NorrChemica™
Coumarin 7
Coumarin 7 | CAS 27425-55-4 | ≥98%
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Technical Specifications
| CAS Number | 27425-55-4 |
| EC / EINECS Number | 248-451-4 |
| MDL Number | MFCD00051348 |
| SMILES | CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C3=NC4=CC=CC=C4N3 |
| InChI | InChI=1S/C20H19N3O2/c1-3-23(4-2)14-10-9-13-11-15(20(24)25-18(13)12-14)19-21-16-7-5-6-8-17(16)22-19/h5-12H,3-4H2,1-2H3,(H,21,22) |
| InChIKey | GOLORTLGFDVFDW-UHFFFAOYSA-N |
| PubChem CID | 94381 |
| Molecular Formula | C₂₀H₁₉N₃O₂ |
| Molecular Weight | 333.38 g/mol |
| Melting Point | 238-243 °C |
| Solubility | Soluble in chloroform, dichloromethane, DMSO, DMF and warm ethanol; sparingly soluble in water. |
| Purity | ≥98% |
| Physical Form | White to Light yellow powder to crystal |
| HS Code | 2933.99 |
| Country of Origin | Finland |
| Shelf Life | Retest period: 36 months from date of manufacture |
| Storage Conditions | Store in a cool, dry place in a tightly sealed container, protected from light |
Product Description & Scientific Applications
Coumarin 7 fluoresces from an intramolecular charge-transfer (ICT) excited state, with the 7-diethylamino group as donor and the 3-(2-benzimidazolyl) substituent as acceptor. It emits from a planar ICT state across the solvent range, stabilised by an intramolecular hydrogen bond between the benzimidazole N–H and the lactone carbonyl. Emission is solvatochromic: in water the neutral dye absorbs at 462 nm and emits near 500 nm with a fluorescence quantum yield of 0.15, while protonation moves absorption to 475 nm and emission to 512 nm and lowers the quantum yield to 0.05. In high-polarity protic solvents, beyond a Lippert–Mataga Δf of about 0.31, a nonfluorescent twisted ICT (TICT) state opens a nonradiative channel, so quantum yield and fluorescence lifetime fall below their linear solvent-polarity correlation.
Common Scientific Applications
- Laser dye. Used in ethanolic solution as a gain medium, and as a laser-induced-fluorescence staining fluorophore.
- Environment-reporting fluorophore. The large solvatochromic and host-induced spectral shifts make Coumarin 7 a reporter of local polarity and confinement.
- Host–guest photophysics. Encapsulation in sulfobutylether-β-cyclodextrin suppresses the TICT channel, doubling the aqueous quantum yield from 0.15 to 0.30 and raising photostability.
- Ratiometric sensing. Driving the monomer–aggregate equilibrium with poly(styrene sulfonate) at pH about 3 gives a readout at 650 nm against the 513 nm monomer band.
Shipping Destinations
- EU & UK: Priority delivery, 2–5 business days.
- United States (DDP): 3–7 business days, duties and taxes prepaid.
- EFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.
- Worldwide: 7–14 business days, selected locations.
Safety Information
| GHS Pictograms |
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| Signal Word | Warning |
| Hazard Class | Not regulated for transport |
| Transport Category | Not classified as dangerous goods for transport (ADR/IATA/IMDG) |
| H-Statements | H315 - H319 - H335 |
| P-Statements | P261 - P264 - P271 - P280 - P302+P352 - P304+P340 - P305+P351+P338 - P332+P313 - P337+P313 - P362+P364 - P501 |
