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4-Chlorophenylboronic Acid | CAS 1679-18-1 | ≥98%

4-Chlorophenylboronic Acid | CAS 1679-18-1 | ≥98%

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Technical Specifications

CAS Number 1679-18-1
SMILES B(C1=CC=C(C=C1)Cl)(O)O
InChI InChI=1S/C6H6BClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
InChIKey CAYQIZIAYYNFCS-UHFFFAOYSA-N
PubChem CID 74299
Molecular Formula C₆H₆BClO₂
Molecular Weight 156.38 g/mol
Purity ≥98.0% (HPLC)
Physical Form White to off-white crystalline powder
HS Code 2931.90.00
Shelf Life 36 months under recommended storage conditions
Storage Conditions Store at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture. May contain small variable amounts of boron anhydrides.
SDS / CoA Download PDF

Common Scientific Applications

Suzuki–Miyaura Cross-Coupling

  • One of the most widely used arylboronic acid coupling partners for the synthesis of 4-chlorobiaryl scaffolds via palladium catalysis
  • The para-chloro substituent provides moderate electron-withdrawal and a versatile handle for further synthetic elaboration
  • Compatible with a broad range of coupling protocols including microwave-assisted, aqueous, and ligand-free conditions

Organic Synthesis & Building Block Chemistry

  • Widely used building block for the synthesis of chlorinated aromatic frameworks across synthetic chemistry research
  • Applied in agrochemistry for the preparation of chlorinated aromatic intermediates used in crop protection compounds
  • The para-chloro group can be further functionalised — enabling substitution, metal insertion, and cross-coupling reactions on the product

Materials Science & Functional Organic Chemistry

  • Applied in the synthesis of chlorinated conjugated materials and organic semiconductors
  • Used in the preparation of functional aromatic polymers where the chloro substituent modulates electronic and physical properties

Boronate Esters & Iterative Synthesis

  • Precursor for 4-chlorophenyl boronate esters (pinacol, MIDA, neopentyl glycol) used in iterative cross-coupling strategies
  • Applied in complex molecule assembly where the retained chloro group provides a handle for subsequent functionalisation steps

The NorrChemica™ Standard

Identity Verified — Batch-verified via analytical QC; documentation available on request.

Direct EU Distribution — Dispatched from Finland for fast delivery to EU-based laboratories.

Professional Logistics — Tracked courier shipping via UPS / Matkahuolto / Posti.

Packaging & Storage

  • Supplied in tightly sealed containers suitable for laboratory handling.
  • Store under recommended conditions as specified on the product label and SDS.
  • Retest period per lot-specific CoA / label under recommended conditions.

Technical Documentation

  • Batch-specific Certificate of Analysis (CoA) included with every order.
  • GHS-compliant Safety Data Sheet (SDS) provided with every shipment.
  • Batch documentation available for institutional procurement.
Payment: Wise (Bank Transfer) or Manual Invoice.
Disclaimer: Research Use Only (RUO) — not for human or veterinary use. Sold strictly for laboratory research and technical applications. By purchasing this item, the buyer confirms professional intent and compliance with applicable regulations.

Safety Information

GHS Pictograms
GHS07 Harmful/Irritant
Signal Word Warning
Hazard Class Not classified as dangerous for transport (ADR/IATA)
Transport Category Not regulated
H-Statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H332 (Harmful if inhaled)
P-Statements P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, P403+P233, P405, P501

NorrChemica™ is a Finnish supplier of niche research reagents — focused on reliable EU distribution, transparent analytical documentation, and specialist technical support.

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