{"product_id":"d-luciferin-cas-2591-17-5","title":"D-Luciferin | CAS 2591-17-5 | ≥98%","description":"\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eTechnical Specifications\u003c\/h3\u003e\u003c\/div\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 0.95em; border: 1px solid #e4e8f0; border-top: none; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2591-17-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eEC \/ EINECS Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e219-981-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMDL Number\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eMFCD00042929\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSMILES\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eC1[C@@H](N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)O\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChI\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eInChI=1S\/C11H8N2O3S2\/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16\/h1-3,7,14H,4H2,(H,15,16)\/t7-\/m1\/s1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eInChIKey\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0; word-break: break-all;\"\u003eBJGNCJDXODQBOB-SSDOTTSWSA-N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e92934\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eC₁₁H₈N₂O₃S₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e280.32 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e190 °C (dec.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eSolubility\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eSoluble in DMSO (10 mg\/mL), DMF, methanol, acetone, ethyl acetate and alkaline aqueous solutions. Slightly soluble in water at pH 6.5.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eLog Pow\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e-0.28\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e≥98%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003ePhysical Form\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003ePale yellow powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eHS Code\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003e2934.20\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; border-bottom: 1px solid #e4e8f0; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333; border-bottom: 1px solid #e4e8f0;\"\u003eRetest period: 36 months from date of manufacture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 9px 16px; font-weight: 600; color: #002147; width: 200px; background: #f7f8fb; font-size: 0.95em; vertical-align: top;\"\u003eStorage Conditions\u003c\/td\u003e\n\u003ctd style=\"padding: 9px 16px; color: #333;\"\u003eStore frozen (below 0 °C) in a tightly sealed container, protected from light.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eProduct Description \u0026amp; Scientific Applications\u003c\/h3\u003e\u003c\/div\u003e\n\u003cdiv style=\"padding: 16px 20px; border: 1px solid #e4e8f0; border-top: none; font-family: Georgia, 'Times New Roman', serif; font-size: 0.95em; line-height: 1.65; color: #333;\"\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eD-Luciferin\u003c\/strong\u003e (D-LH2) is the substrate of firefly luciferase, the light-producing enzyme of the firefly \u003cem\u003ePhotinus pyralis\u003c\/em\u003e. It consists of a 6-hydroxybenzothiazole joined to a thiazoline carboxylic acid, with the (S) configuration at C-4.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe light reaction.\u003c\/strong\u003e Firefly luciferase needs D-luciferin, ATP, oxygen and a metal ion, usually Mg²⁺. In the first step, the enzyme joins D-luciferin to AMP from ATP and releases pyrophosphate. Oxygen then reacts with this luciferyl adenylate; the product loses carbon dioxide and gives oxyluciferin in an excited state, which emits light centred near 560 nm.\u003c\/p\u003e\n\u003cdiv style=\"margin:8px 0 18px 0;\"\u003e\n\u003cdiv style=\"display:flex;flex-wrap:wrap;align-items:center;justify-content:flex-start;gap:2px;\"\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"230px\" height=\"110px\" viewbox=\"0 0 230 110\"\u003e\u003cpath d=\"M 162.5,28.4 L 168.1,48.4\"\u003e\u003c\/path\u003e\u003cpath d=\"M 168.1,48.4 L 154.8,57.3\"\u003e\u003c\/path\u003e\u003cpath d=\"M 146.9,56.7 L 134.6,47.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 148.9,54.3 L 138.3,45.9\"\u003e\u003c\/path\u003e\u003cpath d=\"M 134.6,47.0 L 139.9,32.7\"\u003e\u003c\/path\u003e\u003cpath d=\"M 134.6,47.0 L 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4px;text-align:center;font-size:12px;line-height:1.3;\"\u003e\n\u003cdiv\u003eluciferase\u003c\/div\u003e\n\u003cdiv style=\"font-size:30px;line-height:1;\"\u003e⟶\u003c\/div\u003e\n\u003cdiv\u003eATP, O₂, Mg²⁺\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;\"\u003e\u003csvg role=\"img\" style=\"max-width:100%;height:auto;\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" stroke=\"#000\" stroke-width=\"1.6\" width=\"230px\" height=\"110px\" viewbox=\"0 0 230 110\"\u003e\u003cpath d=\"M 182.1,24.6 L 188.4,47.2\"\u003e\u003c\/path\u003e\u003cpath d=\"M 188.4,47.2 L 172.8,57.