coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eIpso\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e-halodeboronation:\u003c\/strong\u003e to 1-bromo-, 1-chloro-, or 1-iodo-3-fluorobenzene under electrophilic halogenation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e to 3-fluorophenol under aerobic photoredox, peroxide, or copper-catalysed conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53413560582481,"sku":"NOR-768354-5g","price":34.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53413560615249,"sku":"NOR-768354-10g","price":49.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53413560648017,"sku":"NOR-768354-25g","price":74.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53413560680785,"sku":"NOR-768354-50g","price":119.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53413560713553,"sku":"NOR-768354-100g","price":179.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53413560746321,"sku":"NOR-768354-250g","price":289.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53413560779089,"sku":"NOR-768354-500g","price":498.95,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53413560811857,"sku":"NOR-768354-1kg","price":829.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Fluorophenylboronic_Acid.png?v=1782683270"},{"product_id":"3-4-difluorophenylboronic-acid-powder-cas-168267-41-2-purity-98","title":"3,4-Difluorophenylboronic Acid | CAS 168267-41-2 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e168267-41-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e605-510-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00807405\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=C(C=C1)F)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H5BF2O2\/c8-5-2-1-4(7(10)11)3-6(5)9\/h1-3,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eRMGYQBHKEWWTOY-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734337\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₅BF₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e157.91 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e289-290 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top;\"\u003e\u003c\/td\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; color: rgb(51, 51, 51);\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3,4-Difluorophenylboronic Acid\u003c\/strong\u003e (3,4-difluorobenzeneboronic acid) carries adjacent fluorines at the 3- and 4-positions: the meta-fluorine contributes strong inductive withdrawal at the boron-bearing carbon, while the para-fluorine adds a weaker net withdrawal. The 3,4-difluorophenyl C–F pair tunes lipophilicity, metabolic stability, dipole, conformational preference, π-stacking, and molecular recognition in derived products, and acts as a built-in 19F NMR tracer. Used as a 3,4-difluorophenyl building block in medicinal chemistry, agrochemicals, fluorinated π-conjugated materials, and liquid-crystal precursors.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 3,4-difluorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 3,4-difluorophenyl biaryls, heterobiaryls, terphenyls, and styrenyl products; reported in fluorinated nucleoside scaffolds, enzyme-inhibitor intermediates, and π-conjugated materials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated C–N and C–O arylation onto amines, amides, sulfonamides, carbamates, N–H heterocycles, and phenols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component coupling with an amine and a carbonyl to give α-aryl amines, α-amino acids, or β-amino alcohols bearing the 3,4-difluorophenyl group, metal-free.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNickel-catalysed aryl transfer to aldehydes:\u003c\/strong\u003e addition to aryl aldehydes giving fluorinated diarylmethanols and access to difluorinated benzhydryl alcohol motifs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiazaborinine formation:\u003c\/strong\u003e condensation with diamines to give conjugated fluorinated diazaborinine systems.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiebeskind–Srogl-type coupling:\u003c\/strong\u003e aryl partner in oxo-directed coupling with α-oxo ketene dithioacetal substrates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSubstitution with enyne derivatives:\u003c\/strong\u003e reported with selected enyne acetates and carbonates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e with arenediazonium salts, diaryliodonium salts, and hypervalent iodine reagents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e19F NMR tracer:\u003c\/strong\u003e the installed 3,4-difluorophenyl group serves as a 19F reporter for tracking the target molecule in binding studies, metabolism, and complex mixtures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaterials and liquid-crystal precursors:\u003c\/strong\u003e 3,4-difluorophenyl source for biaryl, terphenyl, chromophore, ligand, and liquid-crystal intermediates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, and MIDA esters for iterative cross-coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eIpso\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e-halodeboronation:\u003c\/strong\u003e to 4-bromo-, 4-chloro-, or 4-iodo-1,2-difluorobenzene under electrophilic halogenation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e to 3,4-difluorophenol under aerobic photoredox, peroxide, or copper-catalysed conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53416734753105,"sku":"NOR-168267412-1g","price":22.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53416734785873,"sku":"NOR-168267412-5g","price":39.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53416734818641,"sku":"NOR-168267412-10g","price":59.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53416734851409,"sku":"NOR-168267412-25g","price":84.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53416734884177,"sku":"NOR-168267412-50g","price":134.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53416734916945,"sku":"NOR-168267412-100g","price":199.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53416734949713,"sku":"NOR-168267412-250g","price":299.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53416734982481,"sku":"NOR-168267412-500g","price":499.95,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53416735015249,"sku":"NOR-168267412-1kg","price":879.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-4-Difluorophenylboronic_Acid.png?v=1782683270"},{"product_id":"4-chlorophenylboronic-acid-powder-cas-1679-18-1-purity-98","title":"4-Chlorophenylboronic Acid | CAS 1679-18-1 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1679-18-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e216-845-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00039137\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eRTECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eCY8950000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)Cl)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BClO2\/c8-6-3-1-5(2-4-6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eCAYQIZIAYYNFCS-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e74299\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BClO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e156.38 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e284-289 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top;\"\u003e\u003c\/td\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; color: rgb(51, 51, 51);\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Chlorophenylboronic Acid\u003c\/strong\u003e (4-chlorobenzeneboronic acid, \u003cem\u003ep\u003c\/em\u003e-chlorophenylboronic acid) bears a para-chlorine that is moderately electron-withdrawing (σp +0.23), with inductive withdrawal outweighing weak resonance donation, lowering the boronic-acid p\u003cem\u003eK\u003c\/em\u003ea below that of phenylboronic acid (≈ 8.9). The aryl C–Cl bond is also a useful synthetic handle: after installation of the 4-chlorophenyl unit, it can be retained for later Pd- or Ni-catalysed cross-coupling, Buchwald–Hartwig amination, or related aryl chloride chemistry under suitable conditions. Used as a 4-chlorophenyl building block in medicinal chemistry, agrochemicals, functional molecules, and materials intermediates.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-chlorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 4-chlorophenyl biaryls, heterobiaryls, terphenyls, and styrenyl products. The residual aryl chloride can be retained for later diversification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIterative cross-coupling at the chloride handle:\u003c\/strong\u003e the C–Cl bond in 4-chlorophenyl products can be engaged in later Suzuki–Miyaura, Buchwald–Hartwig, or related Pd\/Ni-catalysed reactions when the ligand system and substrate class support aryl chloride activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated C–N and C–O arylation onto amines, amides, sulfonamides, carbamates, N–H heterocycles, phenols, and selected alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component coupling with an amine and a carbonyl partner to give α-aryl amines, α-amino acids, or β-amino alcohols bearing the 4-chlorophenyl group, metal-free.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePd- and Ru-catalysed direct arylation:\u003c\/strong\u003e aryl source in palladium- and ruthenium-catalysed direct arylation and related C–H functionalisation chemistry.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyclopalladation and tandem Pd chemistry:\u003c\/strong\u003e reported in cyclopalladation, Pd-catalysed arylative cyclisation, and tandem Pd(II)-catalysed oxidative Heck \/ intramolecular C–H amidation sequences.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegioselective arylation and alkynylation:\u003c\/strong\u003e reported in Suzuki–Miyaura and Sonogashira-type cross-coupling sequences where the 4-chlorophenyl unit is part of the arylation\/alkynylation design.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, and MIDA esters when a more robust 4-chloroaryl-boron building block is required for staged or iterative synthesis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eIpso\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e-halodeboronation:\u003c\/strong\u003e to 1-bromo-4-chlorobenzene, 1,4-dichlorobenzene, or 1-chloro-4-iodobenzene under electrophilic halogenation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative hydroxylation:\u003c\/strong\u003e to 4-chlorophenol under aerobic photoredox, peroxide, or copper-catalysed conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53416884470097,"sku":"NOR-1679181-5g","price":24.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53416884502865,"sku":"NOR-1679181-10g","price":34.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53416884535633,"sku":"NOR-1679181-25g","price":49.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53416884568401,"sku":"NOR-1679181-50g","price":79.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53416884601169,"sku":"NOR-1679181-100g","price":109.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53416884633937,"sku":"NOR-1679181-250g","price":189.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53416884666705,"sku":"NOR-1679181-500g","price":329.25,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53416884699473,"sku":"NOR-1679181-1kg","price":499.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Chlorophenylboronic_Acid.png?v=1782683270"},{"product_id":"4-bromophenylboronic-acid-powder-cas-5467-74-3-purity-98","title":"4-Bromophenylboronic Acid | CAS 5467-74-3 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e5467-74-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e226-779-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00002104\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eRTECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eCY8650000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)Br)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BBrO2\/c8-6-3-1-5(2-4-6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eQBLFZIBJXUQVRF-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e79599\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BBrO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e200.83 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e284-288 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top;\"\u003e\u003c\/td\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; color: rgb(51, 51, 51);\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Bromophenylboronic Acid\u003c\/strong\u003e (4-bromobenzeneboronic acid, p-bromophenylboronic acid) carries a para-bromine with σp +0.23, essentially matching para-chloro in Hammett electronic terms, and has a measured boronic-acid pKa around 8.2 in water at 25 °C, below phenylboronic acid (≈ 8.9). The aryl C–Br bond is a versatile downstream handle: more reactive than the corresponding aryl chloride in Pd-catalysed cross-coupling, accessible to halogen–metal exchange and magnesium insertion when the boron centre is suitably protected, and an AB-type aryl bromide \/ boronic-acid motif for Suzuki polycondensation or para-phenylene incorporation. Used as a 4-bromophenyl building block in medicinal chemistry, agrochemicals, conjugated materials, organic semiconductors, and polymer synthesis.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-bromophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 4-bromophenyl biaryls, heterobiaryls, terphenyls, and styrenyl products. Selectivity for the boronic acid over the aryl bromide depends on electrophile class and catalyst system; aryl iodide or aryl triflate partners typically allow the C–Br to be retained for later use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIterative cross-coupling at the bromide handle:\u003c\/strong\u003e the C–Br bond can be engaged in subsequent Pd- or Ni-catalysed Suzuki–Miyaura, Buchwald–Hartwig, Negishi, Stille, Sonogashira, or Heck chemistry; relative to aryl chlorides, aryl bromides generally require less forcing oxidative-addition conditions, although catalyst and ligand choice remain coupling-class-dependent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhotoredox \/ nickel dual-catalysis cross-coupling:\u003c\/strong\u003e reported as the aryl bromide partner in Csp³–Csp² coupling with alkyltrifluoroborates; unprotected 4-bromophenylboronic acid is a specific example where the free boronic acid is tolerated as a latent functional group and remains available for subsequent Suzuki–Miyaura chemistry.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIron-catalysed radical arylation of arenes:\u003c\/strong\u003e reported in Fe(OTf)3 \/ 1,10-phenanthroline-mediated oxidative coupling with benzene derivatives using di-tert-butyl peroxide as oxidant; aryl radicals generated from the boronic acid undergo homolytic aromatic substitution to give 4-bromobiaryl products while retaining the para-bromide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHalogen–metal exchange and organomagnesium chemistry:\u003c\/strong\u003e the para-bromide can be converted to aryl-lithium or aryl-magnesium intermediates in protected boronate formats, with pinacol, MIDA, Bdan, or related protected boron derivatives preferred where the boron function must survive; the free boronic acid is not directly compatible with strong organolithium or Grignard conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated C–N and C–O arylation onto amines, amides, sulfonamides, carbamates, N–H heterocycles, phenols, and selected alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component coupling with an amine and a carbonyl partner to give α-aryl amines, α-amino acids, or β-amino alcohols bearing the 4-bromophenyl group, metal-free.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePd-catalysed Heck-type and conjugate addition chemistry:\u003c\/strong\u003e reported in stereoselective Heck-type arylation of allylic esters and Pd(II)-catalysed diastereoselective conjugate addition to activated alkenes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTandem Pd(II) oxidative Heck \/ C–H amidation:\u003c\/strong\u003e reported in tandem-type oxidative Heck arylation followed by intramolecular C–H amidation sequences for heterocycle construction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper-mediated fluoroalkylation:\u003c\/strong\u003e reported in ligandless aerobic Cu-catalysed reactions with fluoroalkyl iodides to give 4-bromo-fluoroalkylarene products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAB-type Suzuki polycondensation:\u003c\/strong\u003e the bifunctional aryl bromide \/ boronic-acid pair makes the molecule an AB-type monomer or capping unit for poly(para-phenylene)-type and related Suzuki-polycondensation architectures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, MIDA, and 1,8-diaminonaphthalene (Bdan) esters. Bdan masking is particularly useful in iterative synthesis, allowing Pd-catalysed reactions at the C–Br bond while the boron centre remains inert until later deprotection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e Suzuki–Miyaura-type coupling with arenediazonium tetrafluoroborates as alternative aryl electrophiles.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e deborylative bromination or iodination of arylboronic acids can replace the boronic-acid group with halogen; for the 4-bromo substrate this provides access to para-dihalogenated benzene motifs such as 1,4-dibromobenzene or 1-bromo-4-iodobenzene, depending on halogen source and conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e peroxide- or perborate-mediated conversion to 4-bromophenol under mild arylboronic-acid hydroxylation conditions; aerobic photoredox and copper-catalysed variants are broader arylboronic-acid method classes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53417061417297,"sku":"NOR-5467743-5g","price":29.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53417061450065,"sku":"NOR-5467743-10g","price":44.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53417061482833,"sku":"NOR-5467743-25g","price":64.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53417061515601,"sku":"NOR-5467743-50g","price":104.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53417061548369,"sku":"NOR-5467743-100g","price":179.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53417061581137,"sku":"NOR-5467743-250g","price":299.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53417061613905,"sku":"NOR-5467743-500g","price":529.95,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53417061646673,"sku":"NOR-5467743-1000g","price":849.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Bromophenylboronic_Acid.png?v=1782683270"},{"product_id":"4-cyanophenylboronic-acid-powder-cas-126747-14-6-purity-98","title":"4-Cyanophenylboronic Acid | CAS 126747-14-6 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e126747-14-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e671-676-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01318968\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)C#N)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H6BNO2\/c9-5-6-1-3-7(4-2-6)8(10)11\/h1-4,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eCEBAHYWORUOILU-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734326\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₆BNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e146.94 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e\u0026gt;350 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog P\u003csub\u003eow\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1.09\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top;\"\u003e\u003c\/td\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; color: rgb(51, 51, 51);\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Cyanophenylboronic Acid\u003c\/strong\u003e (4-cyanobenzeneboronic acid, p-cyanophenylboronic acid, 4-boronobenzonitrile) carries a para-cyano group that is strongly electron-withdrawing (σp +0.66), with inductive (−I) and resonance (−M) effects acting in the same direction to give one of the strongest electron-withdrawing substituents in routine arylboronic-acid chemistry. The strong electron-deficiency gives a reported boronic-acid pKa around 7.7 in water, well below phenylboronic acid (≈ 8.9), changes boronate speciation under Suzuki–Miyaura conditions, and can make base-promoted protodeboronation a more important competing pathway under strongly aqueous-basic conditions. The retained para-cyano group is itself a versatile downstream handle: hydrolysis to 4-substituted benzoic acids, reduction to 4-aminomethyl arenes or 4-substituted benzaldehydes, [3+2] cycloaddition to tetrazoles as carboxylic-acid bioisosteres, and Pinner-type conversion to amidines or imidates. Used as a 4-cyanophenyl building block in medicinal chemistry, agrochemicals, cyanobiphenyl liquid crystals, and electron-poor π-conjugated materials.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-cyanophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 4-cyanobiaryl, 4-cyano-arylheteroaryl, terphenyl, and aryl-alkenyl products. The strong electron-deficiency changes boronate speciation and can make competing protodeboronation more prominent under aqueous-basic conditions; milder bases, partially anhydrous solvent systems, lower temperatures, or boronate-ester forms may be useful where protodeboronation is observed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyano group transformation in coupled products:\u003c\/strong\u003e the retained para-cyano group is a versatile orthogonal handle for downstream chemistry, including hydrolysis to 4-substituted benzoic acids, catalytic or LiAlH4 reduction to 4-aminomethyl arenes, controlled DIBAL-H reduction to 4-substituted benzaldehydes, [3+2] cycloaddition with sodium azide or TMSN3 to tetrazoles as carboxylic-acid bioisosteres, and Pinner-type conversion to amidines, imidates, and orthoesters.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyanobiphenyl liquid crystal synthesis:\u003c\/strong\u003e key arylboronic-acid building block for cyanobiphenyl (CB) and cyanobiphenyl-based dimer liquid crystals through Suzuki–Miyaura cross-coupling with alkylphenyl halides or related partners; the strongly polar para-cyano group provides the dielectric anisotropy that underlies nematic liquid-crystalline behaviour in the cyanobiphenyl family.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyanoaryl acceptor fragments and electron-poor π-systems:\u003c\/strong\u003e useful for installing a strongly electron-withdrawing 4-cyanophenyl unit into donor–acceptor chromophores, polar biaryls, and electron-poor conjugated materials; optical and frontier-orbital effects remain scaffold-dependent and should be evaluated in the final π-system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFullerene functionalisation:\u003c\/strong\u003e reported in ferric perchlorate-promoted reaction of [60]fullerene with arylboronic acids to give fullerenyl boronic esters, with further diol functionalisation to C60-fused dioxane or dioxepane derivatives.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated arylation onto N, O, and S nucleophiles, including amines, amides, sulfonamides, carbamates, N–H heterocycles, phenols, selected alcohols, and thiols; S-arylation gives diaryl sulfides from aryl thiols and aryl alkyl sulfides from aliphatic thiols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component coupling with an amine and a carbonyl partner to give α-aryl amines, α-amino acids, or β-amino alcohols bearing the 4-cyanophenyl group, metal-free.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLigand-free copper-catalysed coupling with nitroarenes:\u003c\/strong\u003e reported in Cu-catalysed coupling of nitroarenes with arylboronic acids to form diaryl ethers, providing a C–O bond-forming route to cyanoaryl ether scaffolds without phosphine-ligand activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRuthenium-catalysed direct arylation:\u003c\/strong\u003e reported for 4-cyanophenyl arylboronate derivatives in Ru-catalysed arylation of benzylic sp³ C–H positions of directed acyclic amines (typically using a 3-substituted pyridyl directing group), giving α-aryl-amine scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, MIDA, and 1,8-diaminonaphthalene (Bdan) esters when more stable or chromatographically tractable 4-cyanoaryl–boron building blocks are required for iterative cross-coupling, particularly given the protodeboronation susceptibility of the free boronic acid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e Suzuki–Miyaura-type coupling with arenediazonium tetrafluoroborates as alternative aryl electrophiles, and reported in base-free Suzuki-type coupling with pentavalent triarylantimony diacetates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e deborylative bromination, chlorination, or iodination of arylboronic acids can replace the boronic-acid group with halogen; for the 4-cyano substrate this gives access to 4-halobenzonitriles such as 4-bromobenzonitrile, 4-chlorobenzonitrile, or 4-iodobenzonitrile, depending on halogen source and conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e peroxide- or perborate-mediated conversion to 4-cyanophenol under mild arylboronic-acid hydroxylation conditions; aerobic photoredox and copper-catalysed variants are broader arylboronic-acid method classes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53417249636689,"sku":"NOR-126747146-1g","price":29.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53417249669457,"sku":"NOR-126747146-5g","price":54.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53417249702225,"sku":"NOR-126747146-10g","price":79.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53417249734993,"sku":"NOR-126747146-25g","price":149.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53417249767761,"sku":"NOR-126747146-50g","price":279.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53417249800529,"sku":"NOR-126747146-100g","price":489.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53417249833297,"sku":"NOR-126747146-250g","price":799.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Cyanophenylboronic_Acid.png?v=1782683270"},{"product_id":"4-trifluoromethylphenylboronic-acid-powder-cas-128796-39-4-purity-98","title":"4-(Trifluoromethyl)phenylboronic Acid | CAS 128796-39-4 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e128796-39-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e603-301-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00151855\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)C(F)(F)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H6BF3O2\/c9-7(10,11)5-1-3-6(4-2-5)8(12)13\/h1-4,12-13H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eALMFIOZYDASRRC-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734389\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₆BF₃O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e189.93 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e245-250 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog P\u003csub\u003eow\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2.44\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-(Trifluoromethyl)phenylboronic Acid\u003c\/strong\u003e (4-(trifluoromethyl)benzeneboronic acid, α,α,α-trifluoro-p-tolylboronic acid, p-(trifluoromethyl)phenylboronic acid) carries a para-trifluoromethyl group that is strongly electron-withdrawing (σp +0.54), with σ-induction and hyperconjugative withdrawal through the C–F bonds the dominant electronic contributions, distinct from halogen substituents that combine inductive withdrawal with resonance donation. The measured boronic-acid pKa is 7.85 in water, well below phenylboronic acid (≈ 8.9), and trifluoromethylphenylboronic-acid isomers have been reported to show high resistance to protodeboronation, distinguishing the para-CF3 substrate from more labile electron-poor arylboronic acids. The CF3 group is robust under typical synthesis conditions and is retained intact in coupled products, where it tunes lipophilicity, polarity, and electronic character of derived molecules; the three equivalent fluorines also provide a strong, sharp 19F NMR reporter for tracking species in solution and in mechanistic studies. Used as a 4-(trifluoromethyl)phenyl building block in medicinal chemistry, agrochemicals, fluorinated π-conjugated materials, and OLED host and emitter intermediates.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-(trifluoromethyl)phenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 4-(trifluoromethyl)biaryl, 4-CF3-arylheteroaryl, terphenyl, and aryl-alkenyl products. The strong electron-withdrawing CF3 group changes boronate speciation, while published trifluoromethylphenylboronic-acid studies report high resistance to protodeboronation; catalyst, base, solvent, and temperature still govern practical coupling performance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCF3 as property modulator in coupled products:\u003c\/strong\u003e the retained para-trifluoromethyl group is robust under many synthetic conditions and is used to tune lipophilicity, polarity, and electronic character in medicinal-chemistry, agrochemical, and materials scaffolds; effects on permeability, conformation, and metabolic stability remain structure-dependent in the final molecule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e19F NMR handle and mechanistic probe:\u003c\/strong\u003e the three equivalent fluorines of the CF3 group give a convenient 19F NMR reporter for the 4-CF3-phenyl unit. 4-(Trifluoromethyl)phenylboronic acid has been used as a 19F NMR probe in mechanistic studies of Pd-catalysed arylboronic-acid self-coupling and transmetalation chemistry.