NorrChemica™
Potassium Cyclopropyltrifluoroborate
Potassium Cyclopropyltrifluoroborate | CAS 1065010-87-8 | ≥98%
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Technical Specifications
| CAS Number | 1065010-87-8 |
| EC / EINECS Number | 678-462-3 |
| MDL Number | MFCD09265031 |
| SMILES | [B-](C1CC1)(F)(F)F.[K+] |
| InChI | InChI=1S/C3H5BF3.K/c5-4(6,7)3-1-2-3;/h3H,1-2H2;/q-1;+1 |
| InChIKey | CFMLURFHOSOXRC-UHFFFAOYSA-N |
| PubChem CID | 23697338 |
| Molecular Formula | C₃H₅BF₃K |
| Molecular Weight | 147.98 g/mol |
| Melting Point | 348–350 °C |
| Solubility | Soluble in water, methanol, acetone, acetonitrile, DMSO and DMF; poorly soluble in diethyl ether, hexane, toluene and dichloromethane. |
| Purity | ≥98% |
| Physical Form | White crystalline powder |
| HS Code | 2931.90 |
| Shelf Life | Retest period: 36 months from date of manufacture |
| Storage Conditions | Store in a cool, dry place in a tightly sealed container |
Product Description & Scientific Applications
Potassium Cyclopropyltrifluoroborate is a bench-stable salt that transfers a cyclopropyl group in cross-coupling and radical C–C bond-forming reactions. As a masked boronic acid, it hydrolyses slowly in protic media to release the active nucleophile in situ.
Applications and Reactions
Suzuki–Miyaura coupling: couples with aryl and heteroaryl chlorides, bromides, and mesylated phenols to give arylcyclopropanes, a useful motif in medicinal-chemistry, agrochemical, and fragment-library synthesis.
Csp³–Csp³ alkyl–alkyl coupling: couples with benzyl chlorides to give benzylcyclopropanes, a harder transformation than coupling with aryl electrophiles.
Minisci-type C–H alkylation: under photoredox conditions the cyclopropyl radical adds to electron-deficient N-heteroarenes, installing the group by direct C–H functionalisation without prior halogenation.
Chan–Lam cyclopropylation: transfers the cyclopropyl group to phenols and selected azaheterocycles under Cu-mediated oxidative coupling to access cyclopropyl ethers and N-cyclopropyl heterocycles.
Further Reading
For boronic acids, boronic esters, organotrifluoroborates, protodeboronation, and Suzuki–Miyaura reagent selection, see NorrChemica's Lab Journal guide: Choosing Your Boron Source for Suzuki–Miyaura Coupling.
Shipping Destinations
- EU & UK: Priority delivery, 2–5 business days.
- United States (DDP): 3–7 business days, duties and taxes prepaid.
- EFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.
- Worldwide: 7–14 business days, selected locations.
Safety Information
| GHS Pictograms |
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| Signal Word | Warning |
| Hazard Class | None — not subject to transport regulations |
| Transport Category | Not classified as dangerous goods for transport (ADR/IATA/IMDG) |
| H-Statements | H315 - H319 - H335 |
| P-Statements | P261 - P264 - P271 - P280 - P302+P352 - P304+P340 - P305+P351+P338 - P332+P313 - P337+P313 - P362+P364 - P501 |
Documentation
| Safety Data Sheet | Download PDF |
