4-Bromophenylboronic Acid | CAS 5467-74-3 | ≥98%

Suzuki–Miyaura Cross-Coupling

• One of the most widely used arylboronic acid coupling partners for the synthesis of 4-bromobiaryl scaffolds via palladium catalysis
• The para-bromo substituent provides moderate electron-withdrawal combined with a uniquely versatile C–Br bond available for further synthetic elaboration
• Compatible with a broad range of Suzuki conditions including aqueous, microwave-assisted, and ligand-free protocols

Dual-Reactivity Building Block

• Unique dual reactivity — the boronic acid participates in Suzuki coupling while the retained C–Br bond enables subsequent oxidative addition, halogen-metal exchange, or further cross-coupling
• Widely used in iterative synthesis strategies where sequential functionalisation of both the boron and bromine handles is required
• Applied in agrochemistry for the synthesis of brominated aromatic intermediates used in crop protection compounds

Materials Science & Functional Organic Chemistry

• Applied in the synthesis of brominated conjugated materials, organic semiconductors, and functional aromatic polymers
• Used in the development of sensors where the boron functionality enables reversible diol binding and the bromine provides an additional synthetic handle

Boronate Esters & Iterative Synthesis

• Precursor for 4-bromophenyl boronate esters (pinacol, MIDA, neopentyl glycol) used in iterative cross-coupling strategies
• Applied in complex molecule assembly where both the boron and bromo groups are exploited sequentially in multi-step synthesis