{"product_id":"copper-ii-trifluoromethanesulfonate-cas-34946-82-2","title":"Copper(II) trifluoromethanesulfonate | CAS 34946-82-2 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e34946-82-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e252-300-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00077492\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eC(F)(F)(F)S(=O)(=O)[O-].C(F)(F)(F)S(=O)(=O)[O-].[Cu+2]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/2CHF3O3S.Cu\/c2*2-1(3,4)8(5,6)7;\/h2*(H,5,6,7);\/q;;+2\/p-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eSBTSVTLGWRLWOD-UHFFFAOYSA-L\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2734996\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₂CuF₆O₆S₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e361.7 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥300 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eWhite to grey to blue powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2904.99\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333;\"\u003eStore in a cool, dry place in a tightly sealed container under an inert atmosphere. Protect from moisture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eCopper(II) trifluoromethanesulfonate\u003c\/strong\u003e (copper(II) triflate, Cu(OTf)₂) is the copper(II) salt of trifluoromethanesulfonic acid. In organic synthesis it is used as a catalyst, either on its own or combined with chiral nitrogen ligands, such as diamines, oxazolines and bis(oxazolines), for enantioselective reactions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMannich-type reactions.\u003c\/strong\u003e With a chiral diamine ligand, Cu(OTf)₂ catalyses enantioselective Mannich-type reactions of \u003cem\u003eN\u003c\/em\u003e-acylimino esters with silyl enol ethers and with alkyl vinyl ethers. The products are \u003cem\u003eN\u003c\/em\u003e-acylated α-amino acid esters with a carbonyl group in the side chain. The method has been applied to the synthesis of an inhibitor of ceramide trafficking.\u003c\/p\u003e\n\u003cdiv style=\"margin:8px 0 18px 0;\"\u003e\n\u003cdiv style=\"display:flex;flex-wrap:wrap;align-items:center;justify-content:flex-start;gap:2px;\"\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"200px\" height=\"110px\" viewbox=\"0 0 200 110\"\u003e\u003cpath d=\"M 185.7,61.0 L 163.7,48.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 163.7,48.2 L 146.4,58.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 136.9,58.2 L 119.6,48.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 121.5,49.3 L 121.6,28.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 117.7,49.3 L 117.7,28.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 119.6,48.2 L 97.6,60.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 97.6,60.9 L 79.7,50.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 97.6,56.5 L 81.6,47.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 71.6,50.5 L 53.6,60.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 51.7,59.8 L 51.7,81.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 55.5,59.8 L 55.5,81.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 53.6,60.9 L 31.6,48.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 164.8,48.9 L 163.7,48.2 L 162.8,48.7\"\u003e\u003c\/path\u003e\u003cpath d=\"M 120.5,48.7 L 119.6,48.2 L 118.5,48.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 98.7,60.3 L 97.6,60.9 L 96.7,60.4\"\u003e\u003c\/path\u003e\u003cpath d=\"M 54.5,60.3 L 53.6,60.9 L 52.5,60.2\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"141.6\" y=\"65.1\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"119.7\" y=\"27.0\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"75.6\" y=\"52.4\" text-anchor=\"middle\"\u003eN\u003c\/text\u003e\u003ctext x=\"53.6\" y=\"90.5\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"25.5\" y=\"49.3\" text-anchor=\"middle\"\u003eR¹\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;font-size:20px;padding:0 4px;\"\u003e+\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"120px\" height=\"110px\" viewbox=\"0 0 120 110\"\u003e\u003cpath d=\"M 83.3,38.8 L 83.4,57.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 80.6,38.8 L 80.6,57.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 82.0,57.1 L 70.3,63.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 61.9,64.0 L 50.1,57.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 82.0,57.1 L 94.6,64.4\"\u003e\u003c\/path\u003e\u003cpath d=\"M 81.4,57.5 L 82.0,57.1 L 82.6,57.5\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"66.1\" y=\"70.6\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"48.1\" y=\"61.4\" text-anchor=\"end\"\u003eMe₃Si\u003c\/text\u003e\u003ctext x=\"104.0\" y=\"73.5\" text-anchor=\"middle\"\u003eR²\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003cdiv style=\"display:flex;flex-direction:column;align-items:center;justify-content:center;min-width:90px;max-width:150px;padding:0 4px;text-align:center;font-size:12px;line-height:1.3;\"\u003e\n\u003cdiv\u003eCu(OTf)₂ (cat.)