NorrChemica
Thymidine | CAS 50-89-5 | Powder Ultra-high Purity ≥99.0% | 3rd-Party Tested | DNA Nucleoside | EU Seller
Thymidine | CAS 50-89-5 | Powder Ultra-high Purity ≥99.0% | 3rd-Party Tested | DNA Nucleoside | EU Seller
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🧪 Technical Specifications
- CAS Number: 50-89-5
- SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O
- InChI: InChI=1S/C10H14N2O5/c1-5-2-12(10(16)11-9(5)15)8-3-6(14)7(4-13)17-8/h2,6-8,13-14H,3-4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
- InChIKey: GDSRMUBVXPBCBR-SSEXSRESSA-N
- Molecular Formula: C₁₀H₁₄N₂O₅
- Molecular Weight: 242.23 g/mol
- Purity: ≥99.0% (HPLC)
- Physical Form: White to off-white crystalline powder
- HS Code: 2934.99
- Country of Origin: Finland
- Shelf Life: 36 months unopened (room-temperature dry storage)
- Storage Conditions: Store dry, tightly closed, 2–8 °C; protect from moisture & light. Desiccator recommended after opening.
🔬 Common Scientific Applications
🧬 DNA biosynthesis & salvage — Pulse/chase labeling to track nascent DNA; probe thymidine salvage and thymidylate synthase pathways.
📈 S-phase proliferation assays — Gold-standard substrate for [³H]-thymidine incorporation; non-radioactive alternatives (BrdU/EdU) for imaging & flow cytometry.
🧫 Auxotrophy & metabolic rescue — Complements thyA/tdk mutants (bacteria/yeast) and supports studies with TS/DPD inhibitors (e.g., 5-FU, MTX) impacting dTTP pools.
⚖️ dNTP pool modulation — Controlled supplementation to adjust dTTP and study effects on replication fidelity, fork progression, and genome stability.
🧲 Enzyme assays & standards — Substrate/ligand for thymidine kinase (TK1/TK2), thymidine phosphorylase, and deoxyribonucleoside transporters; ITC/SPR screening.
🧪 Antiviral research — Reference nucleoside in HSV/VZV TK pathways; comparator for thymidine analog prodrugs (AZT, ganciclovir, trifluridine).
🧬 Replication fork mapping — Paired with analogs (IdU/CldU) for DNA fiber assays to quantify fork speed, origin firing, and restart.
🧫 Mitochondrial DNA studies — Tool to probe mtDNA replication and TK2-linked salvage in mitochondrial disease models.
📊 Analytical QC — HPLC/LC-MS retention-time locking, linearity, and response-factor checks in deoxynucleoside panels.
🎓 Teaching & demos — Safe nucleoside for labs on enzyme kinetics, DNA replication, chromatography, and cell-cycle analysis.
For laboratory research and technical use only. Not for human or veterinary use.
⚠️ Safety & Transport
- Hazard Class (UN/DG): Not regulated as dangerous goods
- GHS Signal Word: None needed
- GHS Hazard Statements: Not classified as a hazardous substance under CLP (EC) No 1272/2008
- GHS Precautionary Statements: P280 Wear protective gloves/eye protection. P264 Wash hands thoroughly after handling.
- Dangerous Goods Notes: Ships as non-hazardous chemical unrestricted worldwide
🔎 Advanced Identifiers
- PubChem CID: 5788
Thymidine | CAS 50-89-5 | Powder Ultra-high Purity ≥99.0% | 3rd-Party Tested | DNA Nucleoside | EU Seller
🧪 The NorrChemica™ Standard
- European Certified Origin: Sourced exclusively from accredited EU manufacturers. Full supply chain traceability.
- Analytical Purity: Identity-verified material. Strictly meets or exceeds defined grade specifications.
- 🇪🇺 Intra-EU Trade: Frictionless, tariff-free shipping within the European Union (Single Market).
- 🌍 Global Support: Full customs documentation provided for UK, Canada, and EFTA orders.
- Professional Logistics: Shipped from Finland via premium tracked couriers (UPS/Posti).
🧰 Packaging & Storage
- Supplied in sealed HDPE or amber glass containers
- Store tightly closed in a cool, dry place
- Shelf life: ≥ 36 months under recommended conditions
- Batch-specific CoA and SDS provided
⚠️ Compliance & Safety
- Not for human or veterinary use.
- Mandatory Safety: Always follow the safety instructions and required Personal Protective Equipment (PPE) as detailed in the Safety Data Sheet (SDS).
- Regulatory Status: The specific classification is product-dependent; see the SDS supplied with your order.
- Documentation: A Certificate of Analysis (CoA) and GHS-compliant SDS are available for every order.
- Payment: To ensure regulatory compliance for specialty chemicals, we process orders via Wise (Bank Transfer) or Manual Invoice.
Shipping & Delivery
We ship from our facility in Finland (EU).
- 🇪🇺 EU & UK: typically 2–5 business days.
- 🌍 Selected destinations (e.g., Canada, Japan, Australia, EFTA): typically 4–12 business days.
- ❌ 🇺🇸 United States: shipping unavailable.
- 🧾 Full documentation (CoA + GHS-compliant SDS) included.
🧬 About NorrChemica™
NorrChemica™ is a Finnish supplier of high-purity specialty reagents and niche research materials. We focus on reliable EU shipping, transparent labeling, and accessible pricing for technical users worldwide.
⚖️ Terms of Sale & Disclaimer Sold strictly for laboratory research, analysis, and technical applications. Not for human consumption or food use. By purchasing this item, you confirm professional or educational intent.
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