Lab Journal

Water-Soluble Diazaborines: Selective Gram-Negative Antibiotic Candidates for Synergy Studies and R&D

Water-Soluble Diazaborines: Selective Gram-Nega...

Three diazaborines from the recently published J. Med. Chem. 2026 study by Ilina et al. — including the water-soluble sodium salt of the lead FabI inhibitor against E. coli, A....

Water-Soluble Diazaborines: Selective Gram-Nega...

Three diazaborines from the recently published J. Med. Chem. 2026 study by Ilina et al. — including the water-soluble sodium salt of the lead FabI inhibitor against E. coli, A....

Choosing Your Boron Source for Suzuki–Miyaura Coupling

Choosing Your Boron Source for Suzuki–Miyaura C...

Protodeboronation rates across heteroarylboronic acids span six orders of magnitude — and esterification does not automatically fix the problem. A mechanistic guide to Suzuki–Miyaura boron reagent selection, grounded in the...

Choosing Your Boron Source for Suzuki–Miyaura C...

Protodeboronation rates across heteroarylboronic acids span six orders of magnitude — and esterification does not automatically fix the problem. A mechanistic guide to Suzuki–Miyaura boron reagent selection, grounded in the...

Quantitative ¹H and ¹⁹F NMR spectra of NorrChemica TMAF–MeOH adduct and commercial anhydrous TMAF (Vendor A), with TFB as internal standard. F/Me₄N⁺ = 0.91 (NorrChemica) vs 0.92 (Vendor A).

Naked Fluoride for the Real World — NorrChemica...

We applied quantitative ¹H/¹⁹F NMR to directly measure the active fluoride content of our TMAF–methanol adduct and benchmarked it against two commercial anhydrous sources. The result: 91 mol% F/Me₄N⁺ —...

Naked Fluoride for the Real World — NorrChemica...

We applied quantitative ¹H/¹⁹F NMR to directly measure the active fluoride content of our TMAF–methanol adduct and benchmarked it against two commercial anhydrous sources. The result: 91 mol% F/Me₄N⁺ —...