\u003c\/div\u003e\n\u003cdiv style=\"font-size:30px;line-height:1;\"\u003e⟶\u003c\/div\u003e\n\u003cdiv\u003echiral diamine\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"220px\" height=\"150px\" viewbox=\"0 0 220 150\"\u003e\u003cpath d=\"M 202.8,60.9 L 178.6,47.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 178.6,47.1 L 159.4,58.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 149.7,58.3 L 130.4,47.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 132.5,48.4 L 132.4,24.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 128.3,48.4 L 128.2,24.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 130.4,47.2 L 106.3,61.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 106.3,61.1 L 86.3,49.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 78.0,49.7 L 58.0,61.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 55.9,60.0 L 56.0,83.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 60.1,60.0 L 60.1,83.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 58.0,61.2 L 33.8,47.3\"\u003e\u003c\/path\u003e\u003cpath d=\"M 106.3,61.1 L 106.3,89.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 106.3,89.0 L 130.5,102.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 130.5,105.3 L 150.8,93.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 128.4,101.7 L 148.7,89.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 130.5,102.9 L 130.5,125.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 179.9,47.8 L 178.6,47.1 L 177.7,47.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 131.3,47.7 L 130.4,47.2 L 129.2,47.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 59.0,60.7 L 58.0,61.2 L 56.8,60.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 106.3,87.6 L 106.3,89.0 L 107.5,89.7\"\u003e\u003c\/path\u003e\u003cpath d=\"M 129.3,102.2 L 130.5,102.9 L 130.5,104.0\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"154.5\" y=\"65.2\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"130.3\" y=\"23.5\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"78.5\" y=\"51.5\" text-anchor=\"start\"\u003eNH\u003c\/text\u003e\u003ctext x=\"58.1\" y=\"93.3\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"27.8\" y=\"48.6\" text-anchor=\"middle\"\u003eR¹\u003c\/text\u003e\u003ctext x=\"154.6\" y=\"93.1\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"130.6\" y=\"141.0\" text-anchor=\"middle\"\u003eR²\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp style=\"font-size:12px;margin:4px 0 0 0;\"\u003e\u003cem\u003eMannich-type reaction of an \u003cem\u003eN\u003c\/em\u003e-acylimino ester (left) with a silyl enol ether (centre) gives an \u003cem\u003eN\u003c\/em\u003e-acylated α-amino acid ester (right).\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eHenry reaction.\u003c\/strong\u003e In the Henry (nitroaldol) reaction, nitromethane adds to an aldehyde to give a β-nitro alcohol. Complexes of Cu(OTf)₂ with chiral oxazoline ligands catalyse the asymmetric Henry reaction of aldehydes with nitromethane.\u003c\/p\u003e\n\u003cdiv style=\"margin:8px 0 18px 0;\"\u003e\n\u003cdiv style=\"display:flex;flex-wrap:wrap;align-items:center;justify-content:flex-start;gap:2px;\"\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"90px\" height=\"90px\" viewbox=\"0 0 90 90\"\u003e\u003cpath d=\"M 63.7,20.0 L 63.7,55.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 57.5,20.0 L 57.6,51.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 63.7,55.2 L 32.5,73.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 63.7,53.4 L 63.7,55.2 L 62.1,56.1\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"63.7\" y=\"18.4\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"22.2\" y=\"82.9\" text-anchor=\"middle\"\u003eR\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;font-size:20px;padding:0 4px;\"\u003e+\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;font-size:14px;padding:0 4px;\"\u003eCH₃NO₂\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003cdiv style=\"display:flex;flex-direction:column;align-items:center;justify-content:center;min-width:90px;max-width:150px;padding:0 4px;text-align:center;font-size:12px;line-height:1.3;\"\u003e\n\u003cdiv\u003eCu(OTf)₂ (cat.)\u003c\/div\u003e\n\u003cdiv style=\"font-size:30px;line-height:1;\"\u003e⟶\u003c\/div\u003e\n\u003cdiv\u003echiral oxazoline\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"170px\" height=\"120px\" viewbox=\"0 0 170 120\"\u003e\u003cpath d=\"M 136.3,83.1 L 111.1,68.4\"\u003e\u003c\/path\u003e\u003cpath d=\"M 111.1,68.4 L 111.2,38.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 111.1,68.4 L 80.7,85.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 80.7,85.9 L 54.8,70.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 53.1,62.9 L 53.1,38.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 47.8,62.9 L 47.8,38.