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 164.8,57.1 L 150.3,45.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 167.0,54.3 L 154.5,44.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 150.3,45.6 L 156.6,28.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 150.3,45.6 L 127.7,52.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 127.7,52.0 L 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182.1,24.6\"\u003e\u003c\/path\u003e\u003cpath d=\"M 112.7,40.1 L 127.7,52.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 79.5,89.9 L 95.9,73.0\"\u003e\u003c\/path\u003e\u003cpath d=\"M 182.4,25.7 L 182.1,24.6 L 181.1,24.5\"\u003e\u003c\/path\u003e\u003cpath d=\"M 188.1,46.1 L 188.4,47.2 L 187.6,47.8\"\u003e\u003c\/path\u003e\u003cpath d=\"M 67.9,44.8 L 66.8,44.5 L 66.0,45.3\"\u003e\u003c\/path\u003e\u003cpath d=\"M 56.3,82.9 L 56.7,84.0 L 57.8,84.3\"\u003e\u003c\/path\u003e\u003cpath d=\"M 78.3,89.6 L 79.5,89.9 L 80.3,89.0\"\u003e\u003c\/path\u003e\u003cg style=\"font:12px sans-serif;fill:#000;stroke:none\"\u003e\u003ctext x=\"168.8\" y=\"64.5\" text-anchor=\"middle\"\u003eN\u003c\/text\u003e\u003ctext x=\"158.6\" y=\"27.8\" text-anchor=\"middle\"\u003eS\u003c\/text\u003e\u003ctext x=\"119.5\" y=\"78.2\" text-anchor=\"middle\"\u003eN\u003c\/text\u003e\u003ctext x=\"109.2\" y=\"41.5\" text-anchor=\"middle\"\u003eS\u003c\/text\u003e\u003ctext x=\"31.1\" y=\"59.7\" text-anchor=\"end\"\u003eHO\u003c\/text\u003e\u003ctext x=\"210.5\" y=\"59.7\" text-anchor=\"middle\"\u003eO\u003c\/text\u003e\u003c\/g\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;font-size:20px;padding:0 4px;\"\u003e+\u003c\/div\u003e\n\u003cdiv style=\"display:flex;align-items:center;font-size:14px;padding:0 4px;\"\u003eCO₂ + light\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp style=\"font-size:12px;margin:4px 0 0 0;\"\u003e\u003cem\u003eFirefly luciferase oxidises D-luciferin (left) to oxyluciferin (right). AMP and pyrophosphate are also formed.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eReporter gene assays.\u003c\/strong\u003e Mammalian cells have no luciferase of their own, so the firefly luciferase gene is used as a reporter of gene regulation. After D-luciferin is added, the light produced is proportional to the amount of enzyme. Luciferase reporters are widely used in cell-based assays and in high-throughput screening.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBioluminescence imaging.\u003c\/strong\u003e D-Luciferin is given to mice that carry luciferase-expressing cells, to measure luciferase activity in the living animal.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"margin-bottom: 28px;\"\u003e\n\u003cdiv style=\"background: #002147; padding: 10px 20px; margin-bottom: 0;\"\u003e\u003ch3 style=\"margin: 0; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.70em; font-weight: bold; letter-spacing: 0.12em; text-transform: uppercase; color: #fff;\"\u003eShipping Destinations\u003c\/h3\u003e\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e4e8f0; border-top: none; padding: 12px 16px; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; font-size: 0.95em;\"\u003e\u003cul style=\"margin: 0; padding: 0; list-style: none;\"\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEU \u0026amp; UK: Priority delivery, 2–5 business days.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eUnited States (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eEFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.\u003c\/li\u003e\n\u003cli style=\"padding: 5px 0; border-bottom: 1px solid #f0f0f0;\"\u003e\n\u003cspan style=\"display: inline-block; width: 7px; height: 7px; background: #002147; border-radius: 50%; margin-right: 10px; vertical-align: middle;\"\u003e\u003c\/span\u003eWorldwide: 7–14 business days, selected locations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"NorrChemica™","offers":[{"title":"50 mg","offer_id":55166390894929,"sku":"NOR-2591175-50mg","price":89.2,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":55166390927697,"sku":"NOR-2591175-100mg","price":149.2,"currency_code":"EUR","in_stock":true},{"title":"250 mg","offer_id":55166390960465,"sku":"NOR-2591175-250mg","price":269.2,"currency_code":"EUR","in_stock":true},{"title":"1.0 g","offer_id":55166390993233,"sku":"NOR-2591175-1g","price":598.2,"currency_code":"EUR","in_stock":true},{"title":"5.0 g","offer_id":55387456700753,"sku":"NOR-2591175-5g","price":1895.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0954\/6357\/1793\/files\/NorrChemica_D-Luciferin.png?v=1791059178","url":"https:\/\/www.norrchemica.com\/products\/d-luciferin-cas-2591-17-5","provider":"NorrChemica","version":"1.0","type":"link"}