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e copper-mediated arylation onto N and O nucleophiles, including amines, amides, sulfonamides, carbamates, N–H heterocycles, phenols, and selected alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e three-component coupling with an amine and a carbonyl partner to give α-aryl amines, α-amino acids, or β-amino alcohols bearing the 4-(trifluoromethyl)phenyl group, metal-free.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed asymmetric 1,4-addition:\u003c\/strong\u003e reported in Rh-catalysed enantioselective conjugate-addition chemistry of arylboronic acids, transferring the 4-(trifluoromethyl)phenyl group to activated alkene acceptors under chiral ligand control; exact substrate class and ligand choice are method-dependent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePalladium-catalysed direct arylation:\u003c\/strong\u003e reported as the 4-CF3-aryl source in Pd-catalysed direct C–H arylation of arenes and heteroarenes, including site-selective and regioselective protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTandem Pd(II) oxidative Heck \/ C–H amidation:\u003c\/strong\u003e reported in tandem-type Pd(II)-catalysed oxidative Heck arylation followed by intramolecular C–H amidation sequences for heterocycle construction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRuthenium-catalysed direct arylation:\u003c\/strong\u003e reported for 4-(trifluoromethyl)phenyl arylboronate derivatives in Ru-catalysed arylation of benzylic sp³ C–H positions of directed acyclic amines (typically using a 3-substituted pyridyl directing group), giving α-aryl-amine scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePd-catalysed allylation and Cu-catalysed N-arylation:\u003c\/strong\u003e reported in Pd-catalysed direct cross-coupling with allyl alcohols to give allylated 4-(trifluoromethyl)phenyl products, and in N-arylation of imidazoles and amines using copper-exchanged fluorapatite as a heterogeneous catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicrowave-promoted Pd cross-coupling with acid chlorides:\u003c\/strong\u003e reported in microwave-accelerated Pd-catalysed coupling of arylboronic acids with acid chlorides, especially aroyl chlorides, to give 4-(trifluoromethyl)phenyl aryl ketones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluorinated π-conjugated materials:\u003c\/strong\u003e Suzuki–Miyaura building block for installing the 4-CF3-phenyl unit into electron-poor π-conjugated scaffolds, including thiazolo[5,4-d]thiazole derivatives reported for printable-electronics research and patent-reported CF3-substituted anthracene–carbazole architectures such as CF3CzPA. The CF3 group contributes electron-withdrawing character, polarity, and chemical robustness, while device-level optical and transport effects remain scaffold-dependent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, MIDA, and 1,8-diaminonaphthalene (Bdan) esters when more chromatographically tractable 4-(trifluoromethyl)aryl–boron building blocks are required for iterative cross-coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e Suzuki–Miyaura-type coupling with arenediazonium tetrafluoroborates as alternative aryl electrophiles.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-nitration:\u003c\/strong\u003e reported in copper-mediated nitration chemistry of arylboronic acids, replacing the boronic-acid group with nitro to access nitrobenzotrifluoride-type products from the 4-CF3 arylboronic-acid scaffold; other ipso-nitration protocols are also known across the broader arylboronic-acid class.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e deborylative bromination, chlorination, or iodination of arylboronic acids can replace the boronic-acid group with halogen; for the 4-(trifluoromethyl) substrate this gives access to 4-halobenzotrifluorides such as 4-bromobenzotrifluoride, 4-chlorobenzotrifluoride, or 4-iodobenzotrifluoride, depending on halogen source and conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e peroxide- or perborate-mediated conversion to 4-(trifluoromethyl)phenol under mild arylboronic-acid hydroxylation conditions; aerobic photoredox and copper-catalysed variants are broader arylboronic-acid method classes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53417639838033,"sku":"NOR-128796394-1g","price":29.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53417622274385,"sku":"NOR-128796394-5g","price":44.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53417622307153,"sku":"NOR-128796394-10g","price":64.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53417622339921,"sku":"NOR-128796394-25g","price":94.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53417622372689,"sku":"NOR-128796394-50g","price":169.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53417622405457,"sku":"NOR-128796394-100g","price":249.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53417622438225,"sku":"NOR-128796394-250g","price":429.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53417655370065,"sku":"NOR-128796394-500g","price":789.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-_Trifluoromethyl_phenylboronic_Acid.png?v=1782683270"},{"product_id":"2-6-difluorophenylboronic-acid-powder-cas-162101-25-9-purity-98","title":"2,6-Difluorophenylboronic Acid | CAS 162101-25-9 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e162101-25-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e627-874-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00792436\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=C(C=CC=C1F)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H5BF2O2\/c8-4-2-1-3-5(9)6(4)7(10)11\/h1-3,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eDBZAICSEFBVFHL-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734336\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₅BF₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e157.91 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e147-149 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2,6-Difluorophenylboronic Acid\u003c\/strong\u003e (2,6-difluorobenzeneboronic acid, B-(2,6-difluorophenyl)boronic acid) carries fluorine substituents at both ortho positions of the phenyl ring, creating severe steric congestion at the boron centre and a distinctive electronic environment. The measured boronic-acid pKa is 7.37 (spectrophotometric) \/ 7.41 (potentiometric) in water, more acidic than phenylboronic acid (≈ 8.9) but less acidic than the 2,5-difluoro isomer despite carrying two electron-withdrawing fluorines — attributed to formation of only a single intramolecular B–O–H···F hydrogen bond and to steric perturbation of the second ortho-F. Crucially, di-ortho-fluoro substitution accelerates base-promoted protodeboronation: published kinetic studies show that di-ortho-substituted arylboronic acids, including fluorinated examples, can undergo unusually facile base-promoted C–B fission under aqueous-basic conditions, requiring careful selection of catalyst, base, and concentration in cross-coupling. The two ortho-F substituents also bias coupled biaryls toward twisted, non-planar geometries, though the rotational barrier from 2,6-fluoro substitution alone is insufficient for stable atropisomerism at room temperature. Used as a 2,6-difluorophenyl building block in fluorinated π-conjugated materials, organic semiconductors, liquid-crystal intermediates, and pharmaceutical and agrochemical fragment chemistry.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 2,6-difluorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, or alkenyl electrophiles to give 2,6-difluorobiaryl, 2,6-difluoroaryl-heteroaryl, terphenyl, and aryl-alkenyl products. 2,6-Difluorophenylboronic acid is a documented model partner in Suzuki coupling with 4-chloro-3-methylanisole under Buchwald-type Pd precatalyst\/biaryl-phosphine systems. The di-ortho-fluoro substrate is sterically demanding and base-sensitive, so catalyst, ligand, base, solvent, temperature, and concentration are unusually important for suppressing protodeboronation and obtaining productive transmetalation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtodeboronation susceptibility and mitigation:\u003c\/strong\u003e 2,6-disubstituted arylboronic acids are documented to undergo facile base-promoted C–B fission relative to mono- and meta-substituted analogues. Practical mitigations include milder base selection, reduced exposure to strongly aqueous-basic conditions, lower effective boronate concentration, and use of alternative 2,6-difluoroaryl–boron formats such as pinacol boronate, MIDA\/Bdan derivatives, or potassium aryltrifluoroborates; in fluorinated oligophenyl synthesis, potassium 2,6-difluorophenyltrifluoroborate was used to improve coupling performance relative to the free boronic acid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTwisted biaryl geometry in coupling products:\u003c\/strong\u003e the two ortho-F substituents bias the resulting biaryl toward non-planar conformations, with one ring rotated significantly out of plane relative to the partner ring. Atropisomerism — stable axial chirality at room temperature — generally requires additional ortho substituents on the partner ring; on its own, 2,6-difluoro substitution gives twisted but rapidly interconverting conformers in most biaryls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluorinated π-conjugated materials and organic semiconductors:\u003c\/strong\u003e Suzuki–Miyaura building block for selectively fluorinated oligophenyl architectures. In organic-semiconductor research, 2,6-difluorophenylboronic acid was used with 4-bromo-2,6-difluoro-1-iodobenzene to prepare 4-bromo-2,3′,5′,6-tetrafluorobiphenyl by selective coupling at iodine, a key intermediate toward 2,6-difluorinated oligophenyls; related work used potassium 2,6-difluorophenyltrifluoroborate to improve coupling performance in later-stage oligophenyl assembly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquid-crystal fragment chemistry:\u003c\/strong\u003e fluorinated biphenyl and terphenyl cores are widely used in liquid-crystal materials, where fluorine substitution can tune dipole orientation, dielectric anisotropy, birefringence, viscosity, and mesophase behaviour. 2,6-Difluorophenylboronic acid is supplier-listed as a liquid-crystal intermediate, but this should be treated as class\/commercial positioning rather than a specific mesogen-performance claim.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e2,6-Difluorophenyl as property-tuning fragment:\u003c\/strong\u003e the retained 2,6-difluoro pattern is robust under most synthetic conditions and is used to introduce a defined twisted geometry, dipole, and electron-poor character into derived medicinal-chemistry, agrochemical, and materials scaffolds; effects on permeability, conformation, and metabolic stability remain structure-dependent in the final molecule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e19F NMR handle:\u003c\/strong\u003e the two equivalent ortho fluorines give a sharp 19F NMR reporter for the 2,6-difluorophenyl unit, useful for tracking incorporation and following reactions involving this fragment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to pinacol (Bpin), neopentyl glycol, MIDA, and 1,8-diaminonaphthalene (Bdan) esters when more chromatographically tractable and base-stable 2,6-difluoroaryl–boron building blocks are required for iterative cross-coupling — particularly relevant for this substrate given its base-sensitivity in the free boronic-acid form.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e class-level copper-mediated arylation of N, O, and selected S nucleophiles using arylboronic acids; for the 2,6-difluorophenyl substrate, steric congestion and base sensitivity mean conditions should be screened rather than assumed from less hindered arylboronic acids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e class-level three-component coupling of arylboronic acids with an amine and a carbonyl partner to give α-aryl amines, α-amino acids, or β-amino alcohols; the 2,6-difluorophenyl analogue should be treated as a hindered, potentially slower arylboronic-acid partner unless a substrate-specific example is used.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e Suzuki–Miyaura-type coupling of arylboronic acids with arenediazonium tetrafluoroborates is a useful class-level alternative to aryl halide electrophiles; for 2,6-difluorophenylboronic acid, this should be treated as broader arylboronic-acid chemistry unless a substrate-specific example is cited.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e deborylative bromination, chlorination, or iodination can replace the boronic-acid group with halogen across the arylboronic-acid class; for the 2,6-difluoro substrate, this is best framed as potential access to 2,6-difluorohalobenzene motifs rather than a verified application unless a direct substrate example is added.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e peroxide- or perborate-mediated conversion of arylboronic acids to phenols is a broad method class; conversion of 2,6-difluorophenylboronic acid to 2,6-difluorophenol should be treated as class-level ipso-hydroxylation unless a direct example is cited.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53417818882385,"sku":"NOR-162101259-1g","price":19.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53417818915153,"sku":"NOR-162101259-5g","price":34.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53417818947921,"sku":"NOR-162101259-10g","price":59.2,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53417818980689,"sku":"NOR-162101259-25g","price":109.2,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53417819013457,"sku":"NOR-162101259-50g","price":198.2,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53417819046225,"sku":"NOR-162101259-100g","price":364.9,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53417819078993,"sku":"NOR-162101259-250g","price":689.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53417819111761,"sku":"NOR-162101259-500g","price":1149.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_2-6-Difluorophenylboronic_Acid.png?v=1782683270"},{"product_id":"4-nitrophenylboronic-acid-powder-cas-24067-17-2","title":"4-Nitrophenylboronic Acid | CAS 24067-17-2 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e24067-17-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e627-647-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00161360\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)[N+](=O)[O-])(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BNO4\/c9-7(10)5-1-3-6(4-2-5)8(11)12\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eNSFJAFZHYOAMHL-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2773552\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BNO₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e166.93 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e285-290 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog P\u003csub\u003eow\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e0.96\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003ePale yellow to yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Nitrophenylboronic Acid\u003c\/strong\u003e (4-nitrobenzeneboronic acid, \u003cem\u003ep\u003c\/em\u003e-nitrophenylboronic acid) is a highly electron-deficient arylboronic acid generally used as a building block in medicinal chemistry, agrochemical development, and the synthesis of electron-poor π-conjugated materials. The presence of the \u003cem\u003epara\u003c\/em\u003e-nitro group strongly withdraws electron density from both the aromatic ring and the boronic-acid center (σp = +0.78). This extreme electron withdrawal gives the compound an unusually low pKa of approximately 7.1—well below that of standard phenylboronic acid (≈ 8.8)—ensuring that substantial boronate fraction exists even at near-neutral pH. Notably, while it possesses high Lewis acidity, its rate of protodeboronation is dictated by the full substitution pattern rather than pKa alone. Beyond its role as an aryl-transfer reagent, the nitro group provides a valuable orthogonal handle post-coupling; it can be readily reduced to an aniline derivative, unlocking a vast array of downstream transformations via diazonium chemistry.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-nitrophenylboroxine. Under aqueous or basic coupling conditions, the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e with aryl, heteroaryl, and alkenyl electrophiles to give 4-nitrobiaryls and related products. Ligand-free Pd-catalysed protocols are reported.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNitro group transformations:\u003c\/strong\u003e the para-nitro group is an orthogonal handle on the coupled biaryl. Catalytic hydrogenation or chemical reduction (Sn\/HCl, Fe\/HCl, Zn, SnCl2) gives the 4-aminobiaryl; partial reduction gives nitroso, hydroxylamine, or azo intermediates. The aniline allows accessing Sandmeyer chemistry — halides, phenols, cyanides, fluorides (Balz–Schiemann), azides, and arenes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLewis acidity and Hammett reference:\u003c\/strong\u003e σp(NO2) = +0.78 and pKa ≈ 7.1 place 4-nitrophenylboronic acid at the electron-poor end of common arylboronic acids — useful for comparing substituent effects on ionisation. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich:\u003c\/strong\u003e metal-free three-component coupling with amine and carbonyl partners gives α-(4-nitrophenyl) amines, amino acids, or β-amino alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed 1,4-addition:\u003c\/strong\u003e a heterogeneous Rh-grafted hydrotalcite catalyst performs achiral 1,4-addition of organoboron reagents to electron-deficient olefins. Homogeneous chiral Rh systems with chiral diene or BINAP ligands extend the same chemistry to enantioselective conjugate addition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePalladium-catalysed direct arylation:\u003c\/strong\u003e the 4-nitroaryl source in Pd-catalysed C–H arylation of arenes and heteroarenes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTandem Pd sequence:\u003c\/strong\u003e regioselective Suzuki–Miyaura followed by tandem Pd(II) intramolecular aminocarbonylation\/annulation, giving N-heterocycles with a 4-nitroaryl substituent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRuthenium-catalysed direct arylation:\u003c\/strong\u003e reported for benzylic sp3 C–H arylation of acyclic amines using a pyridyl directing group, giving α-(4-nitroaryl) amines.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper-catalysed Chan–Lam N-arylation of ureas:\u003c\/strong\u003e Cu(acac)2-catalysed N-arylation of phenylurea and related ureas, giving 4-nitroaryl ureas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper-mediated cyanation:\u003c\/strong\u003e Cu-mediated conversion of arylboronic acids to aryl nitriles. For this substrate, gives 4-nitrobenzonitrile — a precursor to tetrazoles, amidines, and primary amides.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegioselective glycosylation of unprotected sugars:\u003c\/strong\u003e Tanaka and co-workers report 4-nitrophenylboronic acid as a catalyst for regio- and 1,2-cis-stereoselective SNi-type glycosylation of 1,2-anhydro donors with unprotected sugar acceptors in water. Reversible boronate formation with cis-diols on the acceptor directs the glycosylation site — the compound acts as a diol-recognition catalyst rather than as an aryl-transfer reagent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to Bpin, neopentyl glycol, MIDA, and Bdan esters for iterative cross-coupling and easier chromatography.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e coupling with arenediazonium tetrafluoroborates as alternative aryl electrophiles.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e arylboronic-acid halodeboronation methods can replace B(OH)2with Br, Cl, or I, giving access to para-halonitrobenzene motifs such as 4-bromo-, 4-chloro-, or 4-iodonitrobenzene depending on the halogen source and conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e peroxide or perborate gives 4-nitrophenol under mild conditions; Cu\/aerobic and Fe-mediated variants offer alternative oxidants.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53418114613585,"sku":"NOR-24067172-1g","price":31.95,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53418114646353,"sku":"NOR-24067172-2g","price":47.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53418114679121,"sku":"NOR-24067172-5g","price":87.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53418114711889,"sku":"NOR-24067172-10g","price":144.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53418114744657,"sku":"NOR-24067172-25g","price":334.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53418114777425,"sku":"NOR-24067172-50g","price":604.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53418114810193,"sku":"NOR-24067172-100g","price":1119.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Nitrophenylboronic_Acid.png?v=1782683270"},{"product_id":"products-3-nitrophenylboronic-acid-powder-cas-13331-27-6-purity-98","title":"3-Nitrophenylboronic Acid | CAS 13331-27-6 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e13331-27-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e603-734-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00007193\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eRTECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eCY8980000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC=C1)[N+](=O)[O-])(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BNO4\/c9-7(10)5-2-1-3-6(4-5)8(11)12\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eZNRGSYUVFVNSAW-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1677\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BNO₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e166.93 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e284-285 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eOff-White pale to yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Nitrophenylboronic Acid\u003c\/strong\u003e (3-nitrobenzeneboronic acid, m-nitrophenylboronic acid, m-nitrobenzeneboronic acid) is a strongly electron-poor arylboronic acid generally used as a building block in medicinal chemistry, agrochemical development, and the synthesis of electron-poor π-conjugated materials. The meta-nitro group is strongly electron-withdrawing (σm = +0.71) and lowers the boronic-acid pKa to an estimated 7.1–7.3 in water. \u003c\/p\u003e\n\u003cp\u003eThis compound may contain small amounts of the cyclic anhydride 3-nitrophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, and alkenyl electrophiles to give 3-nitrobiaryls and related products. Ligand-free Pd-catalysed Suzuki–Miyaura protocols are reported.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNitro group transformations:\u003c\/strong\u003e the meta-nitro group remains an orthogonal handle after coupling. Catalytic hydrogenation or chemical reduction (Sn\/HCl, Fe\/HCl, Zn, SnCl2) gives the 3-aminobiaryl; controlled partial reduction gives nitroso, hydroxylamine, or azo intermediates. The aniline can then be further used in Sandmeyer-type reactions to give halides, phenols, cyanides, fluorides (Balz–Schiemann), azides, and arylated products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol and polyol recognition:\u003c\/strong\u003e 3-nitrophenylboronic acid is a well-studied model substrate for arylboronic-acid–diol complexation. Ishihara and co-workers measured the reactions of both the trigonal acid and tetrahedral boronate forms with ethylene and propylene glycols, showing that the trigonal acid reacts at least 103 times faster than the boronate. Later work used the same compound with alizarin red S to build a general mechanism for boronic acid–diol condensation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLewis-acid catalysis:\u003c\/strong\u003e Dixon and co-workers introduced 3-nitrophenylboronic acid as the Lewis-acid catalyst for ene carbocyclisation of acetylenic 1,3-dicarbonyl compounds, giving five- and six-membered carbocycles from ketoester substrates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapillary electrophoresis probe for sugar alcohols:\u003c\/strong\u003e Britz-McKibbin and co-workers used 3-nitrophenylboronic acid as an electrokinetic probe in capillary electrophoresis. Dynamic complexation with neutral polyols forms anionic boronate ester complexes during electromigration, allowing simultaneous separation and UV detection of sugar alcohol stereoisomers in phosphate buffer.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNanoparticle-enhanced alizarin carbohydrate assay:\u003c\/strong\u003e 3-nitrophenylboronic acid forms reporter complexes with alizarin dyes for saccharide sensing. Crosslinked polymer nanoparticles enhance fluorescence from the 3-nitrophenylboronic acid–alizarin system and improve sensitivity and dynamic range in separation-free assays for glucose and fructose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemoselective H2O2 probe chemistry:\u003c\/strong\u003e nitrophenylboronic-acid isomers, including the 3-nitro compound, react with hydrogen peroxide under alkaline conditions to give yellow nitrophenolates. This reaction supports colorimetric peroxide detection in food and agricultural samples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper-catalysed arylation of indolin-2,3-diones:\u003c\/strong\u003e Cu(OTf)2\/1,10-phenanthroline catalyses arylation of indolin-2,3-diones (isatin derivatives) with 3-nitrophenylboronic acid, giving 3-(3-nitroaryl)-3-hydroxy-2-oxindoles under air.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich:\u003c\/strong\u003e arylboronic acids undergo metal-free three-component coupling with amines and carbonyl partners to give α-aryl amines, α-amino acids, or β-amino alcohols. The 3-nitrophenyl group can be used where the selected Petasis conditions tolerate electron-poor arylboronic acids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther palladium-catalysed couplings:\u003c\/strong\u003e 3-nitrophenylboronic acid is reported in Pd-catalysed decarboxylative coupling and in oxidative arylation\/carbocyclisation chemistry. In the oxidative carbocyclisation case, the 3-nitroaryl group is introduced during ring formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium-catalysed addition to arylpropargyl alcohols:\u003c\/strong\u003e a Rh\/BINAP system catalyses regio- and stereoselective addition of arylboronic acids to arylpropargyl alcohols, transferring the 3-nitrophenyl group across the alkyne to give trisubstituted allylic alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e precursor to Bpin, neopentyl glycol, MIDA, and Bdan esters for iterative cross-coupling and easier chromatography.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation:\u003c\/strong\u003e arylboronic acids can couple with arenediazonium tetrafluoroborates as alternative aryl electrophiles; reaction conditions determine suitability for the 3-nitrophenyl variant.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e arylboronic-acid halodeboronation methods can replace B(OH)2 with Br, Cl, or I, giving access to 3-halonitrobenzene motifs depending on the halogen source and conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e peroxide or perborate converts arylboronic acids to phenols and can give 3-nitrophenol from the 3-nitro substrate; Cu\/aerobic and Fe-mediated variants offer alternative oxidants\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"2.0 g","offer_id":53421249626449,"sku":"NOR-13331276-2g","price":23.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53421249659217,"sku":"NOR-13331276-5g","price":32.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53421249691985,"sku":"NOR-13331276-10g","price":45.2,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53421249724753,"sku":"NOR-13331276-25g","price":89.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53421249757521,"sku":"NOR-13331276-50g","price":164.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53421249790289,"sku":"NOR-13331276-100g","price":299.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53421249823057,"sku":"NOR-13331276-250g","price":684.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53421249855825,"sku":"NOR-13331276-500g","price":1284.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Nitrophenylboronic_Acid.png?v=1782683270"},{"product_id":"2-fluoropyridine-5-boronic-acid-powder-cas-351019-18-6-purity-98","title":"2-Fluoropyridine-5-boronic Acid | CAS 351019-18-6 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e351019-18-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e627-412-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD03411559\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CN=C(C=C1)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C5H5BFNO2\/c7-5-2-1-4(3-8-5)6(9)10\/h1-3,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eOJBYZWHAPXIJID-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2783397\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₅H₅BFNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e140.91 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e172 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog P\u003csub\u003eow\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e0.994\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2-Fluoropyridine-5-boronic Acid\u003c\/strong\u003e (6-fluoropyridine-3-boronic acid, 6-fluoro-3-pyridinylboronic acid, 2-fluoro-5-pyridylboronic acid) is an electron-deficient heteroaryl boronic acid generally used as a fluorinated pyridyl building block in medicinal-chemistry, agrochemical, and fine-chemical synthesis. The boronic-acid group is away from the nitrogen, so the compound is relatively less prone to undergo rapid protodeboronation than other compounds featuring the 2-pyridylboronic-acid motif.