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Riboflavin

CAS 83-88-5 ≥98%

Riboflavin | CAS 83-88-5 | ≥98%

Pack sizes & prices

Pack sizes and prices, excluding and including VAT
Pack size Excl. VAT Incl. VAT Add to cart
5.0 g €39,90
10 g €54,20
25 g €74,20
50 g €98,20
100 g €124,20
250 g €169,20
500 g €249,20

Taxes and fees, e.g. VAT, included in the price. Shipping calculated at checkout.Free shipping on EU, UK and EFTA orders above €250, and above €400 to the rest of the world.

Technical Specifications

CAS Number 83-88-5
EC / EINECS Number 201-507-1
MDL Number MFCD00005022
RTECS Number VJ1400000
SMILES CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO)O)O)O
InChI InChI=1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
InChIKey AUNGANRZJHBGPY-SCRDCRAPSA-N
PubChem CID 493570
Molecular Formula C₁₇H₂₀N₄O₆
Molecular Weight 376.4 g/mol
Melting Point 290 °C (dec.)
Solubility Very slightly soluble in water (0.07–0.1 g/L at 20–25 °C; varies with crystal form). Less soluble in ethanol (0.045 g/L at 27.5 °C). Soluble in dilute alkali hydroxide solutions, with decomposition; such solutions are light-sensitive. Insoluble in diethyl ether, chloroform, acetone and benzene.
Purity ≥98%
Physical Form White to yellow to orange powder crystalline solid
HS Code 2936.23
Shelf Life Retest period: 36 months from date of manufacture
Storage Conditions Keep container tightly closed in a dry and well-ventilated place. Protect from light.

Product Description & Scientific Applications

Riboflavin (vitamin B2) is the precursor of FMN and FAD, the prosthetic groups of the oxidation-reduction enzymes known as flavoproteins. In water, its neutral form fluoresces with a quantum yield of about 0.26 above pH 4, and this fluorescence decreases strongly below pH 4.

Stability. The dry solid is stable to diffuse light, but riboflavin is highly photolabile in solution and unstable in alkaline solution. Neutral and acidic solutions are stable in the dark.

Flavin cofactor synthesis. A bifunctional FAD synthetase converts riboflavin first to FMN and then to FAD. This route gives isotopically labelled FAD, used to study flavin-dependent thymidylate synthase.

Hydrogel crosslinking. With arginine as co-initiator, riboflavin is a natural photoinitiator for gelatin methacryloyl (GelMA) hydrogels crosslinked by visible light.

Photocatalysis. Riboflavin mediates a highly (Z)-selective, catalytic E→Z isomerisation of activated olefins.

Cell culture media. Riboflavin is a supplement in cell and embryo culture media and in bacterial basal media. In light-exposed medium, riboflavin with tryptophan or tyrosine is required to form hydrogen peroxide at levels lethal to human cells.

Shipping Destinations

  • EU & UK: Priority delivery, 2–5 business days.
  • United States (DDP): 3–7 business days, duties and taxes prepaid.
  • EFTA Countries (DDP): 3–7 business days, duties and taxes prepaid.
  • Worldwide: 7–14 business days, selected locations.

Safety Information

Hazard Class Not classified as dangerous goods
Transport Category Not dangerous goods (ADR/IATA/IMDG)

Documentation

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