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NorrChemica™

3-Methoxyphenylboronic Acid | CAS 10365-98-7 | ≥97%

3-Methoxyphenylboronic Acid | CAS 10365-98-7 | ≥97%

€21,95 EUR
€21,95 EUR
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Technical Specifications

CAS Number 10365-98-7
MDL Number MFCD00039111
SMILES COC1=CC=CC(=C1)B(O)O
InChI InChI=1S/C7H9BO3/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5,9-10H,1H3
InChIKey NLLGFYPSWCMUIV-UHFFFAOYSA-N
PubChem CID 2734370
Molecular Formula C₇H₉BO₃
Molecular Weight 151.96 g/mol
Melting Point 160–163 °C
Solubility Soluble in alcoholic solvents, acetonitrile, DMF, DMSO
Purity ≥97%
Physical Form White to light beige crystalline powder
HS Code 2931.90.00
Shelf Life Retest period: 36 months from date of manufacture.
Storage Conditions Store at room temperature. Protect from moisture. May contain varying amounts of boroxine anhydride.
SDS / CoA Download PDF

3-Methoxyphenylboronic acid (3-methoxybenzeneboronic acid; m-anisylboronic acid) is a useful arylboronic acid coupling partner widely employed in Suzuki–Miyaura cross-coupling and related palladium-catalysed transformations for the preparation of methoxy-substituted biaryls, heterobiaryls, and other anisole-derived intermediates. Its meta-methoxy substitution makes it a practical reagent for introducing an electron-rich aryl fragment into synthetic sequences in medicinal chemistry, ligand synthesis, and functional materials research, while retaining the broad utility expected from a standard boronic acid building block. This follows your locked product-description rule: one paragraph only, bold compound name at the start, include a key synonym, and state primary applications without repeating formula, MW, purity, or physical form

Common Scientific Applications

Suzuki–Miyaura Cross-Coupling

  • Widely used arylboronic acid for the construction of meta-methoxy-substituted biaryl and heteroaryl frameworks via palladium-catalysed Suzuki–Miyaura cross-coupling — the electron-donating methoxy group at the 3-position modulates the electronic density of the aryl ring and influences coupling reactivity and regioselectivity
  • Compatible with a broad range of Suzuki protocols including aqueous, microwave-assisted, ligand-free, and base-free conditions, as well as with diverse electrophilic coupling partners including aryl chlorides, bromides, iodides, and triflates
  • Applied in the synthesis of meta-anisyl biaryl scaffolds encountered frequently in pharmaceutical and agrochemical compound libraries

Medicinal Chemistry & Drug Discovery

  • Key building block for the introduction of meta-methoxyphenyl motifs into drug candidates and lead compounds — the methoxy group at the meta position contributes to lipophilicity modulation, metabolic stability profiling, and binding pocket complementarity in structure-activity relationship studies
  • Applied in the synthesis of intermediates for compound libraries targeting diverse protein classes, where the meta-substituted aryl group provides a distinct spatial and electronic profile relative to ortho and para isomers
  • Used in fragment-based drug discovery as a versatile aryl building block amenable to further functionalisation via boronate ester formation, Chan–Lam coupling, and oxidative cross-coupling strategies

Agrochemical & Materials Applications

  • Applied in the synthesis of meta-methoxyphenyl-containing agrochemical intermediates where the methoxy substituent influences bioactivity, environmental persistence, and physicochemical properties of the final active substance
  • Used in the development of functional organic materials, conjugated polymers, and sensors where the boronic acid group enables reversible diol binding and dynamic boronate ester formation for stimuli-responsive material design

Boronate Esters & Iterative Synthesis

  • Precursor for meta-methoxyphenyl boronate esters (pinacol, MIDA, neopentyl glycol esters) applied in iterative cross-coupling strategies and complex molecule assembly workflows
  • Applied in diol-sensing and saccharide recognition systems where the boronic acid group forms reversible covalent bonds with 1,2- and 1,3-diols — a well-established motif in supramolecular chemistry and chemosensor design

Shipping Destinations

  • EU & UK: Priority delivery, 2–5 business days.
  • United States (DDP): 3–7 business days, duties and taxes prepaid.
  • EFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.
  • Worldwide: 7–14 business days, selected locations.

The NorrChemica™ Standard

Identity Verified — Batch-verified via analytical QC; documentation available on request.

Direct EU Distribution — Dispatched from Finland for fast delivery to EU-based laboratories.

Professional Logistics — Tracked courier shipping via UPS / Matkahuolto / Posti.

Packaging & Storage

  • Supplied in tightly sealed containers suitable for laboratory handling.
  • Store under recommended conditions as specified on the product label and SDS.
  • Retest period per lot-specific CoA / label under recommended conditions.

Technical Documentation

  • Batch-specific Certificate of Analysis (CoA) included with every order.
  • GHS-compliant Safety Data Sheet (SDS) provided with every shipment.
  • Batch documentation available for institutional procurement.
Payment: Wise (Bank Transfer) or Manual Invoice.
Disclaimer: Research Use Only (RUO) — not for human or veterinary use. Sold strictly for laboratory research and technical applications. By purchasing this item, the buyer confirms professional intent and compliance with applicable regulations.

Safety Information

GHS Pictograms
GHS07 Harmful/Irritant
Signal Word Warning
Hazard Class None — not subject to transport regulations
Transport Category Not classified as dangerous goods for transport (ADR/IATA/IMDG)
H-Statements H302 — Harmful if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation
P-Statements P261 — Avoid breathing dust/fume/gas/mist/vapours/spray
P264 — Wash thoroughly after handling
P271 — Use only outdoors or in a well-ventilated area
P301 + P312 — IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell
P302 + P352 — IF ON SKIN: Wash with plenty of water
P305 + P351 + P338 — IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

NorrChemica™ is a Finnish supplier of niche research reagents — focused on reliable EU distribution, transparent analytical documentation, and specialist technical support.

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