\u003c\/p\u003e\n\u003cp\u003eThis compound may contain small amounts of the cyclic anhydride (boroxine); which have a minor impact on the yield of its subsequent reactions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydroxydeboronation to fluorohydroxypyridines:\u003c\/strong\u003e aqueous hydrogen peroxide or mCPBA replaces the B(OH)2 group with hydroxyl and retains the C–F bond, giving 2-fluoro-5-hydroxypyridine (6-fluoropyridin-3-ol). Rault and co-workers reported this transformation for halopyridinylboronic acids and esters under mild conditions, regioselectively and without N-oxide formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, vinyl, and alkenyl electrophiles to give 2-fluoro-5-aryl-, 2-fluoro-5-heteroaryl-, and alkenyl-substituted pyridines. As with other pyridylboronic acids, the pyridine nitrogen can interact with transition-metal catalysts, so palladium source, ligand, base, solvent, and coupling partner strongly affect performance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAromatic SNAr at the 2-position:\u003c\/strong\u003e the ring nitrogen activates the C–F bond at C2 toward aromatic nucleophilic substitution. Amines, alkoxides, phenoxides, thiolates, amides, hydrazines, and stabilised carbanions can displace fluoride under suitable conditions, giving 2-amino-, 2-alkoxy-, 2-thio-, and 2-carbon-substituted pyridines from the coupled product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected and masked boron variants:\u003c\/strong\u003e the pinacol ester is commercially available (CAS 444120-95-0). Molander and co-workers reported potassium 6-fluoropyridin-3-yltrifluoroborate as a bench-stable Suzuki partner; in their substrate scope, it coupled more efficiently with 4-chlorobenzonitrile than with 4-bromobenzonitrile.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"2.0 g","offer_id":53421533757777,"sku":"NOR-351019186-2g","price":27.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53421533790545,"sku":"NOR-351019186-5g","price":39.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53421533823313,"sku":"NOR-351019186-10g","price":59.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53421533856081,"sku":"NOR-351019186-25g","price":124.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53421539000657,"sku":"NOR-351019186-50g","price":219.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53421533888849,"sku":"NOR-351019186-100g","price":404.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53421533921617,"sku":"NOR-351019186-250g","price":924.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53421533954385,"sku":"NOR-351019186-500g","price":1735.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_2-Fluoropyridine-5-boronic_Acid.png?v=1782683270"},{"product_id":"ferroceneboronic-acid-powder-cas-12152-94-2-purity-95","title":"Ferroceneboronic Acid | CAS 12152-94-2 | ≥95%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e12152-94-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e235-272-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00059074\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C[CH-]1)(O)O.[CH-]1C=CC=C1.[Fe+2]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C5H6BO2.C5H5.Fe\/c7-6(8)5-3-1-2-4-5;1-2-4-5-3-1;\/h1-4,7-8H;1-5H;\/q2*-1;+2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eXCHXIPVWFCEEMB-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e82949\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₀H₁₁BFeO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e229.85 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e145-150 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in ether\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥95%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eYellow to orange crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at 2-8 °C. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003eFerroceneboronic Acid\u003c\/strong\u003e ((dihydroxyboryl)ferrocene, ferrocenyl boronic acid, (boronocyclopentadienyl)cyclopentadienyl iron) is a redox-active organometallic boronic acid used in Suzuki cross-coupling, electrochemical saccharide and diol sensing, cyclic-boronate derivatisation, and the synthesis of ferrocene-appended macrocycles. The electron-rich and sterically demanding ferrocenyl group features a reversible Fe(II)\/Fe(III) redox couple that remains intact post-coupling, endowing the target molecule with a built-in electrochemical handle rarely found in standard boronic-acid building blocks. The boronic acid forms cyclic esters with 1,2- and 1,3-diols, which is the basis of saccharide-sensing electrochemistry and of cyclic-boronate diol derivatisation in GC\/MS and HPLC.\u003c\/p\u003e\n\u003cp\u003eThe product may contain small amounts of the cyclic anhydride ferroceneboroxine; under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl and heteroaryl halides and triflates to install the ferrocenyl group on organic scaffolds. The reaction tolerates electron-rich, electron-poor, and heteroaryl partners; cyclic voltammetry of the products tracks how each new substituent shifts the ferrocene oxidation potential.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrochemical saccharide and diol sensors:\u003c\/strong\u003e reversible cyclic boronate ester formation with 1,2- and 1,3-diols shifts the ferrocenyl Fe(II)\/Fe(III) redox potential. This signal-transduction principle has been used to build amperometric and cyclic-voltammetric sensors for fructose, glucose, and other cis-diol analytes; mono-, bis-, and chiral ferroceneboronic-acid derivatives have been developed on this basis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyclic boronate derivatisation for GC\/MS and HPLC:\u003c\/strong\u003e ferroceneboronic acid reacts with vicinal diols and polyols to form cyclic boronate derivatives. This chemistry has been applied in GC\/MS derivatisation and in HPLC with electrochemical detection, where the ferrocenyl unit provides the electroactive label; the determination of brassinosteroids in plant samples is one established example.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFerrocene-appended porphyrins and subporphyrins:\u003c\/strong\u003e Suzuki coupling with halogenated porphyrin or subporphyrin precursors gives ferrocenyl macrocycles studied for optical absorption, fluorescence quenching, electronic communication, and reversible ferrocene-centred oxidation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected and masked boron variants:\u003c\/strong\u003e ferroceneboronic acid has been converted into protected ferrocenylboron derivatives including FcB(dan), FcB(aam), FcBF3K, FcB(MIDA), and triolborate variants, providing better-defined and more easily handled ferrocenylboron reagents for further organometallic synthesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53423205024081,"sku":"NOR-12152942-1g","price":101.95,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53423205056849,"sku":"NOR-12152942-2g","price":189.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53423205089617,"sku":"NOR-12152942-5g","price":429.5,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53423205122385,"sku":"NOR-12152942-10g","price":719.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Ferroceneboronic_Acid.png?v=1782683270"},{"product_id":"3-methoxyphenylboronic-acid-powder-cas-10365-98-7-purity-98","title":"3-Methoxyphenylboronic Acid | CAS 10365-98-7 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border-width: medium 1px 1px; border-style: none solid solid; border-color: currentcolor rgb(228, 232, 240) rgb(228, 232, 240); font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; height: 409.407px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e10365-98-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e600-467-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eMFCD00039111\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); word-break: break-all; height: 18.6094px;\"\u003eB(C1=CC(=CC=C1)OC)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 37.2188px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 37.2188px;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); word-break: break-all; height: 37.2188px;\"\u003eInChI=1S\/C7H9BO3\/c1-11-7-4-2-3-6(5-7)8(9)10\/h2-5,9-10H,1H3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); word-break: break-all; height: 18.6094px;\"\u003eNLLGFYPSWCMUIV-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e2734370\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eC₇H₉BO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e151.96 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e160–163 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 37.2188px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 37.2188px;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 37.2188px;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 37.2188px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 37.2188px;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 37.2188px;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eWhite to light beige crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 18.6094px;\"\u003eRetest period: 36 months from date of manufacture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 55.8281px;\"\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; border-bottom: 1px solid rgb(228, 232, 240); background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 55.8281px;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); border-bottom: 1px solid rgb(228, 232, 240); height: 55.8281px;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6094px;\"\u003e\n\u003ctd style=\"padding-top: 9px; padding-right: 16px; padding-bottom: 9px; font-weight: 600; color: rgb(0, 33, 71); width: 200px; background: rgb(247, 248, 251); font-size: 0.95em; vertical-align: top; height: 18.6094px;\"\u003e\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: rgb(51, 51, 51); height: 18.6094px;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Methoxyphenylboronic Acid\u003c\/strong\u003e (\u003cem\u003em\u003c\/em\u003e-anisylboronic acid, \u003cem\u003em\u003c\/em\u003e-methoxybenzeneboronic acid) is an arylboronic acid often used in medicinal-chemistry, agrochemical, and fine-chemical synthesis. At the \u003cem\u003emeta\u003c\/em\u003e position, the methoxy group does not donate electron density to the boronic-acid-bearing carbon by resonance; its net Hammett effect is weakly electron-withdrawing (σm ≈ +0.12), giving a boronic-acid pKa estimated near 8.5 and close to phenylboronic acid. After cross-coupling, the methoxy substituent can serve as a masked phenol, allowing later access to 3-hydroxyaryl products.\u003c\/p\u003e\n\u003cp\u003eThe product may contain small amounts of the cyclic anhydride 3-methoxyphenylboroxine; under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, vinyl, and alkenyl electrophiles to give 3-methoxybiaryls and related aryl-substituted products. The meta-methoxy group is usually carried through the coupling as an intact aryl ether, which makes the reagent useful for installing a masked 3-hydroxyphenyl motif on the coupled scaffold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethoxy-to-phenol unmasking:\u003c\/strong\u003e after coupling, the methoxy ether on the 3-methoxybiaryl can be cleaved by BBr3, AlCl3, or thiolate-based demethylation to give the 3-hydroxybiaryl. The free phenol can be alkylated or acylated, or converted to an aryl sulfonate such as a triflate for subsequent C–C or C–N cross-coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRh-catalysed conjugate addition:\u003c\/strong\u003e 3-methoxyphenylboronic acid has been used as the aryl donor in rhodium-catalysed asymmetric 1,4-addition to β-aryl-α,β-unsaturated ketones and tert-butyl cinnamate-type esters. Under [Rh(nbd)2]BF4\/(S,S)-chiraphos catalysis, the 3-methoxyphenyl group is transferred to the β-carbon to give enantioenriched β-diaryl carbonyl products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e aqueous hydrogen peroxide under basic conditions can replace B(OH)2 with hydroxyl at the same carbon to give 3-methoxyphenol. This route is distinct from methoxy-to-phenol unmasking: ipso-hydroxylation cleaves the C–B bond on the boronic acid itself, while demethylation cleaves the methyl ether on a coupled product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam N\/O arylation:\u003c\/strong\u003e arylboronic acids can undergo copper-mediated oxidative coupling with N- and O-nucleophiles under air. The 3-methoxyphenyl analogue may be used where the selected Chan–Lam method tolerates anisylboronic acids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich:\u003c\/strong\u003e arylboronic acids can participate in metal-free three-component coupling with amines and carbonyl partners to give α-aryl amines, α-amino acids, or β-amino alcohols. Use of the 3-methoxyphenyl analogue depends on the chosen Petasis method and substrate set.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e organoboron halodeboronation methods can replace B(OH)2 with Br, Cl, or I, providing a route to meta-haloanisole motifs (3-bromoanisole, 3-chloroanisole, 3-iodoanisole) when the substrate and halogenation method are compatible. This complements classical electrophilic aromatic substitution of anisole, where the methoxy group favours \u003cem\u003eortho\u003c\/em\u003e\/\u003cem\u003epara\u003c\/em\u003e substitution.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53429587902801,"sku":"NOR-10365987-5g","price":21.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53429587935569,"sku":"NOR-10365987-10g","price":34.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53429587968337,"sku":"NOR-10365987-25g","price":54.2,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53429588001105,"sku":"NOR-10365987-50g","price":98.2,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53429588033873,"sku":"NOR-10365987-100g","price":179.2,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53429588066641,"sku":"NOR-10365987-250g","price":329.2,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53429588099409,"sku":"NOR-10365987-500g","price":579.2,"currency_code":"EUR","in_stock":true},{"title":"1 kg","offer_id":53429588132177,"sku":"NOR-10365987-1000g","price":995.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Methoxyphenylboronic_Acid.png?v=1782683321"},{"product_id":"3-cyanophenylboronic-acid-powder-cas-150255-96-2-purity-98","title":"3-Cyanophenylboronic Acid | CAS 150255-96-2 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e150255-96-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e604-729-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01318967\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC=C1)C#N)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H6BNO2\/c9-5-6-2-1-3-7(4-6)8(10)11\/h1-4,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eXDBHWPLGGBLUHH-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734325\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₆BNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e146.94 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e298 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Cyanophenylboronic Acid\u003c\/strong\u003e (3-cyanobenzeneboronic acid, \u003cem\u003em\u003c\/em\u003e-cyanophenylboronic acid, 3-boronobenzonitrile) is an electron-poor arylboronic acid. The \u003cem\u003emeta\u003c\/em\u003e-cyano group is strongly electron-withdrawing (Hammett σm ≈ +0.56), lowering the boronic-acid pKa to an estimated value near 7.6 against the parent phenylboronic-acid pKa of 8.76.\u003c\/p\u003e\n\u003cp\u003eThe product may contain small amounts of the cyclic anhydride 3-cyanophenylboroxine; under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl and heteroaryl halides under matched Pd\/phosphine\/base conditions to give 3-cyanobiaryl and 3-cyanoaryl–heteroaryl products. The nitrile substituent is generally compatible with Suzuki conditions and remains intact on the coupled scaffold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyano group as a latent functional handle:\u003c\/strong\u003e after coupling, the \u003cem\u003emeta\u003c\/em\u003e-CN group on the biaryl product can be converted to tetrazoles (NaN3 \/ Zn salts under Sharpless–Demko conditions), to carboxylic acids by hydrolysis, to arylmethylamines by catalytic reduction, or to amidoximes and 1,2,4-oxadiazoles via hydroxylamine-derived intermediates. This makes the reagent useful where a compact polar group is needed during coupling but a different functionality is desired later in the sequence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhenylimidazole-based Ir(III) complexes for blue PhOLED research:\u003c\/strong\u003e 3-cyanophenylboronic acid is used to prepare cyanoaryl-substituted phenylimidazole ligands for cyclometalated Ir(III) complexes. The electron-withdrawing cyanoaryl substituent modifies the electronic structure and emission behaviour of the resulting complexes, supporting their use in phosphorescent blue OLED materials research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiaryl phenylalanine amino-acid analogues:\u003c\/strong\u003e Suzuki coupling with halogenated phenylalanine derivatives, in solution or on solid support, gives \u003cem\u003emeta\u003c\/em\u003e-cyanoaryl-substituted biaryl phenylalanines that retain the nitrile for later polar-group diversification on the coupled framework.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e4-Aryl-1,8-naphthyridin-2(1\u003c\/strong\u003e\u003cstrong\u003e\u003cem\u003eH\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e)-one synthesis:\u003c\/strong\u003e Suzuki coupling with 4-halo-1,8-naphthyridin-2(1\u003cem\u003eH\u003c\/em\u003e)-one precursors gives 4-(\u003cem\u003emeta\u003c\/em\u003e-cyanoaryl)-1,8-naphthyridin-2(1\u003cem\u003eH\u003c\/em\u003e)-ones for heterocyclic scaffold synthesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53429850505553,"sku":"NOR-150255962-1g","price":24.95,"currency_code":"EUR","in_stock":true},{"title":"5.0g","offer_id":53429850538321,"sku":"NOR-150255962-5g","price":44.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53429850571089,"sku":"NOR-150255962-10g","price":79.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53429850603857,"sku":"NOR-150255962-25g","price":129.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53429850636625,"sku":"NOR-150255962-50g","price":209.2,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53429850669393,"sku":"NOR-150255962-100g","price":379.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53429850702161,"sku":"NOR-150255962-250g","price":650.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Cyanophenylboronic_Acid.png?v=1782683321"},{"product_id":"3-bromophenylboronic-acid-powder-cas-89598-96-9-purity-97","title":"3-Bromophenylboronic Acid | CAS 89598-96-9 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e89598-96-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e677-281-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00239386\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC=C1)Br)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BBrO2\/c8-6-3-1-2-5(4-6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eAFSSVCNPDKKSRR-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734318\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BBrO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e200.83 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e164-168 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Bromophenylboronic Acid\u003c\/strong\u003e (3-bromobenzeneboronic acid, m-bromophenylboronic acid) is a bifunctional arylboronic acid carrying both a boronic acid and an aryl bromide at meta positions on the same ring. The meta-Br is inductively electron-withdrawing (Hammett σₘ ≈ +0.39). The estimated pKa is ≈ 8.0, below the parent phenylboronic acid (8.76). The boronic acid is the nucleophilic coupling handle and the aryl bromide the electrophilic one. The two react under different conditions and can be cross-coupled to separate partners in sequential steps.\u003c\/p\u003e\n\u003cp\u003eThe product may contain small amounts of the cyclic anhydride 3-bromophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling at the boronic acid:\u003c\/strong\u003e couples with aryl and heteroaryl electrophiles to install a meta-bromoaryl group on the coupled scaffold. When the aryl bromide is intended for later use, catalyst and electrophile are chosen to avoid premature oxidative addition at the retained Ar–Br bond.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIterative cross-coupling using the retained aryl bromide:\u003c\/strong\u003e the meta-Ar–Br in a Suzuki product can be used in a second Pd-catalysed cross-coupling. In the reverse sequence, the boronic acid can first be masked as its anthranilamide (AAM) boronate; the AAM-protected boronyl group is inactive under Suzuki conditions, allowing coupling at the aryl bromide before deprotection reveals the boronic acid for the next step.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRh-catalysed asymmetric 1,4-addition:\u003c\/strong\u003e under Hayashi–Miyaura-type Rh(I)\/chiral ligand catalysis, 3-bromophenylboronic acid serves as the aryl donor in conjugate addition to α,β-unsaturated ketones, giving enantioenriched β-(3-bromoaryl) carbonyl products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGold-salt-catalysed homocoupling:\u003c\/strong\u003e gold-catalysed homocoupling of arylboronic acids provides symmetrical biaryls; for 3-bromophenylboronic acid this gives access to the corresponding 3,3'-dibromobiphenyl framework from a single boronic-acid reagent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eC–H functionalisation of quinones:\u003c\/strong\u003e under catalytic AgNO₃ with K₂S₂O₈ as oxidant at room temperature, 3-bromophenylboronic acid arylates quinone C–H positions through a radical pathway, giving meta-bromoaryl-substituted quinones without prior halogenation of the quinone substrate.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53429924495697,"sku":"NOR-89598969-1g","price":21.95,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53429924528465,"sku":"NOR-89598969-5g","price":39.95,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53429924561233,"sku":"NOR-89598969-10g","price":69.95,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53429924594001,"sku":"NOR-89598969-25g","price":109.95,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53429924626769,"sku":"NOR-89598969-50g","price":189.95,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53429924659537,"sku":"NOR-89598969-100g","price":329.95,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53429924692305,"sku":"NOR-89598969-250g","price":649.95,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53429924725073,"sku":"NOR-89598969-500g","price":1149.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Bromophenylboronic_Acid.png?v=1782683321"},{"product_id":"2-bromophenylboronic-acid-powder-cas-244205-40-1-purity-98","title":"2-Bromophenylboronic Acid | CAS 244205-40-1 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e244205-40-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e678-199-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01114672\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=CC=C1Br)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BBrO2\/c8-6-4-2-1-3-5(6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003ePLVCYMZAEQRYHJ-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2773294\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BBrO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e200.83 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e109-114 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2-Bromophenylboronic acid\u003c\/strong\u003e (2-bromobenzeneboronic acid, \u003cem\u003eo\u003c\/em\u003e-bromophenylboronic acid) carries the boronic acid and the aryl bromide \u003cem\u003eortho\u003c\/em\u003e to each other. This ortho relationship governs its Lewis acidity, substrate approach, chemoselectivity, and intramolecular\/sequential coupling behaviour.\u003c\/p\u003e\n\u003cp\u003eIt may contain small amounts of the cyclic anhydride 2-bromophenylboroxine; the two forms re-equilibrate under aqueous or basic coupling conditions, with minor effect on yield.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling at the boronic acid:\u003c\/strong\u003e Couples with aryl and heteroaryl electrophiles under matched Pd\/phosphine\/base conditions to install an \u003cem\u003eortho\u003c\/em\u003e-bromoaryl group. Where the Ar–Br is reserved for a later intramolecular step, choose catalyst and electrophile to avoid premature oxidative addition at that bond.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTandem Suzuki \/ intramolecular arylation to fused frameworks:\u003c\/strong\u003e The retained \u003cem\u003eortho\u003c\/em\u003e-Ar–Br serves intramolecular Pd-catalysed C–H or ring-closing arylation — giving fused-purine and phenanthridine systems (consecutive Suzuki then C–H arylation) and, by related tandem Suzuki\/C–H arylation, fluoranthene-type polycyclic aromatics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIterative cross-coupling with boron masking:\u003c\/strong\u003e Masking the boronic acid as its anthranilamide (AAM) boronate, which is inert under Suzuki conditions, allows coupling at the aryl bromide first; deprotection then reveals the boronic acid for the next step.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganocatalyst for direct amidation of carboxylic acids:\u003c\/strong\u003e A member of the Hall \u003cem\u003eortho\u003c\/em\u003e-halogenoarylboronic acid catalyst family for direct amide formation from carboxylic acids and amines. Under room-temperature dichloromethane \/ 4 Å molecular sieve conditions it is active but less effective than the \u003cem\u003eortho\u003c\/em\u003e-iodo and optimised MIBA catalysts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganocatalyst for Diels–Alder reactions of α,β-unsaturated and 2-alkynoic carboxylic acids:\u003c\/strong\u003e Catalyses via reversible boronic-acid activation of the carboxyl group. Reported for acrylic-acid Diels–Alder chemistry and the most efficient catalyst screened for [4+2] cycloadditions of 2-alkynoic acids, where activation lowers the dienophile LUMO through a mixed acyl boronate intermediate.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor further reading: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eBoron reagent selection for Suzuki–Miyaura coupling\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53436386115921,"sku":"NOR-244205401-1g","price":21.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53436386148689,"sku":"NOR-244205401-2g","price":32.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53436386181457,"sku":"NOR-244205401-5g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53436386214225,"sku":"NOR-244205401-10g","price":75.0,"currency_code":"EUR","in_stock":true},{"title":"25g","offer_id":53436386246993,"sku":"NOR-244205401-25g","price":140.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53436386279761,"sku":"NOR-244205401-50g","price":230.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53436386312529,"sku":"NOR-244205401-100g","price":375.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53436386345297,"sku":"NOR-244205401-250g","price":720.0,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53436386378065,"sku":"NOR-244205401-500g","price":1245.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_2-Bromophenylboronic_Acid.png?v=1782683321"},{"product_id":"4-hydroxymethylphenylboronic-acid-powder-cas-59016-93-2-purity-96","title":"4-(Hydroxymethyl)phenylboronic Acid | CAS 59016-93-2 | ≥96%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e59016-93-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e672-927-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00792672\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)CO)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H9BO3\/c9-5-6-1-3-7(4-2-6)8(10)11\/h1-4,9-11H,5H2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003ePZRPBPMLSSNFOM-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734706\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₉BO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e151.96 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e287-289 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥96%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-(Hydroxymethyl)phenylboronic Acid\u003c\/strong\u003e (4-Hydroxymethylbenzeneboronic Acid, 4-Boronobenzyl Alcohol) is a bifunctional arylboronic acid building block (combining arylboronic-acid and alcohol-derived reactivity).\u003c\/p\u003e\n\u003cp\u003eThe product may contain small amounts of the cyclic anhydride 4-(hydroxymethyl)phenylboroxine; under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, and alkenyl halides or triflates under standard Pd-catalysed aqueous-basic conditions to give biaryl, heterobiaryl, and styrene-type products; the para-benzylic alcohol is typically retained as a post-coupling functional handle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBifunctional handle for multistep synthesis (MIDA platform):\u003c\/strong\u003e this compound is a model substrate of the MIDA-boronate diversification platform. As its MIDA boronate, the benzylic hydroxyl is oxidised cleanly under Swern, PDC, TPAP\/NMO, Dess-Martin, and even Jones (H2SO4\/CrO3, high yield to the benzoic acid) while the C–B bond is preserved, giving direct access to 4-formyl- and 4-carboxy-phenyl MIDA boronates as iterative cross-coupling building blocks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydroxymethyl handle on the free boronic acid:\u003c\/strong\u003e standard benzylic alcohol chemistry applies — Appel halogenation, mesylation, tosylation, Mitsunobu, etherification, esterification, carbamate formation, controlled oxidation to the aldehyde or acid — within the compatibility limits of any onward steps in the target molecule (the unprotected boronic acid does not survive strongly oxidising conditions such as Jones).