Lab Journal
Choosing a Coupling Reagent for Amide and Pepti...
Two amide couplings that look identical on paper can give a clean product or a racemised mess, depending only on the reagent and additive. A practical guide to reading the...
Choosing a Coupling Reagent for Amide and Pepti...
Two amide couplings that look identical on paper can give a clean product or a racemised mess, depending only on the reagent and additive. A practical guide to reading the...
Searching a Catalogue by Structure: A Working C...
Most suppliers let you search by name or CAS — which only helps if you already know what you want. NorrChemica's structure search lets you query the catalogue by drawn...
Searching a Catalogue by Structure: A Working C...
Most suppliers let you search by name or CAS — which only helps if you already know what you want. NorrChemica's structure search lets you query the catalogue by drawn...
Phosphine Ligands for Cross-Coupling
A practical guide to choosing phosphine ligands for palladium cross-coupling — how to reason about electronics, sterics, and bite angle, and which ligand to actually reach for in Suzuki–Miyaura and...
Phosphine Ligands for Cross-Coupling
A practical guide to choosing phosphine ligands for palladium cross-coupling — how to reason about electronics, sterics, and bite angle, and which ligand to actually reach for in Suzuki–Miyaura and...
Water-Soluble Diazaborines: Selective Gram-Nega...
Three diazaborines from the recently published J. Med. Chem. 2026 study by Ilina et al. — including the water-soluble sodium salt of the lead FabI inhibitor against E. coli, A....
Water-Soluble Diazaborines: Selective Gram-Nega...
Three diazaborines from the recently published J. Med. Chem. 2026 study by Ilina et al. — including the water-soluble sodium salt of the lead FabI inhibitor against E. coli, A....
Choosing Your Boron Source for Suzuki–Miyaura C...
Protodeboronation rates across heteroarylboronic acids span six orders of magnitude — and esterification does not automatically fix the problem. A mechanistic guide to Suzuki–Miyaura boron reagent selection, grounded in the...
Choosing Your Boron Source for Suzuki–Miyaura C...
Protodeboronation rates across heteroarylboronic acids span six orders of magnitude — and esterification does not automatically fix the problem. A mechanistic guide to Suzuki–Miyaura boron reagent selection, grounded in the...
Naked Fluoride for the Real World — NorrChemica...
We applied quantitative ¹H/¹⁹F NMR to directly measure the active fluoride content of our TMAF–methanol adduct and benchmarked it against two commercial anhydrous sources. The result: 91 mol% F/Me₄N⁺ —...
Naked Fluoride for the Real World — NorrChemica...
We applied quantitative ¹H/¹⁹F NMR to directly measure the active fluoride content of our TMAF–methanol adduct and benchmarked it against two commercial anhydrous sources. The result: 91 mol% F/Me₄N⁺ —...