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 46.0,70.8 L 27.1,81.7\"\u003e\u003c\/path\u003e\u003cpath d=\"M 82.2,85.0 L 80.7,85.9 L 79.4,85.1\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"137.8\" y=\"90.2\" text-anchor=\"start\"\u003eOH\u003c\/text\u003e\u003ctext x=\"111.2\" y=\"31.6\" text-anchor=\"middle\"\u003eR\u003c\/text\u003e\u003ctext x=\"52.4\" y=\"72.5\" text-anchor=\"middle\"\u003eN⁺\u003c\/text\u003e\u003ctext x=\"50.5\" y=\"37.5\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"22.0\" y=\"90.0\" text-anchor=\"middle\"\u003eO⁻\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp style=\"font-size:12px;margin:4px 0 0 0;\"\u003e\u003cem\u003eHenry reaction of an aldehyde with nitromethane gives a β-nitro alcohol.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eFriedel–Crafts reactions.\u003c\/strong\u003e With chiral bis(oxazoline) ligands, Cu(OTf)₂ catalyses enantioselective Friedel–Crafts additions of indoles to \u003cem\u003eN\u003c\/em\u003e-sulfonyl aldimines. The products are optically active 3-indolylmethanamine derivatives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAddition of trimethylsilyl cyanide.\u003c\/strong\u003e Cu(OTf)₂ catalyses the addition of trimethylsilyl cyanide (TMSCN) to a range of aldehydes and ketones. The products are cyanohydrins protected as their trimethylsilyl ethers.\u003c\/p\u003e\n\u003cdiv style=\"margin:8px 0 18px 0;\"\u003e\n\u003cdiv style=\"display:flex;flex-wrap:wrap;align-items:center;justify-content:flex-start;gap:2px;\"\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"110px\" height=\"110px\" viewbox=\"0 0 110 110\"\u003e\u003cpath d=\"M 57.6,38.6 L 57.6,63.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 53.4,38.6 L 53.3,63.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 55.5,61.7 L 76.3,73.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 55.5,61.7 L 30.8,76.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 56.5,62.3 L 55.5,61.7 L 54.2,62.4\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"55.5\" y=\"37.5\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"86.2\" y=\"83.2\" text-anchor=\"middle\"\u003eR¹\u003c\/text\u003e\u003ctext x=\"24.7\" y=\"83.2\" text-anchor=\"middle\"\u003eR²\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003cdiv style=\"display:flex;flex-direction:column;align-items:center;justify-content:center;min-width:90px;max-width:150px;padding:0 4px;text-align:center;font-size:12px;line-height:1.3;\"\u003e\n\u003cdiv\u003eMe₃SiCN\u003c\/div\u003e\n\u003cdiv style=\"font-size:30px;line-height:1;\"\u003e⟶\u003c\/div\u003e\n\u003cdiv\u003eCu(OTf)₂ (cat.)\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"170px\" height=\"130px\" viewbox=\"0 0 170 130\"\u003e\u003cpath d=\"M 23.9,43.5 L 41.8,53.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 25.8,40.2 L 43.7,50.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 22.0,46.8 L 39.9,57.1\"\u003e\u003c\/path\u003e\u003cpath d=\"M 41.8,53.8 L 63.7,66.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 63.7,66.5 L 73.5,83.3\"\u003e\u003c\/path\u003e\u003cpath d=\"M 63.7,66.5 L 51.1,88.4\"\u003e\u003c\/path\u003e\u003cpath d=\"M 63.7,66.5 L 80.9,56.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 90.4,56.5 L 104.1,64.4\"\u003e\u003c\/path\u003e\u003cpath d=\"M 40.9,53.3 L 41.8,53.8 L 42.9,54.5\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"19.9\" y=\"45.4\" text-anchor=\"middle\"\u003eN\u003c\/text\u003e\u003ctext x=\"79.9\" y=\"97.8\" text-anchor=\"middle\"\u003eR¹\u003c\/text\u003e\u003ctext x=\"47.6\" y=\"97.8\" text-anchor=\"middle\"\u003eR²\u003c\/text\u003e\u003ctext x=\"85.7\" y=\"58.0\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003ctext x=\"109.6\" y=\"70.6\" text-anchor=\"start\"\u003eSiMe₃\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp style=\"font-size:12px;margin:4px 0 0 0;\"\u003e\u003cem\u003eAddition of trimethylsilyl cyanide to an aldehyde or ketone (left) gives the trimethylsilyl ether of the cyanohydrin (right).\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eAnnulative amination and carbazole synthesis.\u003c\/strong\u003e Cu(OTf)₂ is also used as a catalyst for annulative amination, and for the synthesis of carbazoles by intramolecular oxidative C–N bond formation with a hypervalent iodine reagent.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK only: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"5.0 g","offer_id":55164430516561,"sku":"NOR-34946822-5g","price":74.8,"currency_code":"EUR","in_stock":true},{"title":"10 g","offer_id":55164430549329,"sku":"NOR-34946822-10g","price":89.2,"currency_code":"EUR","in_stock":true},{"title":"25 g","offer_id":55164430582097,"sku":"NOR-34946822-25g","price":109.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_Copper_II_Trifluoromethanesulfonate.png?v=1791051999","url":"https:\/\/www.norrchemica.com\/products\/copper-ii-trifluoromethanesulfonate-cas-34946-82-2","provider":"NorrChemica","version":"1.0","type":"link"}