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible boronate ester formation with diols:\u003c\/strong\u003e as an arylboronic acid, forms reversible covalent boronate esters with cis-1,2- and 1,3-diols, saccharides, and catechols in aqueous media. The para-hydroxymethyl group provides an additional alcohol handle for scaffold or surface attachment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDynamic-covalent boronate–diol networks:\u003c\/strong\u003e class-level arylboronic-acid chemistry. The reversible boronate–diol bond underpins self-healing polymers, pH- and glucose-responsive hydrogels, and crosslinked dynamic networks; the bifunctional para-hydroxymethyl architecture provides an additional anchoring site for orthogonal modification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNLO-active polyurethane materials:\u003c\/strong\u003e building block in the synthesis of polyurethanes containing spindle-type chromophores for second-order nonlinear optical (NLO) applications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper-catalysed transformations of arylboronic acids in water:\u003c\/strong\u003e general Cu2O\/NH3-in-water method converting arylboronic acids into aryl iodides, azides, sulfones, phenols, anilines, and nitroarenes under air using inexpensive inorganic functional-group sources.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam-type C–N and C–O coupling:\u003c\/strong\u003e class-level arylboronic-acid chemistry. With Cu(OAc)2 or related Cu(II) systems and an amine, amide, sulfonamide, carbamate, phenol, or selected alcohol partner under mild aerobic conditions, gives the corresponding N-aryl or O-aryl product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e class-level arylboronic-acid chemistry. The boronic acid acts as the aryl donor in a three-component coupling with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde partner to give arylated amines, including α-aryl glycine and β-amino alcohol scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate derivatives:\u003c\/strong\u003e the corresponding pinacol ester (Bpin) and MIDA boronate are commercially documented. The MIDA derivative is a chromatographically tractable, air-stable boron surrogate compatible with iterative Suzuki coupling under slow-release conditions; the Bpin derivative is a commonly used protected boronate form for handling and cross-coupling workflows. Other boronate forms (neopentyl glycol, Bdan, trifluoroborate, MEA boronate) are class-level options to be selected case by case.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-classical arylation pathways:\u003c\/strong\u003e class-level arylboronic-acid chemistry. Arylboronic acids can participate in Suzuki–Miyaura-type coupling with arenediazonium salts under Pd catalysis, and in base-free Suzuki-type arylation with pentavalent triarylantimony diacetates, providing alternative access to biaryl products outside the usual aryl halide\/triflate electrophile set.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-halodeboronation:\u003c\/strong\u003e class-level arylboronic-acid chemistry. With NBS, NCS, or NIS, or related halogenating systems, the C–B bond can be converted to C–X to access the corresponding aryl halide; for this substrate, compatible conditions would lead to the 4-halobenzyl alcohol framework.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e class-level arylboronic-acid chemistry. With H2O2, oxone, sodium perborate, or copper-\/photo-mediated aerobic hydroxylation conditions, the C–B bond can be replaced by C–OH to give the corresponding phenol — here, 4-hydroxybenzyl alcohol.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53436536127825,"sku":"NOR-59016932-1g","price":21.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53436536160593,"sku":"NOR-59016932-2g","price":32.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53436536193361,"sku":"NOR-59016932-5g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53436536226129,"sku":"NOR-59016932-10g","price":75.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53436536258897,"sku":"NOR-59016932-25g","price":140.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53436536291665,"sku":"NOR-59016932-50g","price":230.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53436536324433,"sku":"NOR-59016932-100g","price":375.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53436536357201,"sku":"NOR-59016932-250g","price":720.0,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53436536389969,"sku":"NOR-59016932-500g","price":1245.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-_Hydroxymethyl_phenylboronic_Acid.png?v=1782683321"},{"product_id":"2-5-dibromophenylboronic-acid-powder-cas-1008106-93-1","title":"2,5-Dibromophenylboronic Acid | CAS 1008106-93-1 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1008106-93-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e999-188-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD09743927\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=C(C=CC(=C1)Br)Br)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H5BBr2O2\/c8-4-1-2-6(9)5(3-4)7(10)11\/h1-3,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eCMLBXUUGERIZOO-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e10039281\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₅BBr₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e279.72 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e237-241 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at 2–8°C under inert atmosphere. Keep container tightly sealed. Hygroscopic — protect from moisture and air\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2,5-Dibromophenylboronic Acid\u003c\/strong\u003e ((2,5-Dibromophenyl)boronic Acid, 2,5-Dibromobenzeneboronic Acid) is a trifunctional arylboronic acid building block with two positionally and electronically non-equivalent aryl bromide handles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e as an arylboronic acid, couples with suitably chosen aryl, heteroaryl, and alkenyl halides or triflates under Pd-catalysed basic conditions to give biaryl, heterobiaryl, and styrene-type products. Because the internal C2 and C5 aryl bromides are themselves potential Pd-oxidative-addition sites, chemoselective coupling at the boronate with retention of both Ar–Br handles is not the automatic outcome of generic Suzuki conditions: it requires deliberately designed conditions (catalyst\/ligand choice, base, controlled stoichiometry of the external electrophile, temperature) that favour transmetalation from the boronic acid over oxidative addition into the internal C–Br bonds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequential cross-coupling on a trifunctional scaffold:\u003c\/strong\u003e after the initial coupling at the boronic acid position under conditions that preserve the Ar–Br bonds, the two remaining C–Br bonds at C2 and C5 are available for sequential Pd-catalysed transformations (Suzuki, Stille, Negishi, Sonogashira, Heck, Buchwald–Hartwig amination, Miyaura borylation), enabling the construction of unsymmetrically trisubstituted phenylene cores from a single building block.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected-boronate lithiation \/ electrophile-trapping chemistry:\u003c\/strong\u003e the dibromoarylboron framework is related to protected dihalophenylboronate systems (e.g. dihalophenyl dioxazaborocines) used in low-temperature lithiation followed by electrophile trapping, a route to functionalised dihalophenylboronic acid derivatives when the boron centre is suitably protected. This chemistry is best described for suitably protected boronate systems; the unprotected B(OH)₂ form should not be assumed to tolerate organolithium conditions without a substrate-specific procedure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki polycondensation (SPC) monomer:\u003c\/strong\u003e with one boronic acid and two aryl bromides on the same ring, this is an AB₂ monomer. It self-condenses under Suzuki conditions without a comonomer, giving hyperbranched polyarylenes terminated in aryl bromide end groups. The two bromides are inequivalent — ortho (C2) and meta (C5) to boron — so the branching is irregular rather than symmetric. The bromo-terminated periphery is a handle for further functionalisation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam-type C–N and C–O coupling:\u003c\/strong\u003e class-level arylboronic-acid chemistry. With Cu(OAc)₂ or related Cu(II) systems and an amine, amide, sulfonamide, carbamate, phenol, or selected alcohol partner under mild aerobic conditions, gives the corresponding N-aryl or O-aryl product at the boronic acid carbon, with the two C–Br bonds normally retained.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e class-level arylboronic-acid chemistry. The boronic acid acts as the aryl donor in a three-component coupling with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde partner to give arylated amines, including α-aryl glycine and β-amino alcohol scaffolds carrying the 2,5-dibromophenyl group where the substrate is compatible.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53436746006865,"sku":"NOR-1008106931-1g","price":37.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53436746039633,"sku":"NOR-1008106931-2g","price":69.2,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53436746072401,"sku":"NOR-1008106931-5g","price":149.2,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53436746105169,"sku":"NOR-1008106931-10g","price":279.2,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53436746137937,"sku":"NOR-1008106931-25g","price":589.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_2-5-Dibromophenylboronic_Acid.png?v=1782683321"},{"product_id":"3-5-dibromophenylboronic-acid-powder-cas-117695-55-3-purity-98","title":"3,5-Dibromophenylboronic Acid | CAS 117695-55-3 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e117695-55-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e681-178-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01075725\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC(=C1)Br)Br)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H5BBr2O2\/c8-5-1-4(7(10)11)2-6(9)3-5\/h1-3,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eWQBLCGDZYFKINX-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734689\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₅BBr₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e279.72 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow solid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature in a tightly sealed container. Protect from moisture and light. May contain varying amounts of boroxine anhydride.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3,5-Dibromophenylboronic Acid\u003c\/strong\u003e is a trifunctional arylboronic acid building block with two electronically equivalent aryl bromide handles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChemoselective and sequential Suzuki–Miyaura coupling to C3-symmetric arenes:\u003c\/strong\u003e the C–B bond couples with aryl, heteroaryl, and alkenyl halides or triflates under Pd\/base to give biaryl, heterobiaryl, and styrene-type products. Coupling first at boron while keeping both Ar–Br bonds is not the automatic outcome of generic conditions, because the equivalent C3 and C5 bromides are themselves oxidative-addition sites; it requires designed conditions (catalyst\/ligand, base, electrophile stoichiometry, temperature) that favour transmetalation over oxidative addition into C–Br. With the bromides retained, they serve as handles for further Pd-catalysed coupling (Suzuki, Stille, Negishi, Sonogashira, Heck, Buchwald–Hartwig, Miyaura borylation); because the two are equivalent, the stoichiometry of the second electrophile — not site discrimination — sets mono- versus di-substitution, giving a 3-substituted-5-bromo or a symmetric 3,5-disubstituted arene. Three identical aryls at C1\/C3\/C5 give a C3-symmetric 1,3,5-triarylbenzene with 120° three-fold geometry — a core motif for star-shaped π-conjugated oligomers, tripodal ligands, discotic liquid crystals, and oligophenylene precursors to nanographenes and hexabenzocoronenes by Scholl cyclodehydrogenation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAB₂ Suzuki polycondensation to hyperbranched poly(m-phenylene)s:\u003c\/strong\u003e with no external partner, the single B(OH)₂ (\"A\") and two equivalent Ar–Br (\"B\") functions make it an AB₂ monomer that self-condenses under Pd catalysis to hyperbranched poly(m-phenylene)s with a bromide-terminated periphery. Related AB₂ monomers (e.g. m-terphenyl types under Pd(OAc)₂\/SPhos) reach higher molecular weight and lower dispersity via a pseudo-chain-growth, catalyst-transfer pathway.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtected-boronate lithiation \/ electrophile-trapping chemistry:\u003c\/strong\u003e the dibromoarylboron framework is related to protected dihalophenylboronate systems (e.g. dihalophenyl dioxazaborocines) used in low-temperature lithiation followed by electrophile trapping, a route to functionalised dihalophenylboronic acid derivatives when the boron centre is suitably protected. This chemistry is best described for suitably protected boronate systems; the unprotected B(OH)₂ form should not be assumed to tolerate organolithium conditions without a substrate-specific procedure.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam-type C–N and C–O coupling:\u003c\/strong\u003e class-level arylboronic-acid chemistry.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e class-level arylboronic-acid chemistry. The boronic acid acts as the aryl donor in a three-component coupling with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde partner to give arylated amines.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReversible boronate ester formation with diols:\u003c\/strong\u003e class-level arylboronic-acid chemistry. As an arylboronic acid, forms reversible covalent boronate esters with cis-1,2- and 1,3-diols, saccharides, and catechols in aqueous media. The two meta-Br substituents are electron-withdrawing by Hammett σₘ values and are expected to lower the boronic-acid pKa relative to the unsubstituted phenylboronic-acid baseline (~8.8), shifting the boronate\/boronic-acid equilibrium toward the boronate form at less basic pH.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53439736512849,"sku":"NOR-117695553-1g","price":25.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53439736545617,"sku":"NOR-117695553-2g","price":37.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53439736578385,"sku":"NOR-117695553-5g","price":57.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53439736611153,"sku":"NOR-117695553-10g","price":98.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53439736643921,"sku":"NOR-117695553-25g","price":189.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53439736676689,"sku":"NOR-117695553-50g","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53439736709457,"sku":"NOR-117695553-100g","price":549.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53439736742225,"sku":"NOR-117695553-250g","price":995.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-5-Dibromophenylboronic_Acid.png?v=1782683321"},{"product_id":"3-hydroxymethylphenylboronic-acid-cas-87199-15-3","title":"3-(Hydroxymethyl)phenylboronic Acid | CAS 87199-15-3 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e87199-15-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e672-931-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01317846\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC=C1)CO)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H9BO3\/c9-5-6-2-1-3-7(4-6)8(10)11\/h1-4,9-11H,5H2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eHGTDLKXUWVKLQX-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734662\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₉BO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e151.96 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e95-99 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-(Hydroxymethyl)phenylboronic Acid\u003c\/strong\u003e is a bifunctional arylboronic acid building block with a meta-substitution pattern placing the boronic-acid and benzylic alcohol handles at a 120° relative disposition.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e Couples with aryl, heteroaryl, and alkenyl halides or triflates under standard Pd-catalysed aqueous-basic conditions to give biaryl, heterobiaryl, and styrene-type products; the meta-benzylic alcohol is retained as a post-coupling functional handle.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHydroxymethyl handle on the free boronic acid:\u003c\/strong\u003e Standard benzylic alcohol chemistry applies — Appel halogenation, mesylation, tosylation, Mitsunobu, etherification, esterification, carbamate formation, controlled oxidation to the aldehyde or acid — within the compatibility limits of any onward steps in the target molecule.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReversible boronate ester formation with diols:\u003c\/strong\u003e Forms reversible covalent boronate esters with cis-1,2- and 1,3-diols, saccharides, and catechols in aqueous media. The meta-hydroxymethyl group provides an additional alcohol handle for scaffold attachment, surface attachment, or orthogonal modification.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDynamic-covalent boronate–diol networks:\u003c\/strong\u003e The reversible boronate–diol bond underpins self-healing polymers, pH- and glucose-responsive hydrogels, and crosslinked dynamic networks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper-catalysed transformations of arylboronic acids in water:\u003c\/strong\u003e The Cu2O\/ammonia-in-water system converts arylboronic acids to aryl iodides, azides, sulfones, phenols, anilines, and nitroarenes under air, with inorganic salt and ammonia as the functional-group sources.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper-mediated trifluoromethylation:\u003c\/strong\u003e Substrate in copper-mediated trifluoromethylation of arylboronic acids, giving the meta-trifluoromethylbenzyl alcohol framework under Cu\/CF3-source conditions outside the conventional Pd\/aryl-halide manifold.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam-type C–N and C–O coupling:\u003c\/strong\u003e With Cu(OAc)2 or related Cu(II) systems and an amine, amide, sulfonamide, carbamate, phenol, or selected alcohol partner under mild aerobic conditions, gives the corresponding N-aryl or O-aryl product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e The boronic acid acts as the aryl donor in a three-component coupling with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde partner to give arylated amines, including α-aryl glycine and β-amino alcohol scaffolds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtected boronate derivatives:\u003c\/strong\u003e The pinacol ester (Bpin, CAS 443776-76-9) is commercially documented. Other protected forms include the MIDA boronate, neopentyl glycol ester, Bdan, trifluoroborate, and MEA boronate. The MIDA boronate is a chromatographically tractable, air-stable boron surrogate compatible with iterative Suzuki coupling under slow-release conditions; the Bpin ester is a common protected form for handling and cross-coupling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNon-classical arylation pathways:\u003c\/strong\u003e Arylboronic acids participate in Suzuki–Miyaura-type coupling with arenediazonium salts under Pd catalysis and in base-free Suzuki-type arylation with pentavalent triarylantimony diacetates, giving biaryl products from electrophiles outside the usual aryl halide\/triflate set.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53472304169297,"sku":"NOR-87199153-5g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53472304202065,"sku":"NOR-87199153-10g","price":70.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53472304234833,"sku":"NOR-87199153-25g","price":152.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53472371769681,"sku":"NOR-87199153-50g","price":271.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53472304267601,"sku":"NOR-87199153-100g","price":474.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Hydroxymethyl_phenylboronic_Acid.png?v=1782697212"},{"product_id":"3-furanboronic-acid-cas-55552-70-0","title":"3-Furanboronic Acid | CAS 55552-70-0 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e55552-70-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e672-302-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01319007\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=COC=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C4H5BO3\/c6-5(7)4-1-2-8-3-4\/h1-3,6-7H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eCYEFKCRAAGLNHW-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734358\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₄H₅BO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e111.89 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e139-144 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 24 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore refrigerated (2–8 °C) in a tightly sealed container, protected from moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Furanboronic acid\u003c\/strong\u003e (furan-3-ylboronic acid, 3-furylboronic acid) is a five-membered heteroarylboronic acid where the relative positioning of boron center and ring oxygen prevents the α-carbanion stabilisation pathway operative for the 2-isomer which translates into slower aqueous protodeboronation and the absence of disproportionation cascade processes.\u003c\/p\u003e\n\u003cp\u003eThe product may contain small amounts of the cyclic anhydride furan-3-ylboroxine; under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl and N-heteroaryl halides (pyridines, pyrimidines, quinolines) using Pd or Ni catalysis. Compatible with activated\/unactivated chlorides and biodegradable aqueous solvent systems.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeteroaryl–heteroaryl coupling:\u003c\/strong\u003e couples with N-heteroaryl halides — including bromo- and chloropyridines, halopyrimidines, and bromoquinolines — under suitably chosen Pd or Ni conditions, supporting its use for constructing mixed five\/six-membered heterobiaryl motifs common in pharmaceutical and agrochemical intermediates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtodeboronation behaviour:\u003c\/strong\u003e furan-2-boronic acid undergoes high-concentration disproportionation near its pKa, sequentially forming difurylborinic acid and trifurylborane before protodeboronation. In 3-furanboronic acid, the β-positioned boron prevents the arrangement required for this cascade. Nevertheless, the compound remains condition-sensitive; pH, base, concentration, and temperature must still be carefully controlled to avoid protodeboronation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNi-catalysed Suzuki coupling:\u003c\/strong\u003e substrate for Suzuki–Miyaura coupling in green solvents to construct N-heteroaryl–furan biaryls (e.g., 5-(furan-3-yl)pyrimidine from 5-bromopyrimidine). Compatible with aryl\/heteroaryl halides and phenol-derived electrophiles (carbamates, sulfamates, pivalates).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiol recognition and enzyme immobilisation:\u003c\/strong\u003e forms reversible cyclic boronate esters with cis-1,2- and 1,3-diols and glycan motifs in aqueous solutions. Oxidative electropolymerisation of a uricase–furan-3-boronic acid adduct on a Pd-plated multiwalled-carbon-nanotube\/Au electrode yields a bionanocomposite functioning as an amperometric uric-acid biosensor and a uric-acid\/O₂ enzymatic biofuel cell bioanode.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam N-arylation:\u003c\/strong\u003e acts as the boron coupling partner in Cu(II)-mediated N-arylation of NH-heterocycles, anilines, and amides under mild aerobic conditions. Requires standard substrate-specific screening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich:\u003c\/strong\u003e participates in three-component coupling with amines and aldehydes (or glyoxylic \/ α-hydroxy aldehydes) to yield arylated amines, α-amino acid derivatives, or β-amino alcohols. Requires substrate-specific screening for optimal furan-3-yl transfer.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpso-substitution (halodeboronation and hydroxylation):\u003c\/strong\u003e the B(OH)₂ group undergoes oxidative replacement by halogens (Cl, Br, I) via N-haloimides, or by OH via peroxide oxidation, yielding 3-halo- or 3-hydroxyfurans. Careful screening is required, as the furan 2,5-positions are highly sensitive to electrophilic oxidation and halogenation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate esters:\u003c\/strong\u003e the pinacol ester (CAS 248924-59-6) offers a stable format for handling and cross-coupling. Other slow-release strategies — like MIDA boronates and potassium organotrifluoroborates — improve chromatographic handling, shelf stability, and iterative controlled-release Suzuki–Miyaura couplings (requires confirmed substrate-specific preparation protocols).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor comprehensive protocols on boronic acids, esters, protodeboronation, boroxine content, and reagent selection, refer to NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53473253785937,"sku":"NOR-55552700-1g","price":27.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53473253851473,"sku":"NOR-55552700-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53473253818705,"sku":"NOR-55552700-5g","price":85.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53473253884241,"sku":"NOR-55552700-10g","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53473253917009,"sku":"NOR-55552700-25g","price":275.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53473253949777,"sku":"NOR-55552700-50g","price":490.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53473293959505,"sku":"NOR-55552700-100g","price":895.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Furanboronic_Acid.png?v=1782683321"},{"product_id":"4-diphenylamino-phenylboronic-acid-cas-201802-67-7","title":"Triphenylamine-4-boronic Acid | CAS 201802-67-7 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e201802-67-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e627-214-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD06798117\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=CC=CC=C3)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C18H16BNO2\/c21-19(22)15-11-13-18(14-12-15)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17\/h1-14,21-22H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eTWWQCBRELPOMER-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e12166934\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₈H₁₆BNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e289.14 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e110-115 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in DMF, DMSO, insoluble in water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light green crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-(Diphenylamino)phenylboronic acid\u003c\/strong\u003e (triphenylamine-4-boronic acid, 4-DPBA) is an arylboronic acid that installs an electron-rich triphenylamine donor into extended π-conjugated architectures by Suzuki–Miyaura coupling. The triphenylamine moiety is a propeller-shaped donor used in hole-transporting and emissive organic electronic materials; its geometry reduces π-stacking and supports amorphous film formation.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-(diphenylamino)phenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl and heteroaryl halides under Pd catalysis to give biaryls bearing the triphenylamine donor. The electron-rich diphenylamino group builds extended π-conjugated systems including p-quaterphenyl, oligoarylene, and optoelectronic donor architectures.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnd-capping of oligofluorenes for blue OLED \/ PLED materials:\u003c\/strong\u003e Suzuki coupling at fluorene chain termini installs the diphenylamino group as a hole-transporting end-cap, lowering the first ionisation potential, enhancing thermal stability, and inducing amorphous morphological stability of blue-emitting fluorene oligomers.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePerylene dye functionalisation:\u003c\/strong\u003e Suzuki coupling of multi-brominated perylene monoimide cores gives tri- and tetra-(triphenylamine)-substituted perylene monoimides with broad absorption extending to ~750 nm. The corresponding perylene monoanhydrides serve as light-harvesting sensitisers in dye-sensitised solar cells, the tetra-substituted derivative giving the highest power conversion efficiency in that family.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSolid-state blue emitters with dimesitylboryl acceptors:\u003c\/strong\u003e Suzuki coupling installs the diphenylamino donor onto p-quaterphenyl frameworks bearing a bulky dimesitylboryl acceptor, giving twisted bipolar D–A architectures with intramolecular charge-transfer emission, large Stokes shift, suppressed π-stacking, high thermal stability, and bright blue fluorescence with high solid-state quantum yields.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMultiphoton blue photoluminescence and lasing:\u003c\/strong\u003e diphenylamino end-caps on ladder-type oligo(p-phenylene) scaffolds give strong multiphoton-excited (two- to five-photon) upconverted blue photoluminescence and efficient blue lasing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki polycondensation and end-capping for conjugated polymers:\u003c\/strong\u003e as a monofunctional building block or end-capper, it introduces triphenylamine units into conjugated polymer backbones, side chains, or termini. These p-type, hole-transporting polymers are investigated as active or transport layers in OLEDs, OFETs, and bulk-heterojunction organic photovoltaics.