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NorrChemica™

3,4-Difluorophenylboronic | CAS 168267-41-2 | ≥98%

3,4-Difluorophenylboronic | CAS 168267-41-2 | ≥98%

€22,95 EUR
€22,95 EUR
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Technical Specifications

CAS Number 168267-41-2
SMILES B(C1=CC(=C(C=C1)F)F)(O)O
InChI InChI=1S/C6H5BF2O2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,10-11H
InChIKey RMGYQBHKEWWTOY-UHFFFAOYSA-N
PubChem CID 2734337
Molecular Formula C₆H₅BF₂O₂
Molecular Weight 157.91 g/mol
Purity ≥98.0% (HPLC)
Physical Form White to off-white crystalline powder
HS Code 2931.90.00
Shelf Life 36 months under recommended storage conditions
Storage Conditions Store at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture. May contain small variable amounts of boron anhydrides.
SDS / CoA Download PDF

Common Scientific Applications

Suzuki–Miyaura Cross-Coupling

  • Versatile coupling partner for the synthesis of 3,4-difluorinated biaryl and heteroaryl scaffolds via palladium catalysis
  • The dual 3,4-fluoro substitution creates a strongly electron-withdrawing aromatic system with reactivity distinct from mono-fluorinated isomers
  • Compatible with a broad range of Suzuki conditions including microwave-assisted and aqueous protocols

Organic Synthesis & Building Block Chemistry

  • Key building block for the synthesis of difluorinated aromatic frameworks used across synthetic and biological research
  • Applied in structure-activity relationship studies where dual fluorine substitution modulates physicochemical properties of target molecules
  • Used in the synthesis of fluorodiarylmethanols via reaction with aryl aldehydes under nickel catalysis

Materials Science & Sensor Development

  • Applied in the preparation of conjugated fluorodiazaborinines for chemical sensing applications
  • Used in the synthesis of fluorinated functional organic materials where the 3,4-difluoro pattern provides distinct electronic properties

Boronate Esters & Iterative Synthesis

  • Precursor for 3,4-difluorophenyl boronate esters (pinacol, MIDA, neopentyl glycol) used in iterative cross-coupling strategies
  • Applied in complex molecule assembly where the dual fluorine substitution pattern provides unique electronic and steric properties

The NorrChemica™ Standard

Identity Verified — Batch-verified via analytical QC; documentation available on request.

Direct EU Distribution — Dispatched from Finland for fast delivery to EU-based laboratories.

Professional Logistics — Tracked courier shipping via UPS / Matkahuolto / Posti.

Packaging & Storage

  • Supplied in tightly sealed containers suitable for laboratory handling.
  • Store under recommended conditions as specified on the product label and SDS.
  • Retest period per lot-specific CoA / label under recommended conditions.

Technical Documentation

  • Batch-specific Certificate of Analysis (CoA) included with every order.
  • GHS-compliant Safety Data Sheet (SDS) provided with every shipment.
  • Batch documentation available for institutional procurement.
Payment: Wise (Bank Transfer) or Manual Invoice.
Disclaimer: Research Use Only (RUO) — not for human or veterinary use. Sold strictly for laboratory research and technical applications. By purchasing this item, the buyer confirms professional intent and compliance with applicable regulations.

Safety Information

GHS Pictograms
GHS07 Harmful/Irritant
Signal Word Warning
Hazard Class Not classified as dangerous for transport (ADR/IATA)
Transport Category Not regulated
H-Statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
P-Statements P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

NorrChemica™ is a Finnish supplier of niche research reagents — focused on reliable EU distribution, transparent analytical documentation, and specialist technical support.

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