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NorrChemica™

4-Fluorophenylboronic Acid | CAS 1765-93-1 | ≥98%

4-Fluorophenylboronic Acid | CAS 1765-93-1 | ≥98%

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Technical Specifications

CAS Number 1765-93-1
SMILES OB(O)c1ccc(F)cc1
InChI InChI=1S/C6H6BFO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
InChIKey LBUNNMJLXWQQBY-UHFFFAOYSA-N
PubChem CID 285645
Molecular Formula C₆H₆BFO₂
Molecular Weight 139.92 g/mol
Purity ≥98.0% (HPLC)
Physical Form White to off-white crystalline powder
HS Code 2931.90.00
Shelf Life 36 months under recommended storage conditions
Storage Conditions Store at room temperature. Keep container tightly closed in a dry place. Mildly hygroscopic — protect from moisture. May contain small variable amounts of boron anhydrides.
SDS / CoA Download PDF

Common Scientific Applications

Suzuki–Miyaura Cross-Coupling

  • Benchmark coupling partner for the synthesis of 4-fluorobiaryl scaffolds via palladium catalysis
  • The para-fluoro substituent imparts unique electron-withdrawing properties widely exploited in medicinal chemistry
  • Compatible with microwave-assisted Suzuki coupling, Mizoroki–Heck, and Cu-catalysed Petasis reactions

Drug Discovery & Medicinal Chemistry

  • Key building block for fluorinated pharmaceuticals — fluorine acts as a bioisostere improving metabolic stability, membrane permeability, and binding affinity
  • Used in the synthesis of biologically active terphenyls and complex fluorinated aromatic frameworks
  • Applied in the development of anti-cancer agents and other therapeutic drug candidates

Kinase Inhibitor Research

  • Reagent in the synthesis of fluorinated heterocycles used as kinase inhibitors
  • Used to develop analog-sensitive kinase probes for real-time study of cellular kinase function

Boronate Esters & Bioconjugation

  • Precursor for 4-fluorophenyl boronate esters (pinacol, MIDA, neopentyl glycol) used in iterative cross-coupling strategies
  • Applied in bioconjugation and biosensor development for diagnostic and materials science applications

The NorrChemica™ Standard

Identity Verified — Batch-verified via analytical QC; documentation available on request.

Direct EU Distribution — Dispatched from Finland for fast delivery to EU-based laboratories.

Professional Logistics — Tracked courier shipping via UPS / Matkahuolto / Posti.

Packaging & Storage

  • Supplied in tightly sealed containers suitable for laboratory handling.
  • Store under recommended conditions as specified on the product label and SDS.
  • Retest period per lot-specific CoA / label under recommended conditions.

Technical Documentation

  • Batch-specific Certificate of Analysis (CoA) included with every order.
  • GHS-compliant Safety Data Sheet (SDS) provided with every shipment.
  • Batch documentation available for institutional procurement.
Payment: Wise (Bank Transfer) or Manual Invoice.
Disclaimer: Research Use Only (RUO) — not for human or veterinary use. Sold strictly for laboratory research and technical applications. By purchasing this item, the buyer confirms professional intent and compliance with applicable regulations.

Safety Information

GHS Pictograms
GHS07 Harmful/Irritant
Signal Word Warning
Hazard Class Not classified as dangerous for transport (ADR/IATA)
Transport Category Not regulated
H-Statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
P-Statements P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P321, P330, P332+P317, P337+P317, P403+P233, P405, P501

NorrChemica™ is a Finnish supplier of niche research reagents — focused on reliable EU distribution, transparent analytical documentation, and specialist technical support.

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