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtodeboronation and condition sensitivity:\u003c\/strong\u003e stability under aqueous-basic conditions depends on substituent, pH, base, concentration, and temperature. For electron-rich triarylamine substrates, conditions and exposure time are matched to the coupling partner; slow-release boron formats suit prolonged aqueous-basic exposure.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtected boronate ester forms:\u003c\/strong\u003e the pinacol (Bpin) ester is commercially available as an electron-rich protected form for handling and Suzuki–Miyaura coupling. MIDA boronates and potassium organotrifluoroborates are slow-release formats for chromatographic handling, shelf stability, or controlled-release coupling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53473917337937,"sku":"NOR-201802677-1g","price":22.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53473917370705,"sku":"NOR-201802677-2g","price":35.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53473917403473,"sku":"NOR-201802677-5g","price":64.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53473917436241,"sku":"NOR-201802677-10g","price":101.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53473917469009,"sku":"NOR-201802677-25g","price":189.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53473917501777,"sku":"NOR-201802677-50g","price":315.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53473917534545,"sku":"NOR-201802677-100g","price":504.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Triphenylamine-4-boronic_Acid.png?v=1782683321"},{"product_id":"4-trifluoromethoxyphenylboronic-acid-cas-139301-27-2","title":"4-Trifluoromethoxyphenylboronic Acid | CAS 139301-27-2 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e139301-27-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e642-479-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01074648\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)OC(F)(F)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H6BF3O3\/c9-7(10,11)14-6-3-1-5(2-4-6)8(12)13\/h1-4,12-13H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eHUOFUOCSQCYFPW-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734386\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₆BF₃O₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e205.93 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e123–127 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-(Trifluoromethoxy)phenylboronic acid\u003c\/strong\u003e (4-(trifluoromethoxy)benzeneboronic acid) is a fluorinated arylboronic acid bearing the trifluoromethoxy (OCF₃) group at the para position. OCF₃ is moderately electron-withdrawing and highly lipophilic, a useful 4-(trifluoromethoxy)phenyl substituent for medicinal-chemistry, agrochemical, and fluorinated-materials research.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-(trifluoromethoxy)phenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, and alkenyl halides or pseudohalides under Pd catalysis to install the 4-(trifluoromethoxy)phenyl fragment onto biaryl, heterobiaryl, and styrenyl scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoronate–water equilibrium and acidity:\u003c\/strong\u003e pKa 8.11 ± 0.04 (spectrophotometric) and 8.03 ± 0.07 (potentiometric), roughly 0.7 units below the parent phenylboronic acid (pKa ≈ 8.8) but less acidic than the 4-trifluoromethyl analogue (7.82 \/ 7.90). The narrower gap relative to CF₃ reflects partial oxygen lone-pair donation attenuating the inductive effect of OCF₃.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquid-crystal building block:\u003c\/strong\u003e Suzuki–Miyaura coupling via the 1,3,2-dioxaborinane or pinacol boronate ester installs the 4-(trifluoromethoxy)phenyl fragment into biphenyl, ethynyl-biphenyl, and ester-linked rod-like mesogenic cores. Infrared-oriented liquid-crystal studies on these intermediates evaluate mesomorphic behaviour, phase-transition temperatures, refractive indices, birefringence, and mid-wave infrared properties.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePerovskite solar-cell interface modifier:\u003c\/strong\u003e investigated as a fluorinated phenylboronic-acid modifier at the perovskite\/C₆₀ interface in inverted (CsFAMA)Pb(IBr)₃ cells, alongside its 4-trifluoromethyl analogue. Modifiers of this class passivate interfacial defects, suppress non-radiative recombination, enhance charge extraction, and reduce trap-state density; the 4-trifluoromethyl analogue showed stronger device performance than the 4-(trifluoromethoxy) analogue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e the boronic acid acts as the aryl donor in copper-mediated C–N, C–O, and C–S bond formation under aerobic conditions, transferring the 4-(trifluoromethoxy)phenyl group to amines, anilines, amides, phenols, alcohols, or thiols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e arylboronic acids act as aryl donors in three-component reactions with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde to give arylated amines, α-aryl glycine derivatives, or β-amino alcohol scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtodeboronation and condition sensitivity:\u003c\/strong\u003e stability under aqueous-basic conditions depends on substituent, pH, base, concentration, and temperature; pH-controlled speciation influences decomposition. Prolonged warm aqueous-basic exposure is managed by base, concentration, temperature, and time; slow-release boron formats suit extended coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate ester forms:\u003c\/strong\u003e the pinacol ester is commercially available as a protected form for handling and Suzuki–Miyaura coupling. MIDA boronates and potassium organotrifluoroborates improve shelf stability and enable controlled-release coupling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53474590392657,"sku":"NOR-139301272-1g","price":25.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53474602385745,"sku":"NOR-139301272-2g","price":39.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53474590425425,"sku":"NOR-139301272-5g","price":49.2,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53474590458193,"sku":"NOR-139301272-10g","price":74.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53474590490961,"sku":"NOR-139301272-25g","price":98.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53474590523729,"sku":"NOR-139301272-50g","price":129.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53474590556497,"sku":"NOR-139301272-100g","price":179.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53474590589265,"sku":"NOR-139301272-250g","price":329.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Trifluoromethoxyphenylboronic_Acid.png?v=1782683390"},{"product_id":"3-fluoro-4-morpholinophenylboronic-acid-cas-279262-09-8","title":"3-Fluoro-4-morpholinophenylboronic Acid | CAS 279262-09-8 | ≥95%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e279262-09-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD16883060\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=C(C=C1)N2CCOCC2)F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C10H13BFNO3\/c12-9-7-8(11(14)15)1-2-10(9)13-3-5-16-6-4-13\/h1-2,7,14-15H,3-6H2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eJCGKJBDGVMLWBG-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e53393407\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₀H₁₃BFNO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e225.03 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e141–145 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at 2–8°C under an inert atmosphere in a tightly sealed container. Protect from moisture and light. May contain varying amounts of boroxine anhydride\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Fluoro-4-morpholinophenylboronic acid\u003c\/strong\u003e (3-fluoro-4-morpholin-4-ylphenylboronic acid) combines a boronic-acid coupling handle, a para-morpholine ring, and a meta-fluorine in one building block. It is a privileged 3-fluoro-4-morpholinophenyl motif in medicinal-chemistry scaffold design.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 3-fluoro-4-morpholinophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, and alkenyl halides or pseudohalides under Pd catalysis to install the 3-fluoro-4-morpholinophenyl fragment onto biaryl, heterobiaryl, and styrenyl scaffolds. It couples with chloro-, bromo-, and iodo-substituted nitrogen heterocycles such as pyrimidines, pyridines, pyrazines, triazines, and pyridopyrimidines, giving morpholino-fluoroaryl heteroaromatic products in a convergent step.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMedicinal-chemistry scaffold synthesis:\u003c\/strong\u003e the 3-fluoro-4-morpholinophenyl fragment builds heteroaryl-linked arylmorpholine libraries by Suzuki–Miyaura coupling, including kinase-inhibitor scaffolds in the PI3K, AKT, and mTOR family. The morpholine oxygen serves as the hydrogen-bond acceptor toward the conserved hinge-region backbone amide of the ATP-binding pocket, the morpholine nitrogen tethering the ring to the aryl scaffold; the precise binding role depends on the coupled heteroaryl core, substitution pattern, and molecular context.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSubstituent positioning and electronic profile:\u003c\/strong\u003e the 4-morpholino substituent is an electron-donating arylamino group (π-donation via the nitrogen lone pair); the 3-fluoro substituent is inductively electron-withdrawing relative to the boronic acid (σm ≈ +0.34). The fragment contributes hydrogen-bond-acceptor character and solubility tuning through the morpholine oxygen, an aryl-F ¹⁹F NMR reporter for tracking the fragment, and a ring position for blocking or redirecting oxidative aromatic metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtodeboronation and condition sensitivity:\u003c\/strong\u003e stability under aqueous-basic conditions depends on substituent, pH, base, concentration, and temperature; electron-rich aminated arylboronic acids are not assumed to tolerate prolonged warm aqueous-basic exposure without optimisation. For this compound, mild bases, controlled aqueous content, moderate temperatures, and limited reaction times are sensible Suzuki starting points; slow-release boron formats suit extended coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e the boronic acid acts as the aryl donor in copper-mediated C–N, C–O, and C–S bond formation under aerobic conditions, transferring the 3-fluoro-4-morpholinophenyl group to amines, anilines, amides, phenols, alcohols, or thiols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e arylboronic acids act as aryl donors in three-component reactions with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde to give arylated amines, α-aryl glycine derivatives, or β-amino alcohol scaffolds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtected boronate ester forms:\u003c\/strong\u003e the pinacol ester is commercially available as a protected form for handling and Suzuki–Miyaura coupling. MIDA boronates and potassium organotrifluoroborates improve shelf stability and enable controlled-release coupling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53475630350673,"sku":"NOR-279262098-1g","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53475630383441,"sku":"NOR-279262098-2g","price":295.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53475630416209,"sku":"NOR-279262098-5g","price":589.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Fluoro-4-morpholinophenylboronic_Acid.png?v=1782683390"},{"product_id":"3-4-dichlorophenylboronic-acid-powder-cas-151169-75-4-purity-98","title":"3,4-Dichlorophenylboronic Acid | CAS 151169-75-4 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e151169-75-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e629-198-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01074646\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=C(C=C1)Cl)Cl)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H5BCl2O2\/c8-5-2-1-4(7(10)11)3-6(5)9\/h1-3,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eJKIGHOARKAIPJI-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734330\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₅BCl₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e190.82 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e280-285 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature in a tightly sealed container. Protect from moisture and light. May contain varying amounts of boroxine anhydride\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3,4-Dichlorophenylboronic acid\u003c\/strong\u003e ((3,4-dichlorophenyl)boronic acid) is a moderately-to-strongly electron-withdrawing, trifunctional arylboronic acid building block.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 3,4-dichlorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura coupling and sequential C–Cl functionalisation:\u003c\/strong\u003e couples with aryl, heteroaryl, and alkenyl halides or pseudohalides under Pd catalysis to install the 3,4-dichlorophenyl fragment onto biaryl, heterobiaryl, and styrenyl scaffolds. The C–B bond couples selectively while the two ring C–Cl bonds are retained, giving 3,4-dichlorobiaryl and -biheteroaryl scaffolds. The retained C–Cl handles are addressed later under aryl-chloride activation conditions — Buchwald–Hartwig amination, further Suzuki coupling, or Pd\/phosphine catalysis (Pd\/SPhos, XPhos, BrettPhos, cataCXium A, Pd(\u003cem\u003et\u003c\/em\u003e-Bu)₃P); nucleophilic aromatic substitution applies only where the aryl chloride is sufficiently activated (electron-withdrawing groups, electron-deficient heteroaryl context).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePolychlorinated biphenyl (PCB) congener synthesis:\u003c\/strong\u003e Suzuki-based routes give defined PCB congeners and metabolites used as authentic reference materials in environmental chemistry, toxicology, and metabolism research. Modified Suzuki coupling of chlorinated arylboronic acids with bromochlorobenzenes gives selected PCB substitution patterns in moderate to good yields, avoiding separation from technical PCB mixtures.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal-chemistry and agrochemical scaffold synthesis:\u003c\/strong\u003e the 3,4-dichlorophenyl fragment is a lipophilic aryl substituent in medicinal-chemistry and agrochemical building-block research. It is used in heteroaryl and biaryl scaffold construction, including \u003cem\u003eMycobacterium tuberculosis\u003c\/em\u003e H37Rv chorismate mutase inhibitor scaffolds. In agrochemical building blocks, dichloroaryl substitution tunes lipophilicity, electronic character, and metabolic stability. The role of the 3,4-dichlorophenyl group depends on the complete molecular scaffold, substitution pattern, and coupling partner.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSubstituent positioning and electronic profile:\u003c\/strong\u003e the 3-Cl substituent acts through the meta-inductive pathway with no resonance compensation (σm ≈ +0.37); the 4-Cl substituent is net electron-withdrawing, partially moderated by weak π-donation from chlorine (σp ≈ +0.23 net). The combined pattern gives an electron-deficient arylboronic acid with a predicted lower pKa than phenylboronic acid, shifting boronic-acid\/boronate speciation toward the boronate under aqueous-basic conditions. The natural-abundance ³⁵Cl\/³⁷Cl isotope pattern provides a distinctive mass-spectrometry handle for tracking the fragment through coupling, work-up, and purification.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtodeboronation and condition sensitivity:\u003c\/strong\u003e stability under aqueous-basic conditions depends on substituent, pH, base, concentration, and temperature; conditions are selected for the specific electrophile, base, solvent, and exposure time. This compound also appears in lithiation\/borylation–protodeboronation methodology involving homoallyl carbamates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam coupling:\u003c\/strong\u003e the boronic acid acts as the aryl donor in copper-mediated C–N, C–O, and C–S bond formation under aerobic conditions, transferring the 3,4-dichlorophenyl group to amines, anilines, amides, phenols, alcohols, or thiols.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePetasis borono-Mannich reaction:\u003c\/strong\u003e arylboronic acids act as aryl donors in three-component reactions with an amine and an aldehyde, glyoxylic acid, or α-hydroxy aldehyde to give arylated amines, α-aryl glycine derivatives, or β-amino alcohol scaffolds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtected boronate ester forms:\u003c\/strong\u003e the pinacol ester (2-(3,4-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, CAS 401797-02-2, MW 272.97) is commercially available as a protected form for handling and Suzuki–Miyaura coupling where the free boronic acid is inconvenient (chromatography, prolonged storage). MIDA boronates and potassium organotrifluoroborates enable controlled-release coupling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53501986308433,"sku":"NOR-151169754-1g","price":23.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53501986341201,"sku":"NOR-151169754-2g","price":31.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53501986373969,"sku":"NOR-151169754-5g","price":43.9,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53501986406737,"sku":"NOR-151169754-10g","price":67.9,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53501986439505,"sku":"NOR-151169754-25g","price":109.2,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53501986472273,"sku":"NOR-151169754-50g","price":189.2,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53501986505041,"sku":"NOR-151169754-100g","price":329.2,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53501986537809,"sku":"NOR-151169754-250g","price":589.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-4-Dichlorophenylboronic_Acid.png?v=1782683390"},{"product_id":"4-biphenylboronic-acid-cas-5122-94-1","title":"4-Biphenylboronic Acid | CAS 5122-94-1 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e5122-94-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e675-084-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00093311\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)C2=CC=CC=C2)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C12H11BO2\/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10\/h1-9,14-15H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eXPEIJWZLPWNNOK-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e151253\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₂H₁₁BO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e198.03 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e232-245 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature. Protect from moisture. May contain varying amounts of boroxine anhydride\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Biphenylboronic Acid\u003c\/strong\u003e ([1,1′-biphenyl]-4-ylboronic acid) is a π-extended arylboronic acid for installing a rigid 4-biphenyl unit.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-biphenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, or alkenyl electrophiles to give p-terphenyl, heteroaryl-biphenyl, styrenyl-biphenyl, and higher oligoaryl products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLiquid-crystal intermediates:\u003c\/strong\u003e provides a rigid linear biphenyl fragment for terphenyl-type mesogenic cores and rod-shaped aromatic materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConjugated materials building block:\u003c\/strong\u003e introduces biphenyl segments into π-conjugated oligomers, chromophores, and organic semiconductor intermediates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThiophene–phenylene hybrid scaffolds:\u003c\/strong\u003e with aryl-halide partners gives thienyl-substituted terphenyl and quinquephenyl frameworks for extended heteroaryl–phenylene systems.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLuminol–peroxidase chemiluminescence enhancement:\u003c\/strong\u003e acts as an enhancer in luminol–hydrogen peroxide–horseradish peroxidase systems, including capillary-electrophoresis chemiluminescence detection.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoronate–diol recognition:\u003c\/strong\u003e forms reversible boronate complexes with the diol groups of mono- and disaccharides, used to estimate apparent stability constants in capillary-electrophoresis molecular-recognition studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":53502281548113,"sku":"NOR-5122941-5g","price":23.9,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53502281580881,"sku":"NOR-5122941-10g","price":34.9,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53502281613649,"sku":"NOR-5122941-25g","price":54.9,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53502281646417,"sku":"NOR-5122941-50g","price":89.9,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53502281679185,"sku":"NOR-5122941-100g","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53502281711953,"sku":"NOR-5122941-250g","price":329.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Biphenylboronic_Acid.png?v=1782683391"},{"product_id":"5-pyrimidylboronic-acid-powder-cas-109299-78-7-purity-98","title":"5-Pyrimidylboronic Acid | CAS 109299-78-7 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e109299-78-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e673-929-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD03002366\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CN=CN=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C4H5BN2O2\/c8-5(9)4-1-6-3-7-2-4\/h1-3,8-9H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eHZFPPBMKGYINDF-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2795193\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₄H₅BN₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e123.91 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e110–114 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at 2–8°C in a tightly sealed container. Protect from moisture and light.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e5-Pyrimidylboronic Acid\u003c\/strong\u003e (pyrimidin-5-ylboronic acid) is a compact N-rich heteroarylboronic acid for installing the pyrimidin-5-yl unit into biaryl and heteroaryl frameworks.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 5-pyrimidylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, or alkenyl electrophiles to give pyrimidin-5-yl biaryls, heterobiaryls, and styrenyl heteroarenes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHeteroaryl–heteroaryl construction:\u003c\/strong\u003e documented in the synthesis of heteroarylpyrimidines by coupling with heteroaryl halide partners.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtodeboronation-sensitive coupling partner:\u003c\/strong\u003e N-heteroarylboronic acids can show condition-dependent protodeboronation; masked boronate forms or milder coupling conditions may improve reliability where instability is observed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePyrimidin-5-yl scaffold installation:\u003c\/strong\u003e introduces a diazine ring with two ring nitrogens, useful when replacing phenyl or pyridyl units in structure–property studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical and agrochemical intermediate:\u003c\/strong\u003e provides direct access to N-rich heteroaryl fragments for medicinal-chemistry and agrochemical intermediate libraries.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtected boronate derivatives:\u003c\/strong\u003e precursor to pinacol, neopentyl glycol, and other boronate forms where improved handling or staged cross-coupling is preferred.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53513917792593,"sku":"NOR-109299787-1g","price":29.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53513917825361,"sku":"NOR-109299787-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53513917858129,"sku":"NOR-109299787-5g","price":69.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53513917890897,"sku":"NOR-109299787-10g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53513917923665,"sku":"NOR-109299787-25g","price":235.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53513917956433,"sku":"NOR-109299787-50g","price":443.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53513917989201,"sku":"NOR-109299787-100g","price":831.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_5-Pyrimidylboronic_Acid.png?v=1782683391"},{"product_id":"4-boc-aminophenylboronic-acid-powder-cas-380430-49-9-purity-98","title":"(4-Boc-aminophenyl)boronic Acid | CAS 380430-49-9 | ≥98.0%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e380430-49-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e670-415-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD02093054\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)NC(=O)OC(C)(C)C)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C11H16BNO4\/c1-11(2,3)17-10(14)13-9-6-4-8(5-7-9)12(15)16\/h4-7,15-16H,1-3H3,(H,13,14)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eUBVOLHQIEQVXGM-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e3613184\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₁H₁₆BNO₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e237.06 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e199-204 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light orange powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore refrigerated (2–8 °C) in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e(4-Boc-aminophenyl)boronic Acid\u003c\/strong\u003e is a Boc-protected aminophenylboronic acid for introducing a masked 4-aminophenyl unit into coupled aryl frameworks.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-Boc-aminophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, or alkenyl electrophiles to give Boc-protected 4-aminobiaryl and related heteroaryl products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrthogonal protected-aniline handle:\u003c\/strong\u003e the boronic acid reacts at C–B while the Boc-protected amine is retained through many neutral or basic coupling conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e4-Aminobiaryl precursor:\u003c\/strong\u003e acid-mediated Boc removal after coupling reveals the corresponding aniline for downstream functionalisation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAmide, sulfonamide, and urea diversification:\u003c\/strong\u003e the deprotected aniline provides a practical handle for late-stage derivatisation of coupled biaryl intermediates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRhodium-catalysed allylic substitution:\u003c\/strong\u003e documented as an arylboronic-acid partner in desymmetrisation of meso-cyclic allylic dicarbonates via SN2′-type C–C bond formation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtected boronate derivatives:\u003c\/strong\u003e precursor to pinacol, neopentyl glycol, and related boronate forms where improved handling or staged coupling is preferred.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53514885202257,"sku":"NOR-380430499-1g","price":28.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53514885235025,"sku":"NOR-380430499-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53514885267793,"sku":"NOR-380430499-5g","price":69.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53514885300561,"sku":"NOR-380430499-10g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53514885333329,"sku":"NOR-380430499-25g","price":175.6,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53514885366097,"sku":"NOR-380430499-50g","price":299.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53514885398865,"sku":"NOR-380430499-100g","price":549.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53514892607825,"sku":"NOR-380430499-250g","price":1249.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Boc-aminophenyl_boronic_Acid.png?v=1782683391"},{"product_id":"3-thienylboronic-acid-cas-6165-69-1","title":"3-Thienylboronic Acid | CAS 6165-69-1 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e6165-69-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e629-166-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00151851\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CSC=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C4H5BO2S\/c6-5(7)4-1-2-8-3-4\/h1-3,6-7H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eQNMBSXGYAQZCTN-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e581760\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₄H₅BO₂S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e127.96 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e164–169 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at 2–8°C in a tightly sealed container. Protect from moisture and light. May contain varying amounts of boroxine anhydride\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Thienylboronic Acid\u003c\/strong\u003e (thiophene-3-boronic acid) is a sulfur-containing heteroarylboronic acid for installing the thiophen-3-yl unit into aromatic, heteroaromatic, and π-conjugated frameworks.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 3-thienylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, or alkenyl electrophiles to give thiophen-3-yl biaryls, heterobiaryls, styrenyl thiophenes, and extended heteroaryl products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHeteroaryl pharmaceutical intermediates:\u003c\/strong\u003e introduces a thiophene fragment into heteroaryl scaffolds used in medicinal-chemistry and agrochemical intermediate synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePorphyrin functionalisation:\u003c\/strong\u003e documented as a Suzuki partner for thienyl-substituted porphyrin synthesis, where the thiophene unit modifies the electronic structure of the macrocyclic chromophore.