NorrChemica™
L-Cysteine
L-Cysteine | CAS 52-90-4 | ≥97%
Pack sizes & prices
| Pack size | Excl. VAT | Incl. VAT | Add to cart |
|---|---|---|---|
| 5.0 g | €49,20 | ||
| 10 g | €54,20 | ||
| 25 g | €68,20 | ||
| 50 g | €79,20 | ||
| 100 g | €89,20 | ||
| 500 g | €129,20 |
Taxes and fees, e.g. VAT, included in the price. Shipping calculated at checkout.Free shipping on EU, UK and EFTA orders above €250, and above €400 to the rest of the world.
Technical Specifications
| CAS Number | 52-90-4 |
| EC / EINECS Number | 200-158-2 |
| MDL Number | MFCD00064306 |
| RTECS Number | HA1600000 |
| SMILES | C([C@@H](C(=O)O)N)S |
| InChI | InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1 |
| InChIKey | XUJNEKJLAYXESH-REOHCLBHSA-N |
| PubChem CID | 5862 |
| Molecular Formula | C₃H₇NO₂S |
| Molecular Weight | 121.16 g/mol |
| Melting Point | 240 °C (dec.) |
| Solubility | Soluble in water, 1 M hydrochloric acid, ethanol, acetic acid and aqueous ammonia. Insoluble in ether, acetone, ethyl acetate and benzene. |
| Log Pow | -2.49 |
| Purity | ≥97% |
| Physical Form | White crystalline powder |
| HS Code | 2930.90 |
| Shelf Life | Retest period: 36 months from date of manufacture |
| Storage Conditions | Store under inert gas at room temperature in a tightly sealed container, protected from light and moisture. |
Product Description & Scientific Applications
L-Cysteine is a sulfur-containing proteinogenic amino acid that is incorporated into proteins as directed by the genetic code. In proteins, cysteine provides the disulfide linkage.
Its thiol side chain takes part in a variety of oxidation–reduction reactions within the cell. L-Cysteine is an essential precursor of inorganic sulfate and coenzyme A, and it is essential and limiting for the formation of the antioxidant glutathione within the cell. Cysteine is also involved in the formation of hydrogen sulfide, which is used as a signalling molecule.
Thiol–maleimide chemistry. L-Cysteine has been used to quench unreacted maleimide during antibody grafting. Its reaction with 6-maleimidohexanoic acid is a Michael-type thiol–maleimide addition.
General reaction: L-cysteine + N-substituted maleimide → thioether adduct (Michael-type thiol–maleimide addition).
S-Nitrosylation. L-Cysteine has been used to prepare S-nitrosocysteine stock solutions, which induce S-nitrosylation as a reversible cysteine modification.
General reaction: L-cysteine → S-nitrosocysteine.
Thiazolidine synthesis. L-Cysteine, aldehydes and 3-(acetylsulfanyl)propionyl chloride have been used to prepare 2-substituted (2R,4R)-3-(3-mercaptopropionyl)thiazolidine-4-carboxylic acids.
General reaction: L-cysteine + aldehyde + 3-(acetylsulfanyl)propionyl chloride → 2-substituted (2R,4R)-3-(3-mercaptopropionyl)thiazolidine-4-carboxylic acid.
Raw material for cysteine derivatives. L-Cysteine is a key raw material for the manufacture of N-acetyl-L-cysteine and S-carboxymethyl-L-cysteine.
General reaction: L-cysteine → N-acetyl-L-cysteine.
General reaction: L-cysteine → S-carboxymethyl-L-cysteine.
Shipping Destinations
- EU & UK: Priority delivery, 2–5 business days.
- United States (DDP): 3–7 business days, duties and taxes prepaid.
- EFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.
- Worldwide: 7–14 business days, selected locations.
Safety Information
| Hazard Class | Not regulated for transport. |
| Transport Category | Not classified as dangerous goods for transport (ADR/IATA/IMDG) |
Documentation
| Safety Data Sheet | Download PDF |
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