NorrChemica™
1-Bromo-4-iodobenzene
1-Bromo-4-iodobenzene | CAS 589-87-7 | ≥98%
| Pack size | Excl. VAT | Incl. VAT | Add to cart |
|---|---|---|---|
| 10 g | €39,90 | ||
| 25 g | €54,20 | ||
| 50 g | €89,20 | ||
| 100 g | €129,20 | ||
| 250 g | €189,20 | ||
| 500 g | €239,20 |
Taxes and fees, e.g. VAT, included in the price. Shipping calculated at checkout.Free shipping on EU, UK and EFTA orders above €250, and above €400 to the rest of the world.
Technical Specifications
| CAS Number | 589-87-7 |
| EC / EINECS Number | 209-662-7 |
| MDL Number | MFCD00001051 |
| SMILES | C1=CC(=CC=C1Br)I |
| InChI | InChI=1S/C6H4BrI/c7-5-1-3-6(8)4-2-5/h1-4H |
| InChIKey | UCCUXODGPMAHRL-UHFFFAOYSA-N |
| PubChem CID | 11522 |
| Molecular Formula | C₆H₄BrI |
| Molecular Weight | 282.9 g/mol |
| Melting Point | 89–91 °C |
| Solubility | Insoluble in water. |
| Purity | ≥98% |
| Physical Form | White to Almost white powder to crystal |
| HS Code | 2903.99 |
| Shelf Life | Retest period: 36 months from date of manufacture |
| Storage Conditions | Store at room temperature in a tightly sealed container, protected from light. |
Product Description & Scientific Applications
1-Bromo-4-iodobenzene (C₆H₄BrI) has an iodine atom and a bromine atom at para positions of a benzene ring.
Amination. 1-Bromo-4-iodobenzene is aminated catalytically with high selectivity at the C–I bond. With toluidine, the product is the 4-bromodiarylamine.
Ketone synthesis. Under mechanochemical conditions, calcium inserts into the C–I bond without affecting the C–Br bond, and reaction with a carboxylic acid gives the ketone.
Negishi coupling. 1-Bromo-4-iodobenzene was the substrate used to demonstrate sequential, chemoselective coupling with a CoBr₂/DMAc catalyst system.
Sulfonylation. For 1,4-disulfonylation, 1-bromo-4-iodobenzene is a better substrate for sequential coupling than 1,4-diiodobenzene.
Carbon-11 labelling. Under palladium-mediated conditions optimised for aryl iodides, the aryl bromide does not react. 1-Bromo-4-iodobenzene can therefore be used as a starting material for [carbonyl-¹¹C]acyl amidines.
Polymer-supported phosphine. ROMPgel-supported triphenylphosphine is made in three steps from norbornadiene, 1-bromo-4-iodobenzene and chlorodiphenylphosphine.
Luminescent co-crystals. With pyromellitic diimide, 1-bromo-4-iodobenzene forms a 1:1 co-crystal in which it is the heavy-atom donor. The crystals show intense green emission, while donor and acceptor alone are weakly emissive.
Selectivity limit. In copper-catalysed N-arylation of N-acetylhistidine methyl ester, 1-bromo-4-iodobenzene gives a mixture of bromophenyl and iodophenyl products, so coupling takes place at both halogens.
Shipping Destinations
- EU & UK: Priority delivery, 2–5 business days.
- United States (DDP): 3–7 business days, duties and taxes prepaid.
- EFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.
- Worldwide: 7–14 business days, selected locations.
Safety Information
| GHS Pictograms |
|
| Signal Word | Warning |
| Hazard Class | Not regulated for transport |
| Transport Category | Not classified as dangerous goods for transport (ADR/IATA/IMDG) |
| H-Statements | H315 - H319 - H335 |
| P-Statements | P261 - P264 - P271 - P280 - P302+P352 - P304+P340 - P305+P351+P338 - P332+P313 - P337+P313 - P362+P364 - P501 |
Documentation
| Safety Data Sheet | Download PDF |