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImidazole scaffold construction:\u003c\/strong\u003e used to prepare thiophen-3-yl-substituted imidazole derivatives by cross-coupling, giving access to N\/S-heteroaryl frameworks for research libraries.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConductive polymer precursor:\u003c\/strong\u003e electropolymerises to poly(3-thienylboronic acid), combining a polythiophene-type backbone with pendant boronic acid groups.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoronate–diol recognition:\u003c\/strong\u003e the boronic acid group enables reversible interaction with saccharides and other diol-containing molecules in chemosensitive polymer and electrode systems.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53515459264849,"sku":"NOR-6165691-1g","price":22.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53515459297617,"sku":"NOR-6165691-5g","price":32.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53515459330385,"sku":"NOR-6165691-10g","price":47.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53515459363153,"sku":"NOR-6165691-25g","price":79.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53515459395921,"sku":"NOR-6165691-50g","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53515459428689,"sku":"NOR-6165691-100g","price":249.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53515459461457,"sku":"NOR-6165691-250g","price":549.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Thienylboronic_Acid.png?v=1782683391"},{"product_id":"potassium-5-bromothiophen-2-yl-trifluoroborate-powder-cas-1239370-98-9","title":"Potassium (5-Bromothiophen-2-yl)trifluoroborate | CAS 1239370-98-9 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1239370-98-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e806-714-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD17015269\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003e[B-](C1=CC=C(S1)Br)(F)(F)F.[K+]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C4H2BBrF3S.K\/c6-4-2-1-3(10-4)5(7,8)9;\/h1-2H;\/q-1;+1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eLNJIZRITMDDEGQ-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e49834929\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₄H₂BBrF₃KS\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e268.93 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water, methanol, acetone, acetonitrile, DMF. Poorly soluble in nonpolar organic solvents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore under inert atmosphere at 2–8°C in a tightly sealed container. Protect from moisture and light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePotassium (5-Bromothiophen-2-yl)trifluoroborate\u003c\/strong\u003e is a bifunctional heteroaryltrifluoroborate salt combining a thiophen-2-yltrifluoroborate coupling handle with a retained 5-bromo substituent.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e the trifluoroborate group couples with aryl, heteroaryl, or alkenyl electrophiles under Pd-catalysed aqueous-base conditions to install a 5-bromothiophen-2-yl unit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBifunctional C–B\/C–Br handle:\u003c\/strong\u003e the C–BF3K and C–Br sites can be addressed sequentially under matched cross-coupling conditions to access unsymmetrical 2,5-disubstituted thiophenes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSecond-site diversification:\u003c\/strong\u003e after initial Suzuki coupling, the retained bromide can support further C–C, C–N, or carbonylative transformations at the thiophene C5 position.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConjugated materials intermediate:\u003c\/strong\u003e provides a prefunctionalised thiophene unit for π-conjugated oligomers, donor–acceptor scaffolds, chromophores, and organic semiconductor intermediates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePolymer-building-block use:\u003c\/strong\u003e bifunctional thiophene monomers of this type are suited to stepwise or polycondensation approaches where regiochemical placement of thiophene units matters.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical and agrochemical scaffolds:\u003c\/strong\u003e enables modular synthesis of 2,5-disubstituted thiophene intermediates for medicinal-chemistry and agrochemical research libraries.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, organotrifluoroborates, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"500 mg","offer_id":53504478740817,"sku":"NOR-1239370989-500mg","price":69.0,"currency_code":"EUR","in_stock":true},{"title":"1.0 g","offer_id":53504478773585,"sku":"NOR-1239370989-1g","price":129.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53504478806353,"sku":"NOR-1239370989-2g","price":229.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53504478839121,"sku":"NOR-1239370989-5g","price":449.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Potassium_5-Bromothiophen-2-yl_trifluoroborate.png?v=1782683391"},{"product_id":"5-bromothiophen-2-yl-boronic-acid-cas-162607-17-2","title":"(5-Bromothiophen-2-yl)boronic Acid | CAS 162607-17-2 | ≥96%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e162607-17-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e678-207-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD02094028\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(S1)Br)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C4H4BBrO2S\/c6-4-2-1-3(9-4)5(7)8\/h1-2,7-8H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eUSJPOBDLWVCPGG-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734319\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₄H₄BBrO₂S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e206.85 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e95–100 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥96%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at –20°C in a tightly sealed container. Protect from moisture and light. May contain varying amounts of boroxine anhydride\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e(5-Bromothiophen-2-yl)boronic Acid\u003c\/strong\u003e is a bifunctional heteroarylboronic acid combining a thiophen-2-ylboronic acid coupling handle with a retained 5-bromo substituent.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 5-bromothiophen-2-ylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, or alkenyl electrophiles to install a 5-bromothiophen-2-yl unit in biaryl, heterobiaryl, and π-extended products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBifunctional C–B\/C–Br handle:\u003c\/strong\u003e the boronic acid and aryl bromide can be addressed sequentially under matched conditions to access unsymmetrical 2,5-disubstituted thiophenes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSecond-site diversification:\u003c\/strong\u003e after initial Suzuki coupling, the retained C5 bromide can support further Suzuki, Sonogashira, Buchwald–Hartwig, or carbonylative transformations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRatanhine intermediate:\u003c\/strong\u003e documented Suzuki–Miyaura coupling partner in the synthesis of ratanhine-type acetylenic thiophene natural-product frameworks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrganic sensitizer and BODIPY hybrids:\u003c\/strong\u003e used in Suzuki coupling routes to benzotriazole-containing dye-sensitised solar-cell sensitizers and meso-polyarylamide–BODIPY hybrid materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthynylarylboronate synthesis:\u003c\/strong\u003e the C5 bromide participates in microwave-assisted Sonogashira chemistry to give ethynyl-substituted arylboronate intermediates for further coupling or conjugation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, organotrifluoroborates, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 1–2 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 1–2 business days, duties and taxes prepaid\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53516364251473,"sku":"NOR-162607172-1g","price":30.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53516364284241,"sku":"NOR-162607172-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53516364317009,"sku":"NOR-162607172-5g","price":69.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53516364349777,"sku":"NOR-162607172-10g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53516364382545,"sku":"NOR-162607172-25g","price":175.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53516364415313,"sku":"NOR-162607172-50g","price":299.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53516364448081,"sku":"NOR-162607172-100g","price":599.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_5-Bromothiophen-2-yl_boronic_Acid.png?v=1782683391"},{"product_id":"pyrazole-3-boronic-acid-hydrate-cas-1310383-92-6","title":"Pyrazole-3-boronic Acid Hydrate | CAS 1310383-92-6 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1310383-92-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD11044442\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=NN1)(O)O.O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C3H5BN2O2.H2O\/c7-4(8)3-1-2-5-6-3;\/h1-2,7-8H,(H,5,6);1H2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eNXQCQMBEFQLICU-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e46739739\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₃H₇BN₂O₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e129.91 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white or light brown crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore under inert atmosphere at –20°C in a tightly sealed container, in a dark place. Protect from moisture and light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePyrazole-3-boronic Acid Hydrate\u003c\/strong\u003e (1H-pyrazol-3-ylboronic acid hydrate) is an unprotected N-heteroarylboronic acid for installing the pyrazol-3-yl unit into coupled aryl and heteroaryl frameworks.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride pyrazol-3-ylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e used to prepare 3-arylpyrazole and heteroaryl-pyrazole products; because the unprotected N-heteroarylboronic acid is prone to protodeboronation, condition screening is required.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtodeboronation-sensitive substrate:\u003c\/strong\u003e pyrazolylboronic acids are prone to C–B loss under mismatched conditions; protected boron forms or milder coupling conditions may improve reliability.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUnprotected pyrazole handle:\u003c\/strong\u003e the NH-bearing ring is retained in the coupled product, giving direct access to pyrazoles available for later N-functionalisation or salt formation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-heteroaryl scaffold installation:\u003c\/strong\u003e introduces a compact diazole unit with adjacent donor\/acceptor nitrogens for structure–property and fragment-extension studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal-chemistry intermediates:\u003c\/strong\u003e provides pyrazolyl fragments for heteroaryl libraries, kinase-research scaffolds, and other pharmaceutical-intermediate series.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAgrochemical intermediate synthesis:\u003c\/strong\u003e supports preparation of arylated pyrazole intermediates for crop-science and heterocycle research programmes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, organotrifluoroborates, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 1–2 business days.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 1–2 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"500 mg","offer_id":53516643008849,"sku":"NOR-1310383926-500mg","price":45.9,"currency_code":"EUR","in_stock":true},{"title":"1.0 g","offer_id":53516643041617,"sku":"NOR-1310383926-1g","price":73.2,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53516643074385,"sku":"NOR-1310383926-2g","price":129.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53516643107153,"sku":"NOR-1310383926-5g","price":279.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Pyrazole-3-boronic_Acid_Hydrate.png?v=1782683391"},{"product_id":"potassium-cyclopropyltrifluoroborate-cas-1065010-87-8","title":"Potassium Cyclopropyltrifluoroborate | CAS 1065010-87-8 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1065010-87-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e678-462-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD09265031\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003e[B-](C1CC1)(F)(F)F.[K+]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C3H5BF3.K\/c5-4(6,7)3-1-2-3;\/h3H,1-2H2;\/q-1;+1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eCFMLURFHOSOXRC-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e23697338\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₃H₅BF₃K\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e147.98 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e348–350 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water, methanol, acetone, acetonitrile, DMSO and DMF; poorly soluble in diethyl ether, hexane, toluene and dichloromethane.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePotassium Cyclopropyltrifluoroborate\u003c\/strong\u003e is a bench-stable salt that transfers a cyclopropyl group in cross-coupling and radical C–C bond-forming reactions. As a masked boronic acid, it hydrolyses slowly in protic media to release the active nucleophile in situ.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura coupling:\u003c\/strong\u003e couples with aryl and heteroaryl chlorides, bromides, and mesylated phenols to give arylcyclopropanes, a useful motif in medicinal-chemistry, agrochemical, and fragment-library synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCsp³–Csp³ alkyl–alkyl coupling:\u003c\/strong\u003e couples with benzyl chlorides to give benzylcyclopropanes, a harder transformation than coupling with aryl electrophiles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMinisci-type C–H alkylation:\u003c\/strong\u003e under photoredox conditions the cyclopropyl radical adds to electron-deficient N-heteroarenes, installing the group by direct C–H functionalisation without prior halogenation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam cyclopropylation:\u003c\/strong\u003e transfers the cyclopropyl group to phenols and selected azaheterocycles under Cu-mediated oxidative coupling to access cyclopropyl ethers and N-cyclopropyl heterocycles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, organotrifluoroborates, protodeboronation, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53476215685457,"sku":"NOR-1065010878-1g","price":29.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53476215718225,"sku":"NOR-1065010878-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53476215750993,"sku":"NOR-1065010878-5g","price":79.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53476215783761,"sku":"NOR-1065010878-10g","price":129.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53476215816529,"sku":"NOR-1065010878-25g","price":275.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53476215849297,"sku":"NOR-1065010878-50g","price":449.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53476215882065,"sku":"NOR-1065010878-100g","price":669.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Potassium_Cyclopropyltrifluoroborate.png?v=1782683391"},{"product_id":"1h-indol-5-yl-boronic-acid-cas-144104-59-6","title":"(1H-Indol-5-yl)boronic Acid | CAS 144104-59-6 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e144104-59-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e627-180-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01319013\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC2=C(C=C1)NC=C2)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C8H8BNO2\/c11-9(12)7-1-2-8-6(5-7)3-4-10-8\/h1-5,10-12H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eVHADYSUJZAPXOW-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734361\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₈H₈BNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e160.97 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e170–175 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light brown powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore refrigerated (2–8 °C) in a tightly sealed container, protected from light.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e(1H-Indol-5-yl)boronic Acid\u003c\/strong\u003e is an unprotected indolylboronic acid for installing the 1H-indol-5-yl unit into aryl, heteroaryl, polycyclic, and conjugated frameworks.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 1H-indol-5-ylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e couples with aryl, heteroaryl, and activated aryl electrophiles to give 5-arylindoles, heteroaryl-indoles, and π-extended indole products under matched Pd\/base conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePolycyclic scaffold synthesis:\u003c\/strong\u003e documented in Suzuki routes to aryl-hetarylfurocoumarins, aryl-substituted oxabenzindoles, and methanobenzindole frameworks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal-chemistry intermediates:\u003c\/strong\u003e provides indole-containing fragments for MMP-inhibitor intermediates, substituted pyrimidines, tubulin-polymerisation-inhibitor intermediates, and related pharmaceutical research scaffolds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRhodium-catalysed conjugate addition:\u003c\/strong\u003e serves as a heteroaryl donor in 1,4-addition to unprotected maleimides, giving indolyl-substituted succinimide products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOxidative coupling and trifluoromethylation:\u003c\/strong\u003e participates in Pd- or Cu-mediated coupling with mercaptoacetylenes to access sulfur-containing alkynyl indole derivatives; the boronic acid or related boronate forms can also access 5-trifluoromethylindoles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMaterials and organic electronics:\u003c\/strong\u003e indole-containing building blocks are used in organic electronic materials, including hole-transport and emissive-layer architectures. 5-Functionalised indole derivatives can be incorporated into conjugated oligomers and copolymers to tune bandgap, HOMO\/LUMO levels, and photophysical behaviour for photovoltaic, OLED, and fluorescence-sensor research.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, organotrifluoroborates, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53519083766097,"sku":"NOR-144104596-1g","price":32.2,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53519083798865,"sku":"NOR-144104596-2g","price":57.05,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53519083831633,"sku":"NOR-144104596-5g","price":124.2,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53519083864401,"sku":"NOR-144104596-10g","price":211.6,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53519083897169,"sku":"NOR-144104596-25g","price":437.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53519083929937,"sku":"NOR-144104596-50g","price":736.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53519083962705,"sku":"NOR-144104596-100g","price":1380.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_1H-Indol-5-yl_boronic_Acid.png?v=1782700533"},{"product_id":"1-methyl-1h-pyrazole-4-boronic-acid-cas-847818-55-7","title":"1-Methyl-1H-pyrazole-4-boronic Acid | CAS 847818-55-7 | ≥95%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e847818-55-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e690-821-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD09414709\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CN(N=C1)C)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C4H7BN2O2\/c1-7-3-4(2-6-7)5(8)9\/h2-3,8-9H,1H3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eRYGOBSYXIIUFOR-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e11263501\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₄H₇BN₂O₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e125.92 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore refrigerated (2–8 °C) in a tightly sealed container.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e1-Methyl-1H-pyrazole-4-boronic Acid\u003c\/strong\u003e ((1-methyl-1H-pyrazol-4-yl)boronic acid) is an N-methylated pyrazol-4-yl boronic acid building block.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 1-methyl-1H-pyrazol-4-ylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e installs the 1-methylpyrazol-4-yl group onto aryl, heteroaryl, and vinyl electrophiles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtodeboronation profile:\u003c\/strong\u003e boron at C4 (not adjacent to a ring nitrogen) makes it markedly more robust than 2-pyridyl, 5-thiazolyl, or 5-pyrazolyl boronic acids, which protodeboronate within seconds — not inert, though: a pH-dependent rate means couple under matched conditions and store cold.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-methyl medicinal-chemistry handle:\u003c\/strong\u003e N-methylation locks the tautomer, caps the donor N–H, and — via the electron-donating methyl — tunes the ring's basicity and electron density; the defined, weakly basic pyridine-type N2 serves as an H-bond acceptor for molecular recognition and ADME tuning.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLithium hydroxy ate complex:\u003c\/strong\u003e an isolable, bench-stable form that couples directly in Suzuki reactions without added base.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical and agrochemical building block:\u003c\/strong\u003e the pyrazole ring is prominent in both fields; this reagent installs the 1-methylpyrazol-4-yl unit for analogue series.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53519811641681,"sku":"NOR-847818557-1g","price":29.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53519811674449,"sku":"NOR-847818557-2g","price":49.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53519811707217,"sku":"NOR-847818557-5g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53519811739985,"sku":"NOR-847818557-10g","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53519811772753,"sku":"NOR-847818557-25g","price":349.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53519811805521,"sku":"NOR-847818557-50g","price":675.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_1-Methyl-1H-pyrazole-4-boronic_Acid.png?v=1782683391"},{"product_id":"isoxazol-4-ylboronic-acid-cas-1008139-25-0","title":"Isoxazol-4-ylboronic Acid | CAS 1008139-25-0 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1008139-25-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e696-473-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD06657892\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CON=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C3H4BNO3\/c6-4(7)3-1-5-8-2-3\/h1-2,6-7H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eHANPIZQMFCWPKY-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e46739468\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₃H₄BNO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e112.88 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to beige crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore refrigerated (2–8 °C) in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003eIsoxazol-4-ylboronic acid\u003c\/strong\u003e (isoxazole-4-boronic acid; (1,2-oxazol-4-yl)boronic acid; 4-isoxazolylboronic acid) is a heteroaromatic boronic acid bearing boron at the 4-position of the isoxazole (1,2-oxazole) ring.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride isoxazol-4-ylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStability and protodeboronation:\u003c\/strong\u003e with boron at C-4 — remote from the ring O and N — it is not one of the fast-decomposing heteroatom-adjacent heteroaryl boronic acids (such as 2-pyridyl or 2-thienyl). It is used directly in DNA-compatible cyanomethylation, where productive chemistry proceeds through Suzuki coupling followed by base-promoted isoxazole fragmentation. As for boronic acids generally, protodeboronation is promoted by strong base, elevated temperature, and prolonged aqueous exposure. Supplied for cold storage under inert atmosphere; a pinacol ester or trifluoroborate is the usual surrogate where a sensitive boronic acid needs extra stability.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e under milder bases and lower temperatures the intact 4-isoxazolyl group transfers to aryl, heteroaryl, and alkenyl halides or triflates to give 4-substituted isoxazoles; stronger base diverts the reagent into the cyanomethylation fragmentation below.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTandem cyanomethylation:\u003c\/strong\u003e a one-pot Pd-catalysed domino sequence — Suzuki coupling, base-promoted isoxazole fragmentation, then deformylation — converts (hetero)aryl halides into arylacetonitriles (ArCH₂CN), the isoxazole serving as a masked cyanomethyl equivalent.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTwo-step cyanomethylation variant:\u003c\/strong\u003e the coupling and the fragmentation are run as separate steps, for substrates incompatible with the high-temperature one-pot conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDNA-compatible cyanomethylation:\u003c\/strong\u003e the tandem process runs on DNA-tagged (hetero)aryl halides and triflates without significant DNA damage, supplying arylacetonitriles and derived arylacetic acids for DNA-encoded library (DEL) screening collections.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam C–N and C–O coupling:\u003c\/strong\u003e as an arylboronic acid it can transfer the 4-isoxazolyl group to amine, amide, and phenol nucleophiles under mild copper-mediated aerobic conditions, without a halide partner.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRhodium-catalysed 1,4-addition:\u003c\/strong\u003e as an arylboronic acid it can add the 4-isoxazolyl group to α,β-unsaturated carbonyl acceptors, with chiral ligands giving enantioenriched products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e as a heteroarylboronic acid, the C–B bond can be oxidised to C–OH under peroxide, persulfate, N-oxide, or photoredox conditions to give isoxazol-4-ol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePinacol ester format:\u003c\/strong\u003e the corresponding pinacol boronate is the form used in the original one-pot arylacetonitrile work and serves as a masked, bench-stable boronate when a less reactive format is preferred.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCovalent fragment for screening:\u003c\/strong\u003e boronic acid coupling reagents are repurposed as directed covalent-fragment libraries for serine hydrolases and related enzymes (autotaxin among the documented examples), the boron orming a reversible covalent adduct with the active-site serine or threonine.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsoxazole building block and bioisostere:\u003c\/strong\u003e installs the isoxazole ring — an established amide and ester bioisostere — at C-4 for pharmaceutical, agrochemical, and heteroaryl-analogue synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"250 mg","offer_id":53520000385361,"sku":"NOR-1008139250-250mg","price":59.8,"currency_code":"EUR","in_stock":true},{"title":"1.0 g","offer_id":53520000418129,"sku":"NOR-1008139250-1g","price":159.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53520000450897,"sku":"NOR-1008139250-5g","price":699.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Isoxazol-4-ylboronic_Acid.png?v=1782683391"},{"product_id":"2-fluorophenylboronic-acid-cas-1993-03-9","title":"2-Fluorophenylboronic Acid | CAS 1993-03-9 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1993-03-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e671-858-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00674013\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=CC=C1F)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BFO2\/c8-6-4-2-1-3-5(6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eQCSLIRFWJPOENV-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734354\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BFO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e139.92 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e101–110 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2-Fluorophenylboronic acid\u003c\/strong\u003e (2-fluorobenzeneboronic acid; o-fluorophenylboronic acid) is an ortho-substituted arylboronic acid with the fluorine adjacent to the boronic acid group.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 2-fluorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStability and protodeboronation:\u003c\/strong\u003e the ortho-fluorine accelerates base-mediated protodeboronation. Phenyl, 3-fluoro-, and 4-fluorophenylboronic acid protodeboronate slowly and at near-identical rates, whereas the ortho-fluorinated isomers, including this one, are markedly faster. As the pathway is base- and pH-dependent, milder bases, active catalyst systems that complete coupling quickly, and the more robust surrogate formats (pinacol ester, MIDA boronate, potassium trifluoroborate) are the usual ways to suppress it. Separately, the ortho-fluorine lowers the boronic acid pKa relative to the parent.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e installs the 2-fluorophenyl group into biaryls and heterobiaryls — scaffolds for pharmaceutical, agrochemical, and materials synthesis — with aryl, heteroaryl, and alkenyl halides and triflates. The small ortho-fluorine adds little steric demand; condition choice follows the stability note above.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRhodium-catalysed enantioselective 1,4-addition:\u003c\/strong\u003e serves as the aryl donor in Rh-catalysed asymmetric conjugate addition to enones, enals, and unsaturated esters; with chiral bisphosphine or diene ligands it sets stereocentres bearing the 2-fluorophenyl group. It also participates in Rh- and Pd-catalysed allylic substitution to give branched allylic products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical building block and impurity reference:\u003c\/strong\u003e catalogued as \"vonoprazan impurity 215\" and used as an impurity reference standard for potassium-competitive acid blocker (P-CAB) gastric-acid drugs, and as a fluorinated aryl building block for SAR libraries and other medicinal-chemistry intermediates. Aromatic fluorine is widely used to block oxidative (CYP-mediated) metabolism at the substituted position and to modulate the pKa and electronics of neighbouring groups.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eArylboron difluoride (ArBF₂) Lewis acids:\u003c\/strong\u003e used in the preparation of aryl-BF₂ species — electron-deficient organoboron Lewis acids of interest as catalysts and building blocks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDiol and saccharide recognition:\u003c\/strong\u003e forms reversible boronate esters with 1,2- and 1,3-diols; the electron-withdrawing ortho-fluorine increases boron Lewis acidity and lowers the pKa, favouring boronate formation. Applied in saccharide sensors, glucose-responsive materials, and boronate-affinity separations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAnion receptors for polymer electrolytes:\u003c\/strong\u003e used to prepare phenylboronic catechol esters studied as Lewis-acidic anion receptors for polymer-electrolyte membranes; among the fluorinated derivatives examined, the 2-fluoro catechol ester gave the largest increase in Lewis acidity, of direct relevance to anion binding in fuel-cell and battery electrolytes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLiquid-crystal materials:\u003c\/strong\u003e Suzuki coupling of this boronic acid gives 2-fluorobiphenyls; laterally fluorinated biphenyls and terphenyls are fundamental building blocks of nematic liquid-crystal mixtures for TFT-LCDs, where ring fluorination tunes dielectric anisotropy, birefringence, and melting point.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam C–N and C–O coupling:\u003c\/strong\u003e as an arylboronic acid it can transfer the 2-fluorophenyl group to amine, amide, and phenol nucleophiles under mild copper-mediated aerobic conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e oxidation of the C–B bond (peroxide, persulfate, N-oxide, or photoredox) replaces boron with a hydroxyl to give 2-fluorophenol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53520275374417,"sku":"NOR-1993039-1g","price":21.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53520275407185,"sku":"NOR-1993039-2g","price":28.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53520275439953,"sku":"NOR-1993039-5g","price":39.9,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53520275472721,"sku":"NOR-1993039-10g","price":59.9,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53520275505489,"sku":"NOR-1993039-25g","price":78.9,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53520275538257,"sku":"NOR-1993039-50g","price":129.8,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53520275571025,"sku":"NOR-1993039-100g","price":219.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53520275603793,"sku":"NOR-1993039-250g","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53520275636561,"sku":"NOR-1993039-500g","price":899.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_2-Fluorophenylboronic_Acid.png?v=1782683391"},{"product_id":"3-chlorophenylboronic-acid-cas-63503-60-6","title":"3-Chlorophenylboronic Acid | CAS 63503-60-6 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e63503-60-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e628-786-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00161354\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC(=CC=C1)Cl)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H6BClO2\/c8-6-3-1-2-5(4-6)7(9)10\/h1-4,9-10H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eSDEAGACSNFSZCU-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734323\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₆BClO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e156.37 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e185–189 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e3-Chlorophenylboronic acid\u003c\/strong\u003e (3-chlorobenzeneboronic acid; m-chlorophenylboronic acid) is a meta-substituted arylboronic acid bearing a chloro substituent at the 3-position of the ring.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 3-chlorophenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e the meta-chloro group is moderately electron-withdrawing and sterically unobtrusive. With no ortho substituent or ring heteroatom adjacent to boron, it sits with the parent and simple 3-\/4-substituted phenylboronic acids at the slow end of the protodeboronation scale, away from the labile ortho-disubstituted, polyfluoro, and 2-heteroaryl classes. Its defining feature is bifunctionality: in a standard Suzuki coupling the boron reacts while the aryl C–Cl is retained as a second handle.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling and sequential functionalisation:\u003c\/strong\u003e installs the 3-chlorophenyl group into biaryls and heterobiaryls from aryl, heteroaryl, and vinyl halides or pseudohalides. The retained meta C–Cl bond then serves as an orthogonal handle for a second Suzuki coupling, Buchwald–Hartwig amination, or palladium-catalysed cyanation, giving stepwise access to polysubstituted biaryls and terphenyls from a single building block. It has also been coupled with dibromo(trifluoromethyl)benzene to give CF₃-substituted chlorobiphenyls.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical building block — vadadustat and PDE4 inhibitors:\u003c\/strong\u003e a documented building block in the synthesis of the HIF-prolyl-hydroxylase (HIF-PHD) inhibitor vadadustat, developed for anaemia of chronic kidney disease, where Suzuki coupling installs the 3-chlorophenyl group onto the pyridine core. It is also used to introduce the 3-chloroaryl fragment into PDE4 (phosphodiesterase-4) inhibitor scaffolds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBiaryl ketones and phthalides:\u003c\/strong\u003e carbonylative Suzuki coupling under carbon monoxide gives biaryl ketones; the compound is also used in the synthesis of phthalide (isobenzofuran-1(3H)-one) scaffolds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1,4-Conjugate addition to ethenesulfonamides:\u003c\/strong\u003e serves as the aryl donor in Rh- or Pd-catalysed conjugate addition to ethenesulfonamides, giving aryl­ethanesulfonamides; the meta-chlorine is retained in the product for further derivatisation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoupling with diazoesters:\u003c\/strong\u003e palladium-catalysed coupling with α-diazoesters proceeds through a metal-carbene migratory insertion to give α-aryl α,β-unsaturated esters (diarylacrylates); chloro- and bromo-substituted arylboronic acids are tolerated and retained intact under these oxidative conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoupling with potassium cyanate:\u003c\/strong\u003e copper-catalysed coupling with potassium cyanate in an alcohol gives aryl carbamates via an aryl isocyanate intermediate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam C–N and C–O coupling:\u003c\/strong\u003e as an arylboronic acid it can transfer the 3-chlorophenyl group to amine, amide, and phenol nucleophiles under mild copper-mediated aerobic conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOxidative ipso-hydroxylation:\u003c\/strong\u003e oxidation of the C–B bond (peroxide, persulfate, N-oxide, or photoredox) replaces boron with a hydroxyl to give 3-chlorophenol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53520436855121,"sku":"NOR-63503606-1g","price":21.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53520436887889,"sku":"NOR-63503606-2g","price":29.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53520436920657,"sku":"NOR-63503606-5g","price":39.9,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53520436953425,"sku":"NOR-63503606-10g","price":49.9,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53520436986193,"sku":"NOR-63503606-25g","price":64.9,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53520437018961,"sku":"NOR-63503606-50g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53520437051729,"sku":"NOR-63503606-100g","price":179.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53520437084497,"sku":"NOR-63503606-250g","price":399.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_3-Chlorophenylboronic_Acid.png?v=1782683428"},{"product_id":"4-formylphenylboronic-acid-cas-87199-17-5","title":"4-Formylphenylboronic Acid | CAS 87199-17-5 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e87199-17-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e617-982-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00151823\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)C=O)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H7BO3\/c9-5-6-1-3-7(4-2-6)8(10)11\/h1-5,10-11H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eVXWBQOJISHAKKM-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e591073\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₇BO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e149.94 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e237–242 °C (lit.) (Sigma)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to light yellow crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Formylphenylboronic acid\u003c\/strong\u003e (4-boronobenzaldehyde; 4-(dihydroxyboryl)benzaldehyde; \u003cem\u003ep\u003c\/em\u003e-formylphenylboronic acid) is a bifunctional arylboronic acid bearing a formyl group para to the boronic acid. The two groups are mutually compatible and can be addressed independently — the boronic acid in C–C cross-coupling, the aldehyde in reductive amination and imine formation — so a single compact reagent supports modular, sequential assembly. The para-formyl group is moderately electron-withdrawing (σp ≈ +0.42), which lowers the boronic acid pKa relative to phenylboronic acid (≈ 8.8–9.0) and favours boronate (diol-binding) formation at lower pH — useful for saccharide and catecholamine recognition. It serves as a building block across pharmaceutical, materials, sensor, and dye-sensitised solar-cell research.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride 4-formylphenylboroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e installs the 4-formylphenyl group into biaryls and heteroaryls, with reactions proceeding even in aqueous media. The aldehyde survives the coupling intact and is then a handle for reductive amination or imine (Schiff-base) condensation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKetone synthesis and oxidative coupling:\u003c\/strong\u003e palladacycle-catalysed cross-coupling with carboxylic anhydrides or acyl chlorides gives aryl ketones; the compound also serves as the aryl nucleophile in palladium-catalysed aerobic oxidative cross-coupling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eipso-substitution of the boron:\u003c\/strong\u003e the C–B bond can be replaced while the aldehyde is retained — copper-mediated ligandless aerobic fluoroalkylation with (per)fluoroalkyl iodides gives 4-(perfluoroalkyl)benzaldehydes; copper-catalysed ipso-nitration gives 4-nitrobenzaldehyde; ligand-free copper-catalysed coupling with nitroarenes furnishes unsymmetrical diaryl ethers (C–O bond, the oxygen derived from water); and chemoselective oxidation of the C–B bond gives 4-hydroxybenzaldehyde.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHantzsch dihydropyridine synthesis:\u003c\/strong\u003e serves as the aldehyde (carbonyl) component in triethylamine-catalysed three-component Hantzsch condensations, giving boronic-acid-substituted 1,4-dihydropyridines that retain a coupling handle.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eScaffold and macrocycle construction:\u003c\/strong\u003e serves as the aryl source in Suzuki aryl–aryl coupling on the upper rim of hexahomotrioxacalix[3]arene and in rhodium-catalysed arylative cyclisation of 1,5-enynes to cyclopentenes and spiro-cyclopentenes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBiocatalytic alkene cleavage:\u003c\/strong\u003e a reagent in the oxidative mono-cleavage of dialkenes catalysed by the fungus \u003cem\u003eTrametes hirsuta\u003c\/em\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical building block:\u003c\/strong\u003e a Suzuki building block for biaryl pharmaceutical intermediates, including the angiotensin-II (AT1) receptor antagonist telmisartan, and for a reported protein-synthesis inhibitor active against Gram-positive bacteria.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSerine-hydrolase engagement and enzyme stabilisation:\u003c\/strong\u003e like other arylboronic acids it reversibly engages the catalytic serine of serine hydrolases — the broader arylboronic-acid chemistry behind reversible inhibition of serine β-lactamases, including the class C enzyme AmpC, in antibiotic-resistance research. The same reversible binding makes it a preferred industrial stabiliser for proteases and lipases in liquid-detergent formulations, markedly more effective than boric acid, suppressing autolysis during storage and releasing the enzyme on dilution in use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDiol recognition and biosensors:\u003c\/strong\u003e the boronic acid binds 1,2- and 1,3-diols, giving a recognition element for saccharides (glucose, fructose) and catecholamines, while the aldehyde anchors the molecule to amine-functionalised supports by Schiff-base condensation (often followed by reduction). Both handles are used together to build boronic-acid-functionalised self-assembled monolayers on electrodes — for example a cysteamine monolayer grafted with the reagent for dopamine sensing — and to functionalise magnetic nanoparticles for catecholamine capture.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDynamic covalent and stimuli-responsive materials:\u003c\/strong\u003e the aldehyde forms reversible imines and acylhydrazones while the boronic acid forms reversible boronate esters, giving doubly dynamic networks; combined with diol- or hydrazide-bearing polymers it yields self-healing gels responsive to pH, glucose, and redox state.\u003cstrong\u003eDye-sensitised solar cells:\u003c\/strong\u003e used to prepare push–pull (D–π–A) sensitisers built on dithiafulvenyl electron-donor units, where the boronic acid builds the conjugated π-bridge by Suzuki coupling and the aldehyde is a condensation handle.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53521158996305,"sku":"NOR-87199175-1g","price":21.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53521159029073,"sku":"NOR-87199175-2g","price":29.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53521159061841,"sku":"NOR-87199175-5g","price":39.9,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53521159094609,"sku":"NOR-87199175-10g","price":54.9,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53521159127377,"sku":"NOR-87199175-25g","price":79.8,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53521159160145,"sku":"NOR-87199175-50g","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53521159192913,"sku":"NOR-87199175-100g","price":229.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53521159225681,"sku":"NOR-87199175-250g","price":499.0,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53521159258449,"sku":"NOR-87199175-500g","price":1025.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Formylphenylboronic_Acid.png?v=1782683428"},{"product_id":"pyridin-3-ylboronic-acid-cas-1692-25-7","title":"Pyridin-3-ylboronic Acid | CAS 1692-25-7 | ≥95%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1692-25-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e605-544-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00674177\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CN=CC=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C5H6BNO2\/c8-6(9)5-2-1-3-7-4-5\/h1-4,8-9H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eABMYEXAYWZJVOV-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734378\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₅H₆BNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e122.92 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e\u0026gt;300 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water; soluble in alcoholic solvents, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature in a tightly sealed container, in a dark place. Protect from moisture and light. May contain varying amounts of boroxine anhydride\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePyridin-3-ylboronic acid\u003c\/strong\u003e (3-pyridineboronic acid, 3-pyridylboronic acid, pyridine-3-boronic acid) is an electron-deficient heteroaryl boronic acid with boron at the pyridine 3-position, two bonds from the ring nitrogen.\u003c\/p\u003e\n\u003cp\u003eIt is frequently isolated and supplied partly as the cyclic anhydride tris(3-pyridyl)boroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStability and coupling behaviour:\u003c\/strong\u003e Whilst the 2-pyridyl isomer the ring nitrogen sits adjacent to boron and drives rapid protodeboronation (the \"2-pyridyl problem\"). In the 3-pyridyl isomer, the C-3 the nitrogen is two bonds removed, so the acid is robust and couples directly under standard Pd(PPh₃)₄ or Pd(dppf)Cl₂ \/ K₂CO₃ conditions, without MIDA or trifluoroborate masking. As with other N-heteroaryls, the Lewis-basic nitrogen can coordinate palladium and slow turnover — including transmetalation and reductive elimination — so bulky electron-rich biarylphosphines are the standard remedy on demanding substrates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e One of the most widely used pyridylboronic acids; installs the 3-pyridyl group onto aryl, heteroaryl, and vinyl halides — e.g. with halogenated quinolines to give 3-(pyridin-3-yl)quinolines and related heterobiaryls. Phosphine-free palladium protocols are also documented.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTandem coupling–annulation:\u003c\/strong\u003e Combines regioselective Suzuki–Miyaura coupling with palladium-catalysed intramolecular aminocarbonylation and annulation to assemble fused nitrogen heterocycles in one sequence.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper-mediated functionalisation:\u003c\/strong\u003e Undergoes copper(II) acetylacetonate–catalysed N-arylation (Chan–Lam-type C–N bond formation) and copper-mediated cyanation, including regioselective cyanation of electron-rich arenes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmaceutical building block:\u003c\/strong\u003e Supplies the 3-pyridyl unit of Bcr–Abl tyrosine-kinase inhibitors such as nilotinib (chronic myeloid leukaemia), installed by Suzuki coupling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal-chemistry motif:\u003c\/strong\u003e The 3-pyridyl group is among the most common nitrogen heterocycles in approved drugs and a frequent phenyl bioisostere: replacing phenyl raises aqueous solubility, adds a hydrogen-bond acceptor, and tempers lipophilicity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunctional and supramolecular polymers:\u003c\/strong\u003e Prepares linear poly(phenylpyridyl) chains by iterative Suzuki coupling and oligopyridyl foldamers that mimic the α-helix twist.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoordination chemistry and framework materials:\u003c\/strong\u003e The pyridyl nitrogen of the products is an N-donor site — a ligand in coordination complexes, a linker in metal–organic frameworks, and the metal-binding element in sensor materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAgrochemical and materials intermediates:\u003c\/strong\u003e Provides cross-coupling access to 3-pyridyl analogue libraries and electron-deficient arylpyridine intermediates for agrochemical and organic-electronics research.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; 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background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53526618767697,"sku":"NOR-1692257-1g","price":23.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53526618800465,"sku":"NOR-1692257-2g","price":32.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53526618833233,"sku":"NOR-1692257-5g","price":49.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53526618866001,"sku":"NOR-1692257-10g","price":65.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53526618898769,"sku":"NOR-1692257-25g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53526618931537,"sku":"NOR-1692257-50g","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53526618964305,"sku":"NOR-1692257-100g","price":249.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53526618997073,"sku":"NOR-1692257-250g","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Pyridin-3-ylboronic_Acid.png?v=1782683428"},{"product_id":"products-1-naphthaleneboronic-acid-cas-13922-41-3","title":"1-Naphthaleneboronic Acid | CAS 13922-41-3 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e13922-41-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e604-119-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00019722\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=CC2=CC=CC=C12)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C10H9BO2\/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10\/h1-7,12-13H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eHUMMCEUVDBVXTQ-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e254532\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₀H₉BO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e171.99 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e208–214 °C (lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eOff-white to beige powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e1-Naphthaleneboronic acid\u003c\/strong\u003e (naphthalen-1-ylboronic acid, α-naphthylboronic acid) is an arylboronic acid bearing the sterically demanding 1-naphthyl group.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride tris(1-naphthyl)boroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e Installs the 1-naphthyl group onto aryl and heteroaryl halides en route to polyaromatic hydrocarbons — binaphthyls, naphthyl-anthracenes, and higher acenes — for organic semiconductors, photovoltaics, and fluorescent dyes. The C-8 peri-hydrogen, across the ring junction from boron at C-1, imposes a steric demand that sets the biaryl dihedral and rotational barrier — a handle for tuning conformation in conjugated materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOLED host materials and blue molecular glasses:\u003c\/strong\u003e Builds naphthyl-anthracene intermediates for spirobenzofluorene host materials in blue OLEDs, and gives 9-(naphthalen-1-yl)anthracene, an amorphous blue-emitting molecular glass in which the bulky 1-naphthyl group suppresses crystallisation and favours glassy thin films.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrganotrifluoroborate and ArBF₂ Lewis acids:\u003c\/strong\u003e Treatment with KHF₂ gives the bench-stable potassium 1-naphthyltrifluoroborate, a convenient precursor to 1-naphthyl boron difluoride (ArBF₂) Lewis acids.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFluorometric saccharide sensing:\u003c\/strong\u003e The naphthalene fluorophore reports reversible boronate-ester formation with 1,2- and 1,3-diols, enabling fluorometric detection of glucose, fructose, and related diol analytes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBifunctional polymers for cellulose hydrolysis:\u003c\/strong\u003e Incorporated into polymers that bind cellulose through boronate esters with the sugar hydroxyls while co-located acid groups cleave glycosidic bonds, depolymerising biomass under milder conditions than direct acid hydrolysis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSerine-enzyme research:\u003c\/strong\u003e As a boronic acid it engages the active-site serine reversibly; 1-naphthaleneboronic acid is a documented AmpC β-lactamase inhibitor used in inhibitor design and mechanistic studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53533428842833,"sku":"NOR-13922413-1g","price":24.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53533428875601,"sku":"NOR-13922413-2g","price":34.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53533428908369,"sku":"NOR-13922413-5g","price":49.9,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53533428941137,"sku":"NOR-13922413-10g","price":64.9,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53533428973905,"sku":"NOR-13922413-25g","price":109.2,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53533429006673,"sku":"NOR-13922413-50g","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53533429039441,"sku":"NOR-13922413-100g","price":239.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53533429072209,"sku":"NOR-13922413-250g","price":315.0,"currency_code":"EUR","in_stock":true},{"title":"500 g","offer_id":53533429104977,"sku":"NOR-13922413-500g","price":580.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_1-Naphthaleneboronic_Acid.png?v=1782683428"},{"product_id":"4-aminophenylboronic-acid-hcl-cas-80460-73-7","title":"(4-Aminophenyl)boronic Acid HCl | CAS 80460-73-7 | ≥95%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e80460-73-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e623-030-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD03001333\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)N)(O)O.Cl\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H8BNO2.ClH\/c8-6-3-1-5(2-4-6)7(9)10;\/h1-4,9-10H,8H2;1H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eQBYGJJSFMOVYOA-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734614\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₉BClNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e173.41 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e195-200 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water, methanol, ethanol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog P\u003csub\u003eow\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e1.035\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥95%. May contain small variable amounts of boron anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months under recommended storage conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore under inert atmosphere at room temperature in a tightly sealed container, in a dark place. Mildly hygroscopic - Protect from moisture and light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e(4-Aminophenyl)boronic acid hydrochloride\u003c\/strong\u003e (4-aminophenylboronic acid HCl, 4-boronoaniline hydrochloride, 4-aminobenzeneboronic acid hydrochloride) is a bifunctional arylboronic acid carrying a para-amino group, supplied as the hydrochloride salt.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the corresponding cyclic anhydride (boroxine) form. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm and handling:\u003c\/strong\u003e The free 4-aminophenylboronic acid is air- and moisture-sensitive, so the compound is supplied as the bench-stable hydrochloride. Protonation holds the aniline as the anilinium ion during storage and coupling; the free aniline is liberated on basic workup.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e Installs the 4-aminophenyl group onto aryl, heteroaryl, and vinyl halides to give 4-amino-substituted biaryls and heterobiaryls. The hydrochloride is the convenient coupling form, with the free aniline recovered after basic workup.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChan–Lam C–N and C–O coupling:\u003c\/strong\u003e As an arylboronic acid it undergoes copper-mediated aerobic coupling with N–H and O–H partners to form arylamines, arylamides, and diaryl ethers; the aniline provides a second site for downstream derivatisation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBifunctional building block:\u003c\/strong\u003e The orthogonal boronic acid and aniline handles support sequential cross-coupling followed by amide formation, reductive amination, diazotisation, or heterocycle construction on one scaffold. The aniline is also the anchor for immobilisation — by amide coupling to polymers and supports or by diazonium grafting onto carbon surfaces — which underpins the affinity and sensor materials below.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMedicinal-chemistry building block:\u003c\/strong\u003e Used in the preparation of chromen-4-ones investigated as DNA-dependent protein kinase (DNA-PK) inhibitors, where Suzuki coupling installs the aminophenyl unit onto the chromone scaffold.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoronate-affinity capture of cis-diol compounds:\u003c\/strong\u003e Anchored to monoliths, magnetic particles, and molecularly imprinted polymers through the aniline, the boronic acid binds cis-diols reversibly — covalent ester formation under basic conditions, release under acid — for enrichment and separation of glycoproteins, nucleosides, catechols, and saccharides in proteomics and sample preparation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGlucose-responsive materials and insulin-release systems:\u003c\/strong\u003e Aminophenylboronic-acid derivatives incorporated into polymers, microgels, and nanoparticles bind saccharide cis-diols reversibly; the resulting charge and swelling changes drive the glucose-responsive behaviour exploited in saccharide sensing and self-regulated insulin-release materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnzyme-free electrochemical sugar sensors:\u003c\/strong\u003e Used to build 4-aminophenylboronic-acid–modified reduced graphene oxide (rGO\/APBA) electrodes, where boronate binding of sugar cis-diols enables non-enzymatic voltammetric detection of fructose, mannose, and glucose, including in fruit-juice samples.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDual NADH and hydrogen-peroxide sensing:\u003c\/strong\u003e H₂O₂-triggered conversion of the aminophenylboronic acid generates adsorbed aminophenol on pre-anodised screen-printed carbon electrodes, giving a non-enzymatic amperometric platform for NADH and H₂O₂ detection.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFluorescent carbon dots:\u003c\/strong\u003e Serves as a boron- and nitrogen-containing precursor for fluorescent carbon dots, applied to the sequential detection of ferric ions and ascorbic acid.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"2.0 g","offer_id":53799729365329,"sku":"NOR-80460737-2g","price":29.2,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53799668220241,"sku":"NOR-80460737-5g","price":45.2,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53799668253009,"sku":"NOR-80460737-10g","price":76.2,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53799668285777,"sku":"NOR-80460737-25g","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53799668318545,"sku":"NOR-80460737-50g","price":229.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53799668351313,"sku":"NOR-80460737-100g","price":429.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Aminophenyl_boronic_Acid_HCl.png?v=1782683428"},{"product_id":"quinolin-5-ylboronic-acid-cas-355386-94-6","title":"Quinolin-5-ylboronic Acid | CAS 355386-94-6 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e355386-94-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e670-357-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD03095058\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=C2C=CC=NC2=CC=C1)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C9H8BNO2\/c12-10(13)8-4-1-5-9-7(8)3-2-6-11-9\/h1-6,12-13H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eNWIJBOCPTGHGIK-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e5153389\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₉H₈BNO₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e172.98 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e144–148 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSlightly soluble in water; soluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%. May contain varying amounts of the corresponding boronic acid anhydrides\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eLight yellow to brown powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore refrigerated (2–8 °C) in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuinolin-5-ylboronic acid\u003c\/strong\u003e (5-quinolineboronic acid, 5-boronoquinoline) is a heteroaryl boronic acid bearing the quinoline scaffold, with boron at the 5-position on the carbocyclic ring.\u003c\/p\u003e\n\u003cp\u003eMay contain small amounts of the cyclic anhydride tris(quinolin-5-yl)boroxine. Under aqueous or basic coupling conditions the two forms re-equilibrate and the impact on yield is minor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePosition and stability:\u003c\/strong\u003e C-5 lies on the carbocyclic (benzene) ring of quinoline, not the pyridine ring. Boron there sits peri to C-4 across the ring junction — a naphthalene-like relationship — while the ring nitrogen lies on the far pyridine ring, remote from boron. Well separated from the nitrogen, the reagent behaves as a carbocyclic-ring arylboronic acid rather than a labile 2-pyridyl-type boron, coupling robustly without the protodeboronation and palladium-coordination liabilities of boron sited on or beside the pyridine ring. The C-4 peri-hydrogen imposes a steric demand on the C-5 biaryl bond, influencing the dihedral of the 5-arylquinoline product.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications and Reactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling:\u003c\/strong\u003e Installs the 5-quinolyl fragment onto aryl, heteroaryl, and vinyl halides to give 5-arylquinolines and related heterobiaryls. Couples under standard conditions — Pd(PPh₃)₄ or Pd(dppf)Cl₂ with K₂CO₃ in aqueous dioxane — and is compatible with nickel-catalysed variants. The benzannulated quinoline contributes a rigid, nitrogen-containing aryl fragment for analogue and materials synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHeterocyclic building block for SAR campaigns:\u003c\/strong\u003e Builds 5-arylquinoline and bis(heterocyclic) scaffolds for structure–activity studies. The 5-quinolyl motif is a rigid, planar, nitrogen-containing biaryl whose ring nitrogen adds a hydrogen-bond acceptor and raises polarity and aqueous solubility relative to naphthalene, making it a favoured aza-naphthalene bioisostere for naphthyl and other fused carbocyclic aromatics in lead optimisation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOLED and optoelectronic materials:\u003c\/strong\u003e The electron-poor, pyridine-type nitrogen makes quinoline a π-deficient, electron-accepting ring with a low-lying LUMO — the property behind its long record in organic electronics, exemplified by the archetypal OLED material tris(8-hydroxyquinolinato)aluminium (Alq₃), itself a quinoline metal chelate. 5-Arylquinolines accessed by Suzuki coupling form a distinct, covalently linked class of quinoline π-systems explored as electron-transport and hole-blocking layers, where the low LUMO promotes electron injection from the cathode and confines holes at the emissive interface. Emission tunes with the electronic character of the C-5 aryl group installed in the coupling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoordination chemistry and metal complexes:\u003c\/strong\u003e The quinoline nitrogen of the coupled products is an N-donor that binds transition metals — iridium, platinum, ruthenium, zinc — to give luminescent and electroluminescent complexes and ditopic bridging ligands for metal–organic framework construction. Quinoline-type N-donor ligands recur throughout phosphorescent and emissive metal-complex design.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFluorescent probes and chemical sensors:\u003c\/strong\u003e The quinoline ring is an intrinsic UV\/visible fluorophore with large, tunable Stokes shifts, its emission shifting with the electronic character of the C-5 substituent. The ring nitrogen acts as a proton-responsive switch — protonation shifts absorption and emission, enabling ratiometric pH sensing, a built-in advantage over carbocyclic fluorophores. Nitrogen coordination further supports colorimetric and fluorescent detection of metal cations such as Zn²⁺, Cu²⁺, and Fe³⁺, with use in biological imaging and environmental monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\n\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\n\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"250 mg","offer_id":53683554877777,"sku":"NOR-355386946-250mg","price":37.2,"currency_code":"EUR","in_stock":true},{"title":"1.0 g","offer_id":53534811652433,"sku":"NOR-355386946-1g","price":55.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53534811685201,"sku":"NOR-355386946-2g","price":105.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53534811717969,"sku":"NOR-355386946-5g","price":249.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53534811750737,"sku":"NOR-355386946-10g","price":475.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53534811783505,"sku":"NOR-355386946-25g","price":1020.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Quinolin-5-ylboronic_Acid.png?v=1782683428"},{"product_id":"potassium-phenyltrifluoroborate-cas-153766-81-5","title":"Potassium Phenyltrifluoroborate | CAS 153766-81-5 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e153766-81-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e627-190-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01318172\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003e[B-](C1=CC=CC=C1)(F)(F)F.[K+]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H5BF3.K\/c8-7(9,10)6-4-2-1-3-5-6;\/h1-5H;\/q-1;+1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eDVAFPKUGAUFBTJ-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e23675248\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₅BF₃K\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e184.01 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e296–301 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in methanol, acetone, acetonitrile, DMF. Poorly soluble in nonpolar organic solvents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePotassium phenyltrifluoroborate (PhBF₃K)\u003c\/strong\u003e is the potassium salt of the phenyltrifluoroborate anion, an air- and moisture-stable organoboron reagent that transfers a phenyl group in carbon–carbon, carbon–oxygen and carbon–nitrogen bond formation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Scientific Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura cross-coupling.\u003c\/strong\u003e PhBF₃K is the phenylating partner in palladium-catalysed Suzuki–Miyaura coupling across a wide range of electrophiles: benzylic chlorides, giving diarylmethanes in water; dihalogenated heteroarenes, arylating an isothiazole regiospecifically; aryl sulfamates, coupling at a carbon–oxygen bond; and 2-bromoglycals, furnishing 2-C-aryl branched carbohydrates. The coupling tolerates sensitive functionality: an azide on a bromoconduritol survives the reaction and is carried into a subsequent click cycloaddition.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHydrolytic slow release.\u003c\/strong\u003e In palladium coupling the trifluoroborate does not itself transfer the phenyl group to the metal; it hydrolyses to phenylboronic acid under the reaction conditions, and that boronic acid is the active partner. Matching this release to the rate of catalytic turnover keeps the boronic acid from accumulating, suppressing oxidative homocoupling and protodeboronation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRhodium-catalysed conjugate addition.\u003c\/strong\u003e Under rhodium catalysis PhBF₃K adds the phenyl group to the β-position of α,β-unsaturated ketones; with chiral ligands the conjugate addition to cyclohexenone gives 3-phenylcyclohexanone in high enantioselectivity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper-catalysed amination.\u003c\/strong\u003e Copper catalysis couples aryltrifluoroborates with nitrogen nucleophiles: Chan–Lam-type N-arylation joins them to amines, and reaction with aqueous ammonia delivers primary arylamines.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOxidative hydroxylation.\u003c\/strong\u003e Treatment with hydrogen peroxide and a citric-acid catalyst in water converts PhBF₃K to phenol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCopper-catalysed carboesterification.\u003c\/strong\u003e PhBF₃K is among the trifluoroborates that act as the carbon source in a copper-catalysed three-component addition of dienes and carboxylic acids, giving allylic esters.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLewis-acid arylation of acetals.\u003c\/strong\u003e Under boron trifluoride activation, aryltrifluoroborates add to acetal-derived oxocarbenium ions, replacing one alkoxy group with the aryl group to give substituted ethers.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther applications.\u003c\/strong\u003e The phenyltrifluoroborate anion serves as a weakly coordinating counterion in functional salts, including photoresponsive spin-crossover iron(III) complexes and fluorescent imidazolium salts.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53504380043601,"sku":"NOR-153766815-1g","price":25.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53504380076369,"sku":"NOR-153766815-2g","price":34.9,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53504380109137,"sku":"NOR-153766815-5g","price":43.2,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53504380141905,"sku":"NOR-153766815-10g","price":67.2,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53504380174673,"sku":"NOR-153766815-25g","price":89.2,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53504380207441,"sku":"NOR-153766815-50g","price":129.2,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53504380240209,"sku":"NOR-153766815-100g","price":249.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53504380272977,"sku":"NOR-153766815-250g","price":509.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Potassium_Phenyltrifluoroborate.png?v=1782683467"},{"product_id":"4-carboxyphenylboronic-acid-cas-14047-29-1-97","title":"4-Carboxyphenylboronic acid | CAS 14047-29-1 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e14047-29-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e604-189-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00151801\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eB(C1=CC=C(C=C1)C(=O)O)(O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C7H7BO4\/c9-7(10)5-1-3-6(4-2-5)8(11)12\/h1-4,11-12H,(H,9,10)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eSIAVMDKGVRXFAX-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e312183\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₇H₇BO₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e165.94 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e220 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in alcoholic solvents, acetonitrile, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%. May contain varying amounts of the corresponding boronic acid anhydrides.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4-Carboxyphenylboronic acid\u003c\/strong\u003e (4-boronobenzoic acid) is a bifunctional arylboronic acid. Its boronic acid recognises diols and acts as a cross-coupling nucleophile. Its carboxyl is derivatised to amides or coordinated to metal nodes, leaving boron free to react. This orthogonality makes it a para-carboxyphenyl building block for biaryls, surfaces and functional materials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSolution behaviour.\u003c\/strong\u003e Under anhydrous conditions arylboronic acids equilibrate with their cyclic trimeric anhydrides, the boroxines. In water the Lewis-acidic boron ionises to an anionic trihydroxyboronate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReversible diol recognition.\u003c\/strong\u003e The boronic acid binds cis-1,2- and 1,3-diols, forming five- and six-membered cyclic boronate esters. The boron centre converts from a neutral trigonal-planar form to an anionic tetrahedral ester. Binding is reversible and pH-dependent, strengthening as the medium turns basic. Acid or a competing diol releases the bound diol. Unsubstituted phenylboronic acid has a pKa near nine. Ring substituents shift this pKa, correlating with Hammett constants. Affinity tracks diol structure: catechols and the polyol sorbitol bind strongly. Fructose binds far more strongly than glucose, given its greater furanose abundance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSaccharide and glycan recognition.\u003c\/strong\u003e As synthetic diol receptors, arylboronic acids serve as lectin mimics for sugars and glycans. They bind monosaccharides, glycoproteins and glycated proteins. Unlike protein lectins, they are stable, inexpensive and oxygen-independent. These properties underpin boronic-acid glucose sensing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoronate-affinity capture.\u003c\/strong\u003e Immobilised through its carboxyl, the boronic acid becomes a boronate-affinity ligand. Coupled to lysine residues, it forms a di-boronate resin for affinity chromatography. The resin binds cis-diol species under base and releases them under acid. It has captured deoxyfructosylated peptides, early markers of glycation, from serum-albumin digests. Further affinity targets include nucleosides, nucleotides, nucleic acids and carbohydrates.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResponsive and self-healing materials.\u003c\/strong\u003e The reversible boronate ester also crosslinks stimuli-responsive polymers. Grafted onto poly(2-hydroxyethyl methacrylate) through its carboxyl, the compound gives a dual pH- and glucose-responsive material. It binds glucose at physiological pH, its aggregates dissociating into unimers around the boron ionisation. Diol exchange renders such boronate networks self-healing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFramework-tethered sensing.\u003c\/strong\u003e As a bifunctional linker it builds luminescent metal–organic frameworks. Tethered through its carboxyl to an amino-functionalised zirconium framework, the pendant boron binds sialic acid. Recognition of its triol switches the framework fluorescence, giving a sialic-acid sensor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther applications.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuzuki–Miyaura coupling.\u003c\/strong\u003e Arylboronic acids are the standard nucleophilic partners for biaryl synthesis. Here the boronic acid couples to an aryl bromide over recyclable graphene-supported palladium. The carboxyl is carried through to a carboxy-biaryl. Such couplings reach industrial scale, as in the fungicide boscalid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling.\u003c\/strong\u003e Arylboronic acids arylate amines and phenols under copper catalysis, forming C–N and C–O bonds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidation to phenols.\u003c\/strong\u003e Peroxide-type oxidants convert arylboronic acids to the corresponding phenols by 1,2-aryl migration to oxygen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53504598147409,"sku":"NOR-14047291-1g","price":24.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53504598180177,"sku":"NOR-14047291-2g","price":29.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53504598212945,"sku":"NOR-14047291-5g","price":43.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53504598245713,"sku":"NOR-14047291-10g","price":59.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53504598278481,"sku":"NOR-14047291-25g","price":74.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53504598311249,"sku":"NOR-14047291-50g","price":109.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53504598344017,"sku":"NOR-14047291-100g","price":179.0,"currency_code":"EUR","in_stock":true},{"title":"250 g","offer_id":53504598376785,"sku":"NOR-14047291-250g","price":389.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_4-Carboxyphenylboronic_acid.png?v=1782683467"},{"product_id":"potassium-4-fluorophenyltrifluoroborate-cas-192863-35-7","title":"Potassium (4-Fluorophenyl)trifluoroborate | CAS 192863-35-7 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e192863-35-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e681-607-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD01318170\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003e[B-](C1=CC=C(C=C1)F)(F)(F)F.[K+]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H4BF4.K\/c8-6-3-1-5(2-4-6)7(9,10)11;\/h1-4H;\/q-1;+1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003ePXKNUQDMYBUYSZ-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e23677644\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₄BF₄K\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e202.0 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e290–292 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water, methanol, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore at room temperature in a tightly sealed container under inert atmosphere\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePotassium (4-fluorophenyl)trifluoroborate\u003c\/strong\u003e is an aryltrifluoroborate salt. It is a bench-stable surrogate for 4-fluorophenylboronic acid. The boron is four-coordinate, anionic and not Lewis acidic. The reagent is an air- and moisture-stable, ionic crystalline solid.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura coupling.\u003c\/strong\u003e The reagent is a 4-fluorophenyl donor for Suzuki–Miyaura cross-coupling. Under aqueous or protic conditions it hydrolyses to the boronic acid. That boronic acid then transmetalates to the metal. It couples with aryl and heteroaryl bromides and chlorides to give 4-fluorobiaryls.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSlow release.\u003c\/strong\u003e The 4-fluorophenyl salt needs acid catalysis for efficient hydrolysis. Under basic coupling conditions it therefore hydrolyses slowly. Gearing this slow release to catalytic turnover keeps the free boronic acid low. The low concentration suppresses oxidative homocoupling and protodeboronation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNickel-catalysed coupling.\u003c\/strong\u003e Aryltrifluoroborates couple with phenol-derived electrophiles under earth-abundant nickel catalysis. Aryl mesylates and carbonates serve as partners. The metal activates the carbon–oxygen bond by oxidative addition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eC–H arylation.\u003c\/strong\u003e Aryltrifluoroborates arylate arene C–H bonds without a prehalogenated partner. Indoles couple at C2 to give 2-arylindoles. A copper oxidant turns over the catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative Heck.\u003c\/strong\u003e The salt arylates alkenes to give arylated alkenes. Acrylates give cinnamates. p-Benzoquinone reoxidises the catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium conjugate addition.\u003c\/strong\u003e Potassium organotrifluoroborates add 1,4 to enones under rhodium catalysis. Asymmetric variants proceed at room temperature.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKetone synthesis.\u003c\/strong\u003e They couple with aromatic aldehydes to give ketones. The reaction uses acetone as a hydride acceptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarbonyl arylation.\u003c\/strong\u003e Aryltrifluoroborates add to aldehydes by 1,2-addition. The reaction gives secondary benzylic alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImine arylation.\u003c\/strong\u003e Potassium organotrifluoroborates add to N-sulfonyl ketimines. Asymmetric variants give chiral amines.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis amine synthesis.\u003c\/strong\u003e Trifluoroacetic acid promotes addition to imines and enamines. The reaction gives amines with no metal catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling.\u003c\/strong\u003e Copper(II) acetate couples aryltrifluoroborates with amines and anilines to give arylamines. It also couples them with alcohols and phenols to give aryl ethers. Oxygen is the oxidant.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"250 mg","offer_id":53684092928337,"sku":"NOR-192863357-250mg","price":23.2,"currency_code":"EUR","in_stock":true},{"title":"1.0 g","offer_id":53510042485073,"sku":"NOR-192863357-1g","price":30.0,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53510042517841,"sku":"NOR-192863357-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53510042550609,"sku":"NOR-192863357-5g","price":69.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53510042583377,"sku":"NOR-192863357-10g","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53510042616145,"sku":"NOR-192863357-25g","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53510042648913,"sku":"NOR-192863357-50g","price":249.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53510042681681,"sku":"NOR-192863357-100g","price":379.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Potassium_4-Fluorophenyl_trifluoroborate.png?v=1782683467"},{"product_id":"potassium-4-bromophenyltrifluoroborate-cas-374564-35-9","title":"Potassium (4-Bromophenyl)trifluoroborate | CAS 374564-35-9 | ≥97%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e374564-35-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e624-815-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD02093978\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003e[B-](C1=CC=C(C=C1)Br)(F)(F)F.[K+]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C6H4BBrF3.K\/c8-6-3-1-5(2-4-6)7(9,10)11;\/h1-4H;\/q-1;+1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eYTSKPQQWISZEQO-UHFFFAOYSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e23674779\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₆H₄BBrF₃K\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e262.91 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e\u0026gt;300 °C (dec., lit.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water, methanol, DMF, DMSO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥97%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to off-white crystalline powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2931.90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eStore in a cool, dry place in a tightly sealed container, protected from moisture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\n\u003cp\u003e\u003cstrong\u003ePotassium (4-bromophenyl)trifluoroborate\u003c\/strong\u003e is an aryltrifluoroborate salt. It is a bench-stable surrogate for 4-bromophenylboronic acid. The boron is four-coordinate, anionic and not Lewis acidic. The reagent is an air- and moisture-stable, ionic crystalline solid.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuzuki–Miyaura coupling.\u003c\/strong\u003e The boron is a nucleophilic partner in Suzuki–Miyaura cross-coupling. Under aqueous or protic conditions the salt hydrolyses to the boronic acid. The boronic acid transmetalates to palladium. It then couples with an aryl or heteroaryl electrophile.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBifunctional handle.\u003c\/strong\u003e The ring also carries an aryl carbon–bromine bond. This bond is a reactive cross-coupling electrophile. The trifluoroborate is a robust protected boron group. It tolerates conditions that degrade free boronic acids. The boron and the bromide are orthogonal handles. Their combination supports sequential functionalisation toward terphenyls and extended biaryls.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFurther applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eC–H arylation.\u003c\/strong\u003e Aryltrifluoroborates arylate arene C–H bonds without a prehalogenated partner. Indoles couple at C2 to give 2-arylindoles. A copper oxidant turns over the catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative Heck.\u003c\/strong\u003e The salt arylates alkenes to give arylated alkenes. Acrylates give cinnamates. p-Benzoquinone reoxidises the catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRhodium conjugate addition.\u003c\/strong\u003e Potassium organotrifluoroborates add 1,4 to enones under rhodium catalysis. Asymmetric variants proceed at room temperature.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKetone synthesis.\u003c\/strong\u003e They couple with aromatic aldehydes to give ketones. The reaction uses acetone as a hydride acceptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCarbonyl arylation.\u003c\/strong\u003e Aryltrifluoroborates add to aldehydes by 1,2-addition. The reaction gives secondary benzylic alcohols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImine arylation.\u003c\/strong\u003e Potassium organotrifluoroborates add to N-sulfonyl ketimines. Asymmetric variants give chiral amines.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePetasis amine synthesis.\u003c\/strong\u003e Trifluoroacetic acid promotes addition to imines and enamines. The reaction gives amines with no metal catalyst.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChan–Lam coupling.\u003c\/strong\u003e Copper(II) acetate couples aryltrifluoroborates with amines and anilines to give arylamines. It also couples them with alcohols and phenols to give aryl ethers. Oxygen is the oxidant.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFurther Reading\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor boronic acids, boronic esters, protodeboronation, boroxine content, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: \u003ca href=\"https:\/\/www.norrchemica.com\/blogs\/lab-journal\/boron-reagent-selection-suzuki-miyaura-coupling\"\u003eChoosing Your Boron Source for Suzuki–Miyaura Coupling\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e  \u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"1.0 g","offer_id":53510186860881,"sku":"NOR-374564359-1g","price":29.9,"currency_code":"EUR","in_stock":true},{"title":"2.0 g","offer_id":53510186893649,"sku":"NOR-374564359-2g","price":45.0,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":53510186926417,"sku":"NOR-374564359-5g","price":64.0,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":53510186959185,"sku":"NOR-374564359-10g","price":97.0,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":53510186991953,"sku":"NOR-374564359-25g","price":134.0,"currency_code":"EUR","in_stock":true},{"title":"50 g","offer_id":53510187024721,"sku":"NOR-374564359-50g","price":249.0,"currency_code":"EUR","in_stock":true},{"title":"100 g","offer_id":53510187057489,"sku":"NOR-374564359-100g","price":449.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Potassium_4-Bromophenyl_trifluoroborate.png?v=1782683467"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/collections\/Organoboron_compounds_collection.png?v=1781804429","url":"https:\/\/www.norrchemica.com\/collections\/organoboron-compounds.oembed?page=3","provider":"NorrChemica","version":"1.0